Transmission Dynamics and Control of Severe Acute Respiratory Syndrome
Marc Lipsitch,Ted Cohen,Ben S. Cooper,James M. Robins,Stefan Ma,Lyn James,Gowri Gopalakrishna,Suok Kai Chew,Chorh Chuan Tan,Matthew H. Samore,David N. Fisman,Megan Murray +11 more
TLDR
It is estimated that a single infectious case of SARS will infect about three secondary cases in a population that has not yet instituted control measures, and public-health efforts to reduce transmission are expected to have a substantial impact on reducing the size of the epidemic.Abstract:
Severe acute respiratory syndrome (SARS) is a recently described illness of humans that has spread widely over the past 6 months. With the use of detailed epidemiologic data from Singapore and epidemic curves from other settings, we estimated the reproductive number for SARS in the absence of interventions and in the presence of control efforts. We estimate that a single infectious case of SARS will infect about three secondary cases in a population that has not yet instituted control measures. Public-health efforts to reduce transmission are expected to have a substantial impact on reducing the size of the epidemic.read more
Citations
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Journal ArticleDOI
Spatio-temporal exploration of SARS epidemic
Arnaud Banos,Javier Lacasa +1 more
TL;DR: A spatio-temporal exploration of national numbers published daily by the World Health Organization during that period of time of SARS, providing original insights on that major epidemic.
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Dynamical modeling of viral spread in spatially distributed populations: stochastic origins of oscillations and density dependence
TL;DR: In this article, a mathematical model for the spread of a viral disease in a population of spatially distributed hosts is described, where the positions of the hosts are randomly generated in a rectangular habitat.
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SARS: an emerging global microbial threat.
TL;DR: Effectively addressing the threat of SARS will require enhanced global infectious disease surveillance, the development of rapid diagnostics, new therapies, and vaccines, implementation of aggressive evidence-based infection control strategies, and effective communication.
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Managing febrile respiratory illnesses during a hypothetical SARS outbreak.
TL;DR: Optimal management of febrile respiratory illnesses during a hypothetical SARS outbreak varies depending on a number of conditions, but increasing influenza vaccination rates would save money and lives.
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Quantifying the value of surveillance data for improving model predictions of lymphatic filariasis elimination.
Edwin Michael,Swarnali Sharma,Morgan E. Smith,Panayiota Touloupou,Federica Giardina,Joaquin M. Prada,Wilma A. Stolk,T. Déirdre Hollingsworth,Sake J. de Vlas +8 more
TL;DR: The development of an analytical framework to quantify the relative values of various longitudinal infection surveillance data collected in field sites undergoing mass drug administrations for calibrating three lymphatic filariasis (LF) models and for improving their predictions of the required durations of drug interventions to achieve parasite elimination in endemic populations is reported.
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