Transmission Dynamics and Control of Severe Acute Respiratory Syndrome
Marc Lipsitch,Ted Cohen,Ben S. Cooper,James M. Robins,Stefan Ma,Lyn James,Gowri Gopalakrishna,Suok Kai Chew,Chorh Chuan Tan,Matthew H. Samore,David N. Fisman,Megan Murray +11 more
TLDR
It is estimated that a single infectious case of SARS will infect about three secondary cases in a population that has not yet instituted control measures, and public-health efforts to reduce transmission are expected to have a substantial impact on reducing the size of the epidemic.Abstract:
Severe acute respiratory syndrome (SARS) is a recently described illness of humans that has spread widely over the past 6 months. With the use of detailed epidemiologic data from Singapore and epidemic curves from other settings, we estimated the reproductive number for SARS in the absence of interventions and in the presence of control efforts. We estimate that a single infectious case of SARS will infect about three secondary cases in a population that has not yet instituted control measures. Public-health efforts to reduce transmission are expected to have a substantial impact on reducing the size of the epidemic.read more
Citations
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Monitoring of viable airborne SARS virus in ambient air.
Igor E. Agranovski,A. S. Safatov,Oleg V. Pyankov,Sergeev An,Alexander P. Agafonov,Georgy M Ignatiev,E. I. Ryabchikova,A.I. Borodulin,Artemii A. Sergeev,Hans Wilhelm Doerr,Holger F. Rabenau,Victoria Agranovski +11 more
TL;DR: The new sampling method of direct non-violent collection of viable airborne SARS virus into the appropriate liquid environment was found suitable for monitoring of such stress sensitive virus.
Journal ArticleDOI
Effectiveness of control measures during the SARS epidemic in Beijing: a comparison of the Rt curve and the epidemic curve
TL;DR: The effective reproductive number Rt is estimated for the Beijing SARS epidemic, which represents the average number of secondary cases per primary case on each day of the epidemic and is therefore a measure of the underlying transmission dynamics.
Journal ArticleDOI
Transmissibility of COVID-19 in 11 major cities in China and its association with temperature and humidity in Beijing, Shanghai, Guangzhou, and Chengdu.
TL;DR: The transmissibility of COVID-19 was strong and importance should be attached to the intervention of its transmission especially in Wuhan, according to the correlation between R 0 and weather, the spread of disease will be suppressed as the weather warms.
Journal ArticleDOI
A Nonhomogeneous Agent-Based Simulation Approach to Modeling the Spread of Disease in a Pandemic Outbreak
TL;DR: An agent-based simulation model is proposed that treats each individual as unique, with nonhomogeneous transmission and infection rates correlated to demographic information and behavior, and can be used as a policy-making tool for determining a suitable mitigation strategy.
Journal ArticleDOI
SARS-CoV-2/COVID-19: Evolving Reality, Global Response, Knowledge Gaps, and Opportunities.
Marcin F. Osuchowski,Federico Aletti,Jean-Marc Cavaillon,Stefanie B. Flohé,Evangelos J. Giamarellos-Bourboulis,Markus Huber-Lang,Borna Relja,Tomasz Skirecki,Andrea Szabó,Marc Maegele +9 more
TL;DR: Focus is given on SARS-CoV-2 immunopathogenesis in the context of experimental therapies and preclinical evidence and their applicability in supporting efficacious clinical trial planning and the potential application of translational technology for epidemiological predictions, patient monitoring, and treatment decision-making in COVID-19.
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