Modified Criteria for Radiographic Response Assessment in Glioblastoma Clinical Trials.
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Modifications to the current RANO criteria include suggestions for volumetric response evaluation, use contrast enhanced T1 subtraction maps to increase lesion conspicuity, removal of qualitative non-enhancing tumor assessment requirements and “treatment-agnostic” response assessment rubrics.About:
This article is published in Neurotherapeutics.The article was published on 2017-04-01 and is currently open access. It has received 252 citations till now.read more
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Identifying the Best Machine Learning Algorithms for Brain Tumor Segmentation, Progression Assessment, and Overall Survival Prediction in the BRATS Challenge
Spyridon Bakas,Mauricio Reyes,Andras Jakab,Stefan Bauer,Markus Rempfler,Alessandro Crimi,Russell T. Shinohara,Christoph Berger,Sung Min Ha,Martin Rozycki,Marcel Prastawa,Esther Alberts,Jana Lipkova,John Freymann,John Freymann,Justin Kirby,Justin Kirby,Michel Bilello,Hassan M. Fathallah-Shaykh,Roland Wiest,Jan S. Kirschke,Benedikt Wiestler,Rivka R. Colen,Aikaterini Kotrotsou,Pamela LaMontagne,Daniel S. Marcus,Mikhail Milchenko,Arash Nazeri,Marc-André Weber,Abhishek Mahajan,Ujjwal Baid,Elizabeth R. Gerstner,Dongjin Kwon,Gagan Acharya,Manu Agarwal,M. S. Alam,Alberto Albiol,Antonio Albiol,F. Albiol,Varghese Alex,Nigel M. Allinson,Pedro H. A. Amorim,Abhijit Amrutkar,Ganesh Anand,Simon Andermatt,Tal Arbel,Pablo Arbeláez,Aaron Avery,Muneeza Azmat,B. Pranjal,Wenjia Bai,Subhashis Banerjee,Subhashis Banerjee,Bill Barth,Thomas Batchelder,Kayhan Batmanghelich,Enzo Battistella,Enzo Battistella,Andrew Beers,Mikhail Belyaev,Martin Bendszus,Eze Benson,Jose Bernal,H. N. Bharath,George Biros,Sotirios Bisdas,James M. Brown,Mariano Cabezas,Shilei Cao,Jorge Cardoso,Eric Carver,Adrià Casamitjana,Laura Silvana Castillo,Marcel Catà,Philippe C. Cattin,Albert Cerigues,Vinicius S. Chagas,Siddhartha Chandra,Yi-Ju Chang,Shiyu Chang,Ken Chang,Joseph Chazalon,Shengcong Chen,Wei Chen,Jefferson W. Chen,Zhaolin Chen,Kun Cheng,Ahana Roy Choudhury,Roger Chylla,Albert Clèrigues,Steven Colleman,Ramiro German Rodriguez Colmeiro,Ramiro German Rodriguez Colmeiro,Marc Combalia,Anthony Costa,Xiaomeng Cui,Zhenzhen Dai,Lutao Dai,Laura Alexandra Daza,Eric Deutsch,Changxing Ding,Chao Dong,Shidu Dong,Wojciech Dudzik,Zach Eaton-Rosen,Gary F. Egan,Guilherme Escudero,Théo Estienne,Théo Estienne,Richard M. Everson,Jonathan Fabrizio,Yong Fan,Longwei Fang,Xue Feng,Enzo Ferrante,Lucas Fidon,Martin H. Fischer,Andrew P. French,Naomi Fridman,Huan Fu,David Fuentes,Yaozong Gao,Evan Gates,David T. Gering,Amir Gholami,Willi Gierke,Ben Glocker,Mingming Gong,Mingming Gong,Sandra González-Villà,Thomas Grosges,Yuanfang Guan,Sheng Guo,Sudeep Gupta,Woo-Sup Han,Il Song Han,Konstantin Harmuth,Huiguang He,Aura Hernández-Sabaté,Evelyn Herrmann,Naveen Himthani,Winston H. Hsu,Cheyu Hsu,Hu Xiaojun,Xiaobin Hu,Yan Hu,Yifan Hu,Rui Hua,Teng-Yi Huang,Weilin Huang,Sabine Van Huffel,Quan Huo,Vivek Hv,Khan M. Iftekharuddin,Fabian Isensee,Mobarakol Islam,Aaron S. Jackson,Sachin Jambawalikar,Andrew Jesson,Weijian Jian,Peter H. Jin,V Jeya Maria Jose,V Jeya Maria Jose,Alain Jungo,Bernhard Kainz,Konstantinos Kamnitsas,Po-Yu Kao,Ayush Karnawat,Thomas Kellermeier,Adel Kermi,Kurt Keutzer,Mohamed Tarek Khadir,Mahendra Khened,Philipp Kickingereder,Geena Kim,Nik King,Haley Knapp,Urspeter Knecht,Lisa Kohli,Deren Kong,Xiangmao Kong,Simon Koppers,Avinash Kori,Ganapathy Krishnamurthi,Egor Krivov,Piyush Kumar,Kaisar Kushibar,Dmitrii Lachinov,Dmitrii Lachinov,Tryphon Lambrou,Joon Lee,Chengen Lee,Yuehchou Lee,Matthew C. H. Lee,Szidónia Lefkovits,László Lefkovits,James Levitt,Tengfei Li,Hongwei Li,Wenqi Li,Wenqi Li,Hongyang Li,Xiaochuan Li,Yuexiang Li,Heng Li,Zhenye Li,Xiaoyu Li,Zeju Li,XiaoGang Li,Zheng-Shen Lin,Fengming Lin,Pietro Liò,C Liu,Boqiang Liu,Xiang Liu,Mingyuan Liu,Ju Liu,Luyan Liu,Xavier Lladó,Marc Moreno Lopez,Pablo Ribalta Lorenzo,Zhentai Lu,Lin Luo,Zhigang Luo,Jun Ma,Kai Ma,Thomas Mackie,Anant Madabushi,Issam Mahmoudi,Klaus H. Maier-Hein,Pradipta Maji,C. P. Mammen,Andreas Mang,B.S. Manjunath,M. Marcinkiewicz,Steven McDonagh,Stephen J. McKenna,Richard McKinley,Miriam Mehl,Sachin Mehta,Raghav Mehta,Raphael Meier,Christoph Meinel,Dorit Merhof,Craig H. Meyer,Robert F. Miller,Sushmita Mitra,Aliasgar Moiyadi,David Molina-García,Miguel Monteiro,Grzegorz Mrukwa,Andriy Myronenko,Jakub Nalepa,Thuyen Ngo,Dong Nie,Holly Ning,Chen Niu,Nicholas Nuechterlein,Eric K. Oermann,Arlindo L. Oliveira,Arlindo L. Oliveira,Diego D. C. Oliveira,Arnau Oliver,Alexander F. I. Osman,Yu-Nian Ou,Sebastien Ourselin,Nikos Paragios,Moo Sung Park,Brad Paschke,J. Gregory Pauloski,Kamlesh Pawar,Nick Pawlowski,Linmin Pei,Suting Peng,Silvio M. Pereira,Julián Pérez-Beteta,Víctor M. Pérez-García,Simon Pezold,Bao Pham,Ashish Phophalia,Gemma Piella,G. N. Pillai,Marie Piraud,Maxim Pisov,Anmol Popli,Michael P. Pound,Reza Pourreza,Prateek Prasanna,Vesna Prkovska,Tony P. Pridmore,Santi Puch,Elodie Puybareau,Buyue Qian,Xu Qiao,Martin Rajchl,Swapnil Rane,Michael Rebsamen,Hongliang Ren,Xuhua Ren,Karthik Revanuru,Mina Rezaei,Oliver Rippel,Luis Carlos Rivera,Charlotte Robert,Bruce R. Rosen,Daniel Rueckert,Mohammed Safwan,Mostafa Salem,Joaquim Salvi,Irina Sánchez,Heitor M. Santos,Emmett Sartor,Dawid Schellingerhout,Klaudius Scheufele,Matthew R. Scott,Artur A. Scussel,Sara Sedlar,Juan Pablo Serrano-Rubio,N. Jon Shah,Nameetha Shah,Mazhar Shaikh,B. Uma Shankar,Zeina A. Shboul,Haipeng Shen,Dinggang Shen,Linlin Shen,Haocheng Shen,Varun Shenoy,Feng Shi,Hyung Eun Shin,Hai Shu,Diana M. Sima,Matthew Sinclair,Örjan Smedby,James Snyder,Mohammadreza Soltaninejad,Guidong Song,Mehul Soni,Jean Stawiaski,Shashank Subramanian,Li Sun,Roger Sun,Roger Sun,Jiawei Sun,Kay Sun,Yu Sun,Guoxia Sun,Shuang Sun,Yannick Suter,László Szilágyi,Sanjay N. Talbar,Dacheng Tao,Zhongzhao Teng,Siddhesh Thakur,Meenakshi Thakur,Sameer Tharakan,Pallavi Tiwari,Guillaume Tochon,Tuan Tran,Yuhsiang M. 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Wang,Weichung Wang,Duo Wang,Ruixuan Wang,Yuanyuan Wang,Chunliang Wang,Ning Wen,Xin Wen,Leon Weninger,Wolfgang Wick,Shaocheng Wu,Qiang Wu,Yihong Wu,Yong Xia,Yanwu Xu,Xiaowen Xu,Peiyuan Xu,Tsai-Ling Yang,Xiaoping Yang,Hao-Yu Yang,Junlin Yang,Haojin Yang,Guang Yang,Hongdou Yao,Xujiong Ye,Changchang Yin,Brett Young-Moxon,Jinhua Yu,Xiangyu Yue,Songtao Zhang,Angela Zhang,Kun Zhang,Xuejie Zhang,Lichi Zhang,Xiaoyue Zhang,Yazhuo Zhang,Lei Zhang,Jianguo Zhang,Xiang Zhang,Tianhao Zhang,Sicheng Zhao,Yu Zhao,Xiaomei Zhao,Liang Zhao,Liang Zhao,Yefeng Zheng,Liming Zhong,Chenhong Zhou,Xiaobing Zhou,Fan Zhou,Hongtu Zhu,Jin Zhu,Ying Zhuge,Weiwei Zong,Jayashree Kalpathy-Cramer,Keyvan Farahani,Christos Davatzikos,Koen Van Leemput,Koen Van Leemput,Bjoern H. Menze +438 more
TL;DR: This study assesses the state-of-the-art machine learning methods used for brain tumor image analysis in mpMRI scans, during the last seven instances of the International Brain Tumor Segmentation (BraTS) challenge, i.e., 2012-2018, and investigates the challenge of identifying the best ML algorithms for each of these tasks.
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EANO guidelines on the diagnosis and treatment of diffuse gliomas of adulthood.
Michael Weller,Martin J. van den Bent,Matthias Preusser,Emilie Le Rhun,Jörg C. Tonn,Giuseppe Minniti,Martin Bendszus,Carmen Balana,Olivier Chinot,Linda Dirven,Pim J. French,Monika E. Hegi,Asgeir Store Jakola,Michael Platten,Michael Platten,Patrick Roth,Roberta Rudà,Susan C Short,Marion Smits,Martin J B Taphoorn,Andreas von Deimling,Manfred Westphal,Riccardo Soffietti,Guido Reifenberger,Wolfgang Wick +24 more
TL;DR: These evidence-based guidelines incorporate major changes in diagnostic algorithms based on the 2016 update of the WHO Classification of Tumors of the Central Nervous System as well as on evidence from recent large clinical trials.
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Glioblastoma in adults: a Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) consensus review on current management and future directions
Patrick Y. Wen,Michael Weller,Eudocia Q. Lee,Brian M. Alexander,Jill S. Barnholtz-Sloan,Floris P. Barthel,Tracy T. Batchelor,Ranjit S. Bindra,Susan M. Chang,E. Antonio Chiocca,Timothy F. Cloughesy,John DeGroot,Evanthia Galanis,Mark R. Gilbert,Monika E. Hegi,Craig Horbinski,Raymond Y. Huang,Andrew B. Lassman,Emilie Le Rhun,Michael Lim,Minesh P. Mehta,Ingo K. Mellinghoff,Giuseppe Minniti,David Nathanson,Michael Platten,Matthias Preusser,Patrick Roth,Marc Sanson,David Schiff,Susan C Short,Martin J B Taphoorn,Joerg C. Tonn,Jonathan Tsang,Roel G.W. Verhaak,Andreas von Deimling,Wolfgang Wick,Gelareh Zadeh,David A. Reardon,Kenneth Aldape,Martin J. van den Bent +39 more
TL;DR: Novel therapies such as targeted molecular therapies, agents targeting DNA damage response and metabolism, immunotherapies and viral therapies will be reviewed, as well as the current challenges and future directions for research.
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Response Assessment in Neuro-Oncology Clinical Trials.
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Pseudoprogression of brain tumors
TL;DR: Conventional structural MRI is insufficient for distinguishing pseudoprogression from true progressive disease, and advanced imaging is needed to obtain higher levels of diagnostic certainty, and more studies to date are small, heterogeneous, and retrospective in nature.
References
More filters
Journal ArticleDOI
Radiotherapy plus Concomitant and Adjuvant Temozolomide for Glioblastoma
Roger Stupp,Warren P. Mason,Martin J. van den Bent,Michael Weller,Barbara Fisher,Martin J.B. Taphoorn,Karl Belanger,Alba A. Brandes,Christine Marosi,Ulrich Bogdahn,Jürgen Curschmann,Robert C. Janzer,Samuel K. Ludwin,Thierry Gorlia,Anouk Allgeier,Denis Lacombe,J. Gregory Cairncross,Elizabeth Eisenhauer,René O. Mirimanoff +18 more
TL;DR: The addition of temozolomide to radiotherapy for newly diagnosed glioblastoma resulted in a clinically meaningful and statistically significant survival benefit with minimal additional toxicity.
Journal ArticleDOI
New Guidelines to Evaluate the Response to Treatment in Solid Tumors
Patrick Therasse,Susan G. Arbuck,Elizabeth Eisenhauer,Jantien Wanders,Richard Kaplan,Larry Rubinstein,Jaap Verweij,Martine Van Glabbeke,Allan T. van Oosterom,Michaele C. Christian,S. Gwyther +10 more
TL;DR: A model by which a combined assessment of all existing lesions, characterized by target lesions and nontarget lesions, is used to extrapolate an overall response to treatment is proposed, which is largely validated by the Response Evaluation Criteria in Solid Tumors Group and integrated into the present guidelines.
Journal ArticleDOI
CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2007-2011.
Quinn T. Ostrom,Haley Gittleman,Peter Liao,Chaturia Rouse,Yanwen Chen,Jacqueline Dowling,Yingli Wolinsky,Carol Kruchko,Jill S. Barnholtz-Sloan +8 more
TL;DR: The Central Brain Tumor Registry of the United States (CBTRUS), in collaboration with the Centers for Disease Control and Prevention and National Cancer Institute, is the largest population-based registry focused exclusively on primary brain and other central nervous system (CNS) tumors in the US.
Journal ArticleDOI
Reporting results of cancer treatment.
TL;DR: Recommendations have been developed for standardized approaches to the recording of baseline data relating to the patient, the tumor, laboratory and radiologic data, the reporting of treatment, grading of acute and subacute toxicity, reporting of response, recurrence and disease‐free interval, and reporting results of therapy.
Journal ArticleDOI
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial
Roger Stupp,Monika E. Hegi,Warren P. Mason,Martin J. van den Bent,Martin J.B. Taphoorn,Robert C. Janzer,Samuel K. Ludwin,Anouk Allgeier,Barbara Fisher,Karl Belanger,Peter Hau,Alba A. Brandes,J.M.M. Gijtenbeek,Christine Marosi,Charles J. Vecht,Karima Mokhtari,Pieter Wesseling,Salvador Villà,Elizabeth Eisenhauer,Thierry Gorlia,Michael Weller,Denis Lacombe,J. Gregory Cairncross,René-Olivier Mirimanoff +23 more
TL;DR: Benefits of adjuvant temozolomide with radiotherapy lasted throughout 5 years of follow-up, and a benefit of combined therapy was recorded in all clinical prognostic subgroups, including patients aged 60-70 years.
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