Journal ArticleDOI
Effects of Intermittent Fasting on Health, Aging, and Disease
Rafael de Cabo,Mark P. Mattson +1 more
TLDR
Effects of Intermittent Fasting on Health and Aging evidence is accumulating that eating in a 6-hour period and fasting for 18 hours can trigger a metabolic switch from glucose-based to ketone-base fasting.Abstract:
Effects of Intermittent Fasting on Health and Aging Evidence is accumulating that eating in a 6-hour period and fasting for 18 hours can trigger a metabolic switch from glucose-based to ketone-base...read more
Citations
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Journal ArticleDOI
Early Recognition of Overweight Hyperglycaemia May Improve Clinical Outcomes in Type 2 Diabetes
TL;DR: In this paper , the authors present the evolution of their understanding and compelling reasons to reframe diabetes in severely obese individuals to what it really is -overweight hyperglycaemia.
Journal ArticleDOI
Examination of sleep in relation to dietary and lifestyle behaviors during Ramadan: A multi-national study using structural equation modeling among 24,500 adults amid COVID-19
Moien Ab Khan,Ahmed S. BaHammam,A. Amanatullah,Khaled Obaideen,Teresa Arora,Habiba I. Ali,Leila Cheikh Ismail,Dana Abdelrahim,Mohammed Al-Houqani,Kholoud K Allaham,Rand Abdalrazeq,Wahid AlOweiwi,Somayea Sultana Mim,Ammar Mektebi,Sohrab Amiri,S. K. Sulaiman,Syed Fahad Javaid,Mohammad Delwer Hossain Hawlader,Fatimah I Tsiga-Ahmed,Iffat Elbarazi,Saskiyanto Manggabarani,Gamechu Atomsa Hunde,Sabrina Chelli,Mitra Sotoudeh,M. Faris +24 more
TL;DR: In this article , structural equation modeling (SEM) was used to examine how dietary and lifestyle factors affected sleep parameters and found that increasing the intake of fruits, vegetables, and plant-based proteins are important factors that could help improve healthy sleep for those observing Ramadan fasting.
Journal ArticleDOI
Does intermittent fasting impact mental disorders? A systematic review with meta-analysis.
Rubén Fernández-Rodríguez,Vicente Martínez-Vizcaíno,Arthur Eumann Mesas,Blanca Notario-Pacheco,María Medrano,Leonie K. Heilbronn +5 more
TL;DR: IF modalities did not negatively impact mental disorders in the general population, and IF showed a positive influence on diminishing depression scores, and did not modify anxiety or mood.
Journal ArticleDOI
Influence of an acute fast on ambulatory blood pressure and autonomic cardiovascular control
TL;DR: The results show that acute fasting is consistent with improved cardiovascular health: such improvements are driven by reduced ambulatory arterial pressure and enhanced vagal-cardiac modulation.
References
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Caloric Restriction Delays Disease Onset and Mortality in Rhesus Monkeys
Ricki J. Colman,Rozalyn M. Anderson,Sterling C. Johnson,Erik K. Kastman,Kristopher J. Kosmatka,T. Mark Beasley,David B. Allison,Christina Cruzen,Heather A. Simmons,Joseph W. Kemnitz,Richard Weindruch +10 more
TL;DR: Findings of a 20-year longitudinal adult-onset CR study in rhesus monkeys aimed at filling this critical gap in aging research demonstrate that CR slows aging in a primate species.
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Risk of dementia in diabetes mellitus: a systematic review
TL;DR: The findings of mechanistic studies suggest that vascular disease and alterations in glucose, insulin, and amyloid metabolism underlie the pathophysiology of dementia, but which of these mechanisms are clinically relevant is unclear.
Journal ArticleDOI
Time-Restricted Feeding without Reducing Caloric Intake Prevents Metabolic Diseases in Mice Fed a High-Fat Diet
Megumi Hatori,Christopher Vollmers,Amir Zarrinpar,Amir Zarrinpar,Luciano DiTacchio,Eric A. Bushong,Shubhroz Gill,Mathias Leblanc,Amandine Chaix,Matthew S. Joens,James A. J. Fitzpatrick,Mark H. Ellisman,Satchidananda Panda +12 more
TL;DR: Mice under tRF consume equivalent calories from HFD as those with ad lib access yet are protected against obesity, hyperinsulinemia, hepatic steatosis, and inflammation and have improved motor coordination.
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Starvation in man.
TL;DR: In this article, it was shown that decreased levels of active T3 may play a role by sparing otherwise obligated calories by decreasing metabolic needs, but this can be nullified by amino acid or protein supplementation.
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Metabolic control of mitochondrial biogenesis through the PGC-1 family regulatory network.
TL;DR: The results point to a central role for the PGC-1 family in integrating mitochondrial biogenesis and energy production with many diverse cellular functions.