Transmission Dynamics and Control of Severe Acute Respiratory Syndrome
Marc Lipsitch,Ted Cohen,Ben S. Cooper,James M. Robins,Stefan Ma,Lyn James,Gowri Gopalakrishna,Suok Kai Chew,Chorh Chuan Tan,Matthew H. Samore,David N. Fisman,Megan Murray +11 more
TLDR
It is estimated that a single infectious case of SARS will infect about three secondary cases in a population that has not yet instituted control measures, and public-health efforts to reduce transmission are expected to have a substantial impact on reducing the size of the epidemic.Abstract:
Severe acute respiratory syndrome (SARS) is a recently described illness of humans that has spread widely over the past 6 months. With the use of detailed epidemiologic data from Singapore and epidemic curves from other settings, we estimated the reproductive number for SARS in the absence of interventions and in the presence of control efforts. We estimate that a single infectious case of SARS will infect about three secondary cases in a population that has not yet instituted control measures. Public-health efforts to reduce transmission are expected to have a substantial impact on reducing the size of the epidemic.read more
Citations
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Journal ArticleDOI
Characterizing the Transmission Dynamics and Control of Ebola Virus Disease
Gerardo Chowell,Hiroshi Nishiura +1 more
TL;DR: Carefully calibrated transmission models have the potential to guide public health officials on the nature and scale of the interventions required to control the ongoing Ebola virus disease epidemic in West Africa.
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Inference for discretely observed stochastic kinetic networks with applications to epidemic modeling
TL;DR: The so-called uniformization representation of a Markov process is applied, in order to efficiently generate appropriate conditional distributions in the Gibbs sampler algorithm, suitable for modeling noisy epidemic data.
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Unpacking β: Within-Host Dynamics and the Evolutionary Ecology of Pathogen Transmission
TL;DR: Generality emerges, however, by “unpacking” β into within- and between-host opportunities for selection, which is illustrated by evolutionary biology of the bacterium Yersinia pestis, which remains highly virulent and is transmitted by multiple routes, including fleas and direct contacts with infected hosts.
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A novel method to prevent secondary exposure of medical and rescue personnel to toxic materials under biochemical hazard conditions using microwave radar and infrared thermography
TL;DR: A toxic condition was induced by intravenous administration of lipopolysaccharide (LPS) in rabbits and the exposure to LPS was determined by linear discriminant analysis using noncontact derived variables.
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Inactivation of airborne influenza virus in the ambient air
TL;DR: This project investigates survival of airborne influenza virus of different sub-types at common room conditions where risk of disease due to microbial transmission could be particularly high, especially at poorly ventilated environments, where viral concentration in the air reaches significant magnitudes.
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