Transmission Dynamics and Control of Severe Acute Respiratory Syndrome
Marc Lipsitch,Ted Cohen,Ben S. Cooper,James M. Robins,Stefan Ma,Lyn James,Gowri Gopalakrishna,Suok Kai Chew,Chorh Chuan Tan,Matthew H. Samore,David N. Fisman,Megan Murray +11 more
TLDR
It is estimated that a single infectious case of SARS will infect about three secondary cases in a population that has not yet instituted control measures, and public-health efforts to reduce transmission are expected to have a substantial impact on reducing the size of the epidemic.Abstract:
Severe acute respiratory syndrome (SARS) is a recently described illness of humans that has spread widely over the past 6 months. With the use of detailed epidemiologic data from Singapore and epidemic curves from other settings, we estimated the reproductive number for SARS in the absence of interventions and in the presence of control efforts. We estimate that a single infectious case of SARS will infect about three secondary cases in a population that has not yet instituted control measures. Public-health efforts to reduce transmission are expected to have a substantial impact on reducing the size of the epidemic.read more
Citations
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Modeling the variations in pediatric respiratory syncytial virus seasonal epidemics
Molly Leecaster,Per H. Gesteland,Tom Greene,Nephi Walton,Adi V. Gundlapalli,Robert T. Rolfs,Carrie L. Byington,Matthew H. Samore +7 more
TL;DR: Examination of empirical relationships among early exponential growth rate, total epidemic size, and timing, and the utility of specific parameters in compartmental models of transmission in accounting for variation among seasonal RSV epidemic curves concluded that exponential growth was somewhat empirically related to seasonal epidemic characteristics.
Journal ArticleDOI
Joint estimation of the basic reproduction number and generation time parameters for infectious disease outbreaks.
TL;DR: It is recommended that, wherever possible, estimation of the basic and effective reproduction numbers should be based on a well-defined epidemic model; moreover, if external information is available then it should be incorporated in a Bayesian analysis.
Journal ArticleDOI
Nanotechnology-Based Approaches for the Detection of SARS-CoV-2
Ritika Gupta,Poonam Sagar,Nitesh Priyadarshi,Sunaina Kaul,Rajat Sandhir,Vikas Rishi,Nitin Kumar Singhal +6 more
TL;DR: In this paper, a nanotechnology-based potential biosensor for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is discussed with particular emphasis on lateral flow assay (LFA), surface enhanced Raman scattering (SERS)-based biosensor, localized surface plasmon resonance (LSPR)-based biometric, electrochemical biosensor and artificial intelligence-based biosensors.
Journal ArticleDOI
Self-propelled pedestrian dynamics model: Application to passenger movement and infection propagation in airplanes
TL;DR: It is found that smaller aircrafts are effective in reducing the contacts between passengers and column wise deplaning and random boarding are found to be two strategies that reduced the number of contacts during passenger movement, and can potentially lower the likelihood of infection spread.
Journal ArticleDOI
The Covid-19 outbreak in Spain. A simple dynamics model, some lessons, and a theoretical framework for control response.
TL;DR: The dynamics of the epidemic in Spain over the whole span is model, and the effectiveness of control measures are studied, to easily estimate the size of the outbreak and the benefit of early intervention.
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