Journal ArticleDOI
Effects of Intermittent Fasting on Health, Aging, and Disease
Rafael de Cabo,Mark P. Mattson +1 more
TLDR
Effects of Intermittent Fasting on Health and Aging evidence is accumulating that eating in a 6-hour period and fasting for 18 hours can trigger a metabolic switch from glucose-based to ketone-base fasting.Abstract:
Effects of Intermittent Fasting on Health and Aging Evidence is accumulating that eating in a 6-hour period and fasting for 18 hours can trigger a metabolic switch from glucose-based to ketone-base...read more
Citations
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Journal ArticleDOI
Perspective: Time-Restricted Eating Compared with Caloric Restriction: Potential Facilitators and Barriers of Long-Term Weight Loss Maintenance.
Sydney G O'Connor,Patrick Boyd,Caitlin P. Bailey,Marissa Shams-White,Tanya Agurs-Collins,Kara L. Hall,Jill Reedy,Edward R. Sauter,Susan M. Czajkowski +8 more
TL;DR: The potential multilevel facilitators and barriers of TRE for long-term weight loss maintenance in comparison with the more commonly used diet strategy, caloric restriction (CR) are explored.
Journal ArticleDOI
A Pesco-Mediterranean Diet With Intermittent Fasting: JACC Review Topic of the Week.
James H. O'Keefe,Noel Torres-Acosta,Evan L. O’Keefe,Ibrahim M. Saeed,Carl J. Lavie,Sarah E. Smith,Emilio Ros +6 more
TL;DR: C cumulative evidence regarding diet and health is reviewed, incorporating data from landmark clinical trials of the Mediterranean diet and recommendations from recent authoritative guidelines, to support the hypothesis that a Pesco-Mediterranean diet is ideal for optimizing cardiovascular health.
Journal ArticleDOI
Alzheimer's Disease and Diabetes: Role of Diet, Microbiota and Inflammation in Preclinical Models.
Maria Jose Carranza-Naval,Maria Vargas-Soria,Carmen Hierro-Bujalance,Gloria Baena-Nieto,Monica Garcia-Alloza,Carmen Infante-Garcia,Angel del Marco +6 more
TL;DR: A comprehensive review of current literature on the relation between dysbiosis, altered inflammatory cytokines profile and microglia in preclinical models of AD, T2DM and models that reproduce both diseases as commonly observed in the clinic is provided in this article.
Journal ArticleDOI
Time-restricted eating and circadian rhythms: the biological clock is ticking.
Jéssica do Nascimento Queiroz,Rodrigo Cauduro Oliveira Macedo,Rodrigo Cauduro Oliveira Macedo,Grant M. Tinsley,Alvaro Reischak-Oliveira +4 more
TL;DR: Time-restricted eating (TRE) consists of limiting daily nutrient consumption to a period of 4 to 12 hours in order to extend the time spent in the fasted state, and some evidence indicates that greater promotion of health via TRE may be achieved if the nutrient intake period occurs earlier in the day.
Journal ArticleDOI
Effects of Ramadan intermittent fasting on inflammatory and biochemical biomarkers in males with obesity.
Hassane Zouhal,Reza Bagheri,Damoon Ashtary-Larky,Alexei Wong,Raoua Triki,Anthony C. Hackney,Ismail Laher,Abderraouf Ben Abderrahman +7 more
TL;DR: This study demonstrates that RIF improves systemic inflammation biomarkers in males with obesity and did not negatively affect biomarkers of liver and renal function.
References
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Journal ArticleDOI
Caloric Restriction Delays Disease Onset and Mortality in Rhesus Monkeys
Ricki J. Colman,Rozalyn M. Anderson,Sterling C. Johnson,Erik K. Kastman,Kristopher J. Kosmatka,T. Mark Beasley,David B. Allison,Christina Cruzen,Heather A. Simmons,Joseph W. Kemnitz,Richard Weindruch +10 more
TL;DR: Findings of a 20-year longitudinal adult-onset CR study in rhesus monkeys aimed at filling this critical gap in aging research demonstrate that CR slows aging in a primate species.
Journal ArticleDOI
Risk of dementia in diabetes mellitus: a systematic review
TL;DR: The findings of mechanistic studies suggest that vascular disease and alterations in glucose, insulin, and amyloid metabolism underlie the pathophysiology of dementia, but which of these mechanisms are clinically relevant is unclear.
Journal ArticleDOI
Time-Restricted Feeding without Reducing Caloric Intake Prevents Metabolic Diseases in Mice Fed a High-Fat Diet
Megumi Hatori,Christopher Vollmers,Amir Zarrinpar,Amir Zarrinpar,Luciano DiTacchio,Eric A. Bushong,Shubhroz Gill,Mathias Leblanc,Amandine Chaix,Matthew S. Joens,James A. J. Fitzpatrick,Mark H. Ellisman,Satchidananda Panda +12 more
TL;DR: Mice under tRF consume equivalent calories from HFD as those with ad lib access yet are protected against obesity, hyperinsulinemia, hepatic steatosis, and inflammation and have improved motor coordination.
Journal ArticleDOI
Starvation in man.
TL;DR: In this article, it was shown that decreased levels of active T3 may play a role by sparing otherwise obligated calories by decreasing metabolic needs, but this can be nullified by amino acid or protein supplementation.
Journal ArticleDOI
Metabolic control of mitochondrial biogenesis through the PGC-1 family regulatory network.
TL;DR: The results point to a central role for the PGC-1 family in integrating mitochondrial biogenesis and energy production with many diverse cellular functions.