Journal ArticleDOI
Effects of Intermittent Fasting on Health, Aging, and Disease
Rafael de Cabo,Mark P. Mattson +1 more
TLDR
Effects of Intermittent Fasting on Health and Aging evidence is accumulating that eating in a 6-hour period and fasting for 18 hours can trigger a metabolic switch from glucose-based to ketone-base fasting.Abstract:
Effects of Intermittent Fasting on Health and Aging Evidence is accumulating that eating in a 6-hour period and fasting for 18 hours can trigger a metabolic switch from glucose-based to ketone-base...read more
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Editorial: The model of Ramadan diurnal intermittent fasting: Unraveling the health implications - volume I
TL;DR: The model of Ramadan diurnal intermittent fasting: Unraveling the health implications volume I as mentioned in this paper is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY), provided the original author(s) and the copyright owner(s are credited and that the original publication in this journal is cited.
Posted ContentDOI
Continuous versus Intermittent Nutrition in Pediatric Intensive Care patients (ContInNuPIC): a study protocol for a randomized controlled trial (Preprint)
Karlien Veldscholte,A B Cramer,R. D. de Jonge,Renate D Eveleens,Koen F. M. Joosten,Sascha Verbruggen +5 more
TL;DR: It is hypothesized that intermittent nutrition with the focus on an overnight feeding interruption (‘intermittent fasting’), as compared with 24 hours continuous nutrition, is a feasible and safe strategy for children during critical illness with potential benefits.
Senescence and Diabetes
TL;DR: Diabetes is a clear evident example of premature aging in humans and is a major independent risk factor associated with many diseases that may cluster and occur insidiously and simultaneously.
Journal ArticleDOI
Assessing causality in the association between neurocognitive gains and fasting.
Mona H. AlSheikh,Reem Alatrash,Khaled Aldajani,R. Alkhamis,Manar Alnamlah,S. A. Alhawaj,O. Ahmed,Raidah Albaradie,Shehla Bashir +8 more
TL;DR: Fasting is associated with improvements in cognitive function, and triggers weight loss in human and animal models as mentioned in this paper , and it has increasingly proven worthy of attention from researchers in recent years.
Journal ArticleDOI
Partial Inhibition of Complex I Restores Mitochondrial Morphology and Mitochondria-ER Communication in Hippocampus of APP/PS1 Mice
Jessica D. Panes,Thi Kim Nguyen Nguyen,Huanyao Gao,T. Christensen,Andrea Stojakovic,Sergey Trushin,Jeffrey L. Salisbury,Jorge Fuentealba,Eugenia Trushina +8 more
TL;DR: In this paper , the authors used serial block-face scanning electron microscopy (SBFSEM) and three-dimensional EM reconstructions combined with Western blot analysis and next-generation RNA sequencing to demonstrate that CP2 treatment also restores mitochondrial morphology and mitochondria-endoplasmic reticulum (ER) communication, reducing ER and unfolded protein response (UPR) stress in the APP/PS1 mouse brain.
References
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Caloric Restriction Delays Disease Onset and Mortality in Rhesus Monkeys
Ricki J. Colman,Rozalyn M. Anderson,Sterling C. Johnson,Erik K. Kastman,Kristopher J. Kosmatka,T. Mark Beasley,David B. Allison,Christina Cruzen,Heather A. Simmons,Joseph W. Kemnitz,Richard Weindruch +10 more
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Time-Restricted Feeding without Reducing Caloric Intake Prevents Metabolic Diseases in Mice Fed a High-Fat Diet
Megumi Hatori,Christopher Vollmers,Amir Zarrinpar,Amir Zarrinpar,Luciano DiTacchio,Eric A. Bushong,Shubhroz Gill,Mathias Leblanc,Amandine Chaix,Matthew S. Joens,James A. J. Fitzpatrick,Mark H. Ellisman,Satchidananda Panda +12 more
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Metabolic control of mitochondrial biogenesis through the PGC-1 family regulatory network.
TL;DR: The results point to a central role for the PGC-1 family in integrating mitochondrial biogenesis and energy production with many diverse cellular functions.