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Open AccessJournal ArticleDOI

Transmission Dynamics and Control of Severe Acute Respiratory Syndrome

TLDR
It is estimated that a single infectious case of SARS will infect about three secondary cases in a population that has not yet instituted control measures, and public-health efforts to reduce transmission are expected to have a substantial impact on reducing the size of the epidemic.
Abstract
Severe acute respiratory syndrome (SARS) is a recently described illness of humans that has spread widely over the past 6 months. With the use of detailed epidemiologic data from Singapore and epidemic curves from other settings, we estimated the reproductive number for SARS in the absence of interventions and in the presence of control efforts. We estimate that a single infectious case of SARS will infect about three secondary cases in a population that has not yet instituted control measures. Public-health efforts to reduce transmission are expected to have a substantial impact on reducing the size of the epidemic.

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Journal ArticleDOI

Combining Clinical and Epidemiologic Features for Early Recognition of SARS

TL;DR: Key epidemiologic risk factors include exposure to settings where SARS activity is suspected or documented, or in the absence of such exposure, Epidemiologic linkage to other persons with pneumonia, or 3) exposure to healthcare settings provide a possible strategic framework for early recognition of SARS.
Journal ArticleDOI

Detecting Differential Transmissibilities That Affect the Size of Self-Limited Outbreaks

TL;DR: This work identifies epidemiological traits of self-limited infections that correlate with transmissibility and evaluates surveillance requirements for detecting a change in the human-to-human transmission of monkeypox since the cessation of cross-protective smallpox vaccination.
Journal ArticleDOI

Estimating the reproduction number from the initial phase of the Spanish flu pandemic waves in Geneva, Switzerland.

TL;DR: This work uses a compartmental model and hospital notification data of the first two waves of the Spanish flu pandemic in Geneva, Switzerland in 1918 to estimate the reproduction number from the early phase of the pandemic waves.
Proceedings ArticleDOI

Pandemic influenza response

TL;DR: A disease spread model is developed that assists in estimating the food need geographically at a given time and an integrated solution approach called the Dynamic Update Approach is developed to build the food distribution network.
Posted ContentDOI

The reproductive number R0 of COVID-19 Based on estimate of a statistical time delay dynamical system

TL;DR: The observed data reported in CCDC's paper is used to estimate distribution of the generation interval of the infection and the simulation results from the time delay dynamic system as well as released data from CCDC to fit the growth rate.
References
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Book

Infectious Diseases of Humans: Dynamics and Control

TL;DR: This book discusses the biology of host-microparasite associations, dynamics of acquired immunity heterogeneity within the human community indirectly transmitted helminths, and the ecology and genetics of hosts and parasites.
Book

A first course in stochastic processes

TL;DR: In this paper, the Basic Limit Theorem of Markov Chains and its applications are discussed and examples of continuous time Markov chains are presented. But they do not cover the application of continuous-time Markov chain in matrix analysis.
Journal ArticleDOI

Seasonal variation in host susceptibility and cycles of certain infectious diseases.

TL;DR: Ample evidence indicates that photoperiod-driven physiologic changes are typical in mammalian species, including some in humans, and underlie human resistance to infectious diseases for large portions of the year and the changes can be identified and modified, the therapeutic and preventive implications may be considerable.
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