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The i5K initiative: Advancing arthropod genomics for knowledge, human health, agriculture, and the environment

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TLDR
An international effort to guide arthropod genomic efforts, from species prioritization to methodology and informatics is described, which aims to deliver sequences and analytical tools for each of theArthropod branches andEach of the species having beneficial and negative effects on humankind.
Abstract
Insects and their arthropod relatives including mites, spiders, and crustaceans play major roles in the world's terrestrial, aquatic, and marine ecosystems Arthropods compete with humans for food and transmit devastating diseases They also comprise the most diverse and successful branch of metazoan evolution, with millions of extant species Here, we describe an international effort to guide arthropod genomic efforts, from species prioritization to methodology and informatics The 5000 arthropod genomes initiative (i5K) community met formally in 2012 to discuss a roadmap for sequencing and analyzing 5000 high-priority arthropods and is continuing this effort via pilot projects, the development of standard operating procedures, and training of students and career scientists, With university, governmental, and industry support, the i5K Consortium aspires to deliver sequences and analytical tools for each of the arthropod branches and each of the species having beneficial and negative effects on humankind

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Lepidoptera genomes: current knowledge, gaps and future directions.

TL;DR: With genomic studies quickly becoming integrated with ecological and evolutionary research, the Lepidoptera community will unquestionably benefit from new high-quality reference genomes that are more evenly distributed throughout the order.
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Molluscan genomics: the road so far and the way forward

TL;DR: A historical contextualization of the Genome Revolution in molluscs is provided with a tour de force revision of key research trends observed over the past decade, putting forward that to fully grasp the evolutionary and adaptive roads of this tantalizing group of organisms crucially depends on the full embracement of high-throughput sequencing technologies in the near future.
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Evolutionary Dynamics of Abundant Stop Codon Readthrough

TL;DR: In this paper, comparative genomic evidence across 21 Anopheles mosquitoes and 20 Drosophila species was used to identify evolutionary signatures of conserved, functional readthrough of 353 stop codons.
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Genome engineering: Drosophila melanogaster and beyond

TL;DR: Different ways to perform precise inheritable genome engineering using integrases, recombinases, and DNA nucleases in the Drosophila melanogaster fly model are summarized.
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Genomic data integration for ecological and evolutionary traits in non-model organisms

TL;DR: System biology initiatives such as ENCODE on non-model organisms and their effects on model organisms are studied in detail to help develop system biology initiatives.
References
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Journal ArticleDOI

The genome sequence of Drosophila melanogaster

Mark Raymond Adams, +194 more
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TL;DR: The nucleotide sequence of nearly all of the approximately 120-megabase euchromatic portion of the Drosophila genome is determined using a whole-genome shotgun sequencing strategy supported by extensive clone-based sequence and a high-quality bacterial artificial chromosome physical map.
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The genome of Tetranychus urticae reveals herbivorous pest adaptations

Miodrag Grbic, +60 more
- 24 Nov 2011 - 
TL;DR: The Tetranychus urticae genome is the smallest known arthropod genome as discussed by the authors, which represents the first complete chelicerate genome for a pest and has been annotated with genes associated with feeding on different hosts.
Journal ArticleDOI

Genome 10K: A Proposal to Obtain Whole-Genome Sequence for 10 000 Vertebrate Species

David Haussler, +69 more
- 01 Nov 2009 - 
TL;DR: A precipitous drop in costs and increase in sequencing efficiency is anticipated, with concomitant development of improved annotation technology, and it is proposed to create a collection of tissue and DNA specimens for 10,000 vertebrate species specifically designated for whole-genome sequencing in the very near future.
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