Transmission Dynamics and Control of Severe Acute Respiratory Syndrome
Marc Lipsitch,Ted Cohen,Ben S. Cooper,James M. Robins,Stefan Ma,Lyn James,Gowri Gopalakrishna,Suok Kai Chew,Chorh Chuan Tan,Matthew H. Samore,David N. Fisman,Megan Murray +11 more
TLDR
It is estimated that a single infectious case of SARS will infect about three secondary cases in a population that has not yet instituted control measures, and public-health efforts to reduce transmission are expected to have a substantial impact on reducing the size of the epidemic.Abstract:
Severe acute respiratory syndrome (SARS) is a recently described illness of humans that has spread widely over the past 6 months. With the use of detailed epidemiologic data from Singapore and epidemic curves from other settings, we estimated the reproductive number for SARS in the absence of interventions and in the presence of control efforts. We estimate that a single infectious case of SARS will infect about three secondary cases in a population that has not yet instituted control measures. Public-health efforts to reduce transmission are expected to have a substantial impact on reducing the size of the epidemic.read more
Citations
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Posted ContentDOI
Serial interval of novel coronavirus (2019-nCoV) infections
TL;DR: The COVID-19 serial interval is also shorter than the serial interval of severe acute respiratory syndrome (SARS), indicating that calculations made using the SARS serial interval may introduce bias.
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Environmental factors on the SARS epidemic: air temperature, passage of time and multiplicative effect of hospital infection.
TL;DR: SARS transmission appeared to be dependent on seasonal temperature changes and the multiplicative effect of hospital infection and SARS also appeared to retreat naturally over time.
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The modeling of global epidemics: stochastic dynamics and predictability.
TL;DR: A stochastic computational framework for the modeling of the global spreading of infectious diseases that takes advantage of the complete International Air Transport Association 2002 database complemented with census population data is put forward.
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Inflammation Triggered by SARS-CoV-2 and ACE2 Augment Drives Multiple Organ Failure of Severe COVID-19: Molecular Mechanisms and Implications.
Masae Iwasaki,Masae Iwasaki,Junichi Saito,Junichi Saito,Hailin Zhao,Atsuhiro Sakamoto,Kazuyoshi Hirota,Daqing Ma +7 more
TL;DR: This review summarizes the current evidence and understanding of the underlying mechanisms of SARS-CoV-2, ACE2 and inflammation co-mediated multi-organ injury or failure in COVID-19 patients.
References
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