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Open AccessJournal ArticleDOI

Transmission Dynamics and Control of Severe Acute Respiratory Syndrome

TLDR
It is estimated that a single infectious case of SARS will infect about three secondary cases in a population that has not yet instituted control measures, and public-health efforts to reduce transmission are expected to have a substantial impact on reducing the size of the epidemic.
Abstract
Severe acute respiratory syndrome (SARS) is a recently described illness of humans that has spread widely over the past 6 months. With the use of detailed epidemiologic data from Singapore and epidemic curves from other settings, we estimated the reproductive number for SARS in the absence of interventions and in the presence of control efforts. We estimate that a single infectious case of SARS will infect about three secondary cases in a population that has not yet instituted control measures. Public-health efforts to reduce transmission are expected to have a substantial impact on reducing the size of the epidemic.

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Journal ArticleDOI

Sliding mode control of outbreaks of emerging infectious diseases.

TL;DR: It is suggested that proper combinations of threshold densities and control intensities based on threshold policy can either preclude outbreaks or lead the number of infecteds to a previously chosen level.
Posted Content

Simulating SARS: Small-world epidemiological modeling and public health policy assessments

TL;DR: A novel small-world model that makes use of cellular automata with the mirror identities of daily-contact social networks to simulate epidemiological scenarios and can be applied to influenza, enteroviruses, AIDS, and other contagious diseases according to the various needs of health authorities.
Journal ArticleDOI

Generating super-shedders: co-infection increases bacterial load and egg production of a gastrointestinal helminth

TL;DR: This study shows that co-infection may be one of the underlying mechanisms for the often-observed high variance in parasite load and shedding rates, and should thus be taken into consideration for disease management and control.
Journal ArticleDOI

Estimates of serial interval for COVID-19: A systematic review and meta-analysis.

TL;DR: The present review provides sufficient evidence for the estimate of serial interval of COVID-19, which can help in understanding the epidemiology and transmission of the disease.
Journal ArticleDOI

Inserting proteins into the bacterial cytoplasmic membrane using the Sec and YidC translocases.

TL;DR: In this paper, the authors describe the pathways that are used to insert newly synthesized proteins into the cytoplasmic membranes of bacteria, and provide insight into the function of two of the evolutionarily conserved translocases that catalyse this process.
References
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Book

Infectious Diseases of Humans: Dynamics and Control

TL;DR: This book discusses the biology of host-microparasite associations, dynamics of acquired immunity heterogeneity within the human community indirectly transmitted helminths, and the ecology and genetics of hosts and parasites.
Book

A first course in stochastic processes

TL;DR: In this paper, the Basic Limit Theorem of Markov Chains and its applications are discussed and examples of continuous time Markov chains are presented. But they do not cover the application of continuous-time Markov chain in matrix analysis.
Journal ArticleDOI

Seasonal variation in host susceptibility and cycles of certain infectious diseases.

TL;DR: Ample evidence indicates that photoperiod-driven physiologic changes are typical in mammalian species, including some in humans, and underlie human resistance to infectious diseases for large portions of the year and the changes can be identified and modified, the therapeutic and preventive implications may be considerable.
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