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Open AccessJournal ArticleDOI

Transmission Dynamics and Control of Severe Acute Respiratory Syndrome

TLDR
It is estimated that a single infectious case of SARS will infect about three secondary cases in a population that has not yet instituted control measures, and public-health efforts to reduce transmission are expected to have a substantial impact on reducing the size of the epidemic.
Abstract
Severe acute respiratory syndrome (SARS) is a recently described illness of humans that has spread widely over the past 6 months. With the use of detailed epidemiologic data from Singapore and epidemic curves from other settings, we estimated the reproductive number for SARS in the absence of interventions and in the presence of control efforts. We estimate that a single infectious case of SARS will infect about three secondary cases in a population that has not yet instituted control measures. Public-health efforts to reduce transmission are expected to have a substantial impact on reducing the size of the epidemic.

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Posted ContentDOI

Projecting the transmission dynamics of SARS-CoV-2 through the post-pandemic period

TL;DR: It is projected that recurrent wintertime outbreaks of SARS-CoV-2 will probably occur after an initial pandemic wave and the full range of plausible transmission scenarios are summarized.
Journal ArticleDOI

COVID-19: Epidemiology, Evolution, and Cross-Disciplinary Perspectives.

TL;DR: It is proposed, based on the One Health model, that veterinarians and animal specialists should be involved in a cross-disciplinary collaboration in the fight against this epidemic, and suggest a low species barrier for transmission of the virus to farm animals.
Journal ArticleDOI

Transmission dynamics of the COVID-19 outbreak and effectiveness of government interventions: A data-driven analysis.

TL;DR: Evidence from the four‐phase stringent measures showed that it was significant to ensure early detection, early isolation, early treatment, adequate medical supplies, patients’ being admitted to designated hospitals, and comprehensive therapeutic strategy to combat the novel coronavirus.
Journal ArticleDOI

SARS — beginning to understand a new virus

TL;DR: The genomics of the Sars coronavirus (SARS-CoV), its phylogeny, antigenic structure, immune response and potential therapeutic interventions should the SARS epidemic flare up again are reviewed.
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The role of evolution in the emergence of infectious diseases

TL;DR: It is shown that an increase in R0, even when insufficient to generate an epidemic, nonetheless increases the number of subsequently infected individuals and subsequent disease emergence can increase markedly.
References
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Book

Infectious Diseases of Humans: Dynamics and Control

TL;DR: This book discusses the biology of host-microparasite associations, dynamics of acquired immunity heterogeneity within the human community indirectly transmitted helminths, and the ecology and genetics of hosts and parasites.
Book

A first course in stochastic processes

TL;DR: In this paper, the Basic Limit Theorem of Markov Chains and its applications are discussed and examples of continuous time Markov chains are presented. But they do not cover the application of continuous-time Markov chain in matrix analysis.
Journal ArticleDOI

Seasonal variation in host susceptibility and cycles of certain infectious diseases.

TL;DR: Ample evidence indicates that photoperiod-driven physiologic changes are typical in mammalian species, including some in humans, and underlie human resistance to infectious diseases for large portions of the year and the changes can be identified and modified, the therapeutic and preventive implications may be considerable.
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