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The i5K initiative: Advancing arthropod genomics for knowledge, human health, agriculture, and the environment

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TLDR
An international effort to guide arthropod genomic efforts, from species prioritization to methodology and informatics is described, which aims to deliver sequences and analytical tools for each of theArthropod branches andEach of the species having beneficial and negative effects on humankind.
Abstract
Insects and their arthropod relatives including mites, spiders, and crustaceans play major roles in the world's terrestrial, aquatic, and marine ecosystems Arthropods compete with humans for food and transmit devastating diseases They also comprise the most diverse and successful branch of metazoan evolution, with millions of extant species Here, we describe an international effort to guide arthropod genomic efforts, from species prioritization to methodology and informatics The 5000 arthropod genomes initiative (i5K) community met formally in 2012 to discuss a roadmap for sequencing and analyzing 5000 high-priority arthropods and is continuing this effort via pilot projects, the development of standard operating procedures, and training of students and career scientists, With university, governmental, and industry support, the i5K Consortium aspires to deliver sequences and analytical tools for each of the arthropod branches and each of the species having beneficial and negative effects on humankind

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Journal ArticleDOI

Understanding Admixture: Haplodiploidy to the Rescue

TL;DR: It is proposed that haplodiploid organisms can help resolve open questions about the genomic consequences of hybridization in natural populations, and the ploidy difference between haploid males and diploid females, the availability of genome-wide male haplotypes, and ongoing cases of admixture make them promising models to improve knowledge.
Journal ArticleDOI

Identification of ecdysteroid receptor-mediated signaling pathways in the hepatopancreas of the red swamp crayfish, Procambarus clarkii.

TL;DR: The hepatopancreas of crustaceans plays an important role in lipid and carbohydrate metabolism, digestion of food, and biogenesis and was characterized for the first time using high-throughput sequencing, producing approximately 41.4 million reads.
Posted ContentDOI

Birth-and-death evolution of the fatty acyl-CoA reductase (FAR) gene family and diversification of cuticular hydrocarbon synthesis in Drosophila

TL;DR: It is suggested that a comparative approach investigating the birth-and-death evolution of gene families can identify candidate genes involved in rapidly diverging traits between species.
Journal ArticleDOI

Alternative Transcription at Venom Genes and Its Role as a Complementary Mechanism for the Generation of Venom Complexity in the Common House Spider.

TL;DR: This work used RNA sequencing of four tissue types in conjunction with the sequenced genome to provide a comprehensive transcriptome annotation and revealed an important role for alternative transcription in generating venom protein complexity and expanded the traditional model of venom evolution.
References
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Journal ArticleDOI

The genome sequence of Drosophila melanogaster

Mark Raymond Adams, +194 more
- 24 Mar 2000 - 
TL;DR: The nucleotide sequence of nearly all of the approximately 120-megabase euchromatic portion of the Drosophila genome is determined using a whole-genome shotgun sequencing strategy supported by extensive clone-based sequence and a high-quality bacterial artificial chromosome physical map.
Journal ArticleDOI

The genome of Tetranychus urticae reveals herbivorous pest adaptations

Miodrag Grbic, +60 more
- 24 Nov 2011 - 
TL;DR: The Tetranychus urticae genome is the smallest known arthropod genome as discussed by the authors, which represents the first complete chelicerate genome for a pest and has been annotated with genes associated with feeding on different hosts.
Journal ArticleDOI

Genome 10K: A Proposal to Obtain Whole-Genome Sequence for 10 000 Vertebrate Species

David Haussler, +69 more
- 01 Nov 2009 - 
TL;DR: A precipitous drop in costs and increase in sequencing efficiency is anticipated, with concomitant development of improved annotation technology, and it is proposed to create a collection of tissue and DNA specimens for 10,000 vertebrate species specifically designated for whole-genome sequencing in the very near future.
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