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Open AccessJournal ArticleDOI

Transmission Dynamics and Control of Severe Acute Respiratory Syndrome

TLDR
It is estimated that a single infectious case of SARS will infect about three secondary cases in a population that has not yet instituted control measures, and public-health efforts to reduce transmission are expected to have a substantial impact on reducing the size of the epidemic.
Abstract
Severe acute respiratory syndrome (SARS) is a recently described illness of humans that has spread widely over the past 6 months. With the use of detailed epidemiologic data from Singapore and epidemic curves from other settings, we estimated the reproductive number for SARS in the absence of interventions and in the presence of control efforts. We estimate that a single infectious case of SARS will infect about three secondary cases in a population that has not yet instituted control measures. Public-health efforts to reduce transmission are expected to have a substantial impact on reducing the size of the epidemic.

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Citations
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Journal ArticleDOI

Evaluation of measures to reduce international spread of SARS

TL;DR: While the control response is being developed in a currently uninfected region, border screening can provide up to one week's additional time in which to improve methods for early isolation of cases.
Journal ArticleDOI

How did governmental interventions affect the spread of COVID-19 in European countries?

TL;DR: In this paper, the authors examined how the effective contact rate (ECR), the mean number of daily contacts for an infectious individual to transmit the virus, among European citizens evolved during this wave over the period with implemented measures, disregarding a priori information on governmental measures.

Modeling the invasion and spread of contagious diseases in heterogeneous populations.

TL;DR: This chapter builds on the basic methodologies outlined in the previous chapter to address the question of how to model the invasion and spread of diseases in heterogeneous environments, without making an explicit link to natural selection.
References
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Book

Infectious Diseases of Humans: Dynamics and Control

TL;DR: This book discusses the biology of host-microparasite associations, dynamics of acquired immunity heterogeneity within the human community indirectly transmitted helminths, and the ecology and genetics of hosts and parasites.
Book

A first course in stochastic processes

TL;DR: In this paper, the Basic Limit Theorem of Markov Chains and its applications are discussed and examples of continuous time Markov chains are presented. But they do not cover the application of continuous-time Markov chain in matrix analysis.
Journal ArticleDOI

Seasonal variation in host susceptibility and cycles of certain infectious diseases.

TL;DR: Ample evidence indicates that photoperiod-driven physiologic changes are typical in mammalian species, including some in humans, and underlie human resistance to infectious diseases for large portions of the year and the changes can be identified and modified, the therapeutic and preventive implications may be considerable.
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