Transmission of SARS-CoV-2 in Domestic Cats.
Peter Halfmann,Masato Hatta,Shiho Chiba,Tadashi Maemura,Shufang Fan,Makoto Takeda,Noriko Kinoshita,Shin ichiro Hattori,Yuko Sakai-Tagawa,Kiyoko Iwatsuki-Horimoto,Masaki Imai,Yoshihiro Kawaoka,Yoshihiro Kawaoka +12 more
TLDR
Coronavirus in Cats SARS-CoV-2 was detected in three cats after they were cohoused with cats that had been experimentally inoculated with the virus.Abstract:
Coronavirus in Cats SARS-CoV-2 was detected in three cats after they were cohoused with cats that had been experimentally inoculated with the virus. Cats may be a silent intermediate host of SARS-C...read more
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Transmission of SARS-CoV-2 on mink farms between humans and mink and back to humans.
Bas B. Oude Munnink,Reina S. Sikkema,David F. Nieuwenhuijse,Robert Jan Molenaar,Emmanuelle Munger,Richard Molenkamp,Arco N. van der Spek,Paulien Tolsma,Ariene Rietveld,Miranda Brouwer,Noortje Bouwmeester-Vincken,Frank Harders,Renate Hakze-van der Honing,Marjolein C.A. Wegdam-Blans,Ruth Bouwstra,Corine H. GeurtsvanKessel,Annemiek A. van der Eijk,Francisca C. Velkers,Lidwien A.M. Smit,Arjan Stegeman,Wim H.M. van der Poel,Marion Koopmans +21 more
TL;DR: The SARS-CoV-2 virus was initially introduced by humans and has since evolved, most likely reflecting widespread circulation among mink in the beginning of the infection period, several weeks before detection.
Journal ArticleDOI
Animal models for COVID-19.
César Muñoz-Fontela,William E. Dowling,Simon G. P. Funnell,Pierre Stéphane Gsell,A. Ximena Riveros-Balta,Randy A. Albrecht,Hanne Leth Andersen,Ralph S. Baric,Miles W. Carroll,Marco Cavaleri,Chuan Qin,Ian Crozier,Kai Dallmeier,Leon de Waal,Emmie de Wit,Leen Delang,Erik D. Dohm,W. Paul Duprex,Darryl Falzarano,Courtney L. Finch,Matthew B. Frieman,Barney S. Graham,Lisa E. Gralinski,Kate Guilfoyle,Bart L. Haagmans,Geraldine A. Hamilton,Amy L. Hartman,Sander Herfst,Suzanne J.F. Kaptein,William B. Klimstra,Ivana Knezevic,Philip R. Krause,Jens H. Kuhn,Roger Le Grand,Mark G. Lewis,Wen-Chun Liu,Pauline Maisonnasse,Anita K. McElroy,Vincent J. Munster,Nadia Oreshkova,Angela L. Rasmussen,Joana Rocha-Pereira,Barry Rockx,Estefanía Rodríguez,Thomas F. Rogers,Francisco J. Salguero,Michael Schotsaert,Koert J. Stittelaar,Hendrik Jan Thibaut,Chien Te K. Tseng,Júlia Vergara-Alert,Martin Beer,Trevor Brasel,Jasper Fuk-Woo Chan,Adolfo García-Sastre,Johan Neyts,Stanley Perlman,Douglas S. Reed,Juergen A. Richt,Chad J. Roy,Joaquim Segalés,Seshadri S. Vasan,Seshadri S. Vasan,Ana Maria Henao-Restrepo,Dan H. Barouch +64 more
TL;DR: The findings of a World Health Organization expert working group that is developing animal models to test vaccines and therapeutic agents for the treatment of COVID-19, and their relevance for preclinical testing, are reviewed.
Journal ArticleDOI
Identification of SARS-CoV-2 spike mutations that attenuate monoclonal and serum antibody neutralization.
Zhuoming Liu,Laura A. VanBlargan,Louis Marie Bloyet,Paul W. Rothlauf,Paul W. Rothlauf,Rita E. Chen,Spencer Stumpf,Haiyan Zhao,John M. Errico,Elitza S. Theel,Mariel J. Liebeskind,Brynn Alford,William Buchser,Ali H. Ellebedy,Daved H. Fremont,Michael S. Diamond,Sean P. J. Whelan +16 more
TL;DR: In this article, a VSV-eGFP-SARS-CoV-2-S chimeric virus was exposed to 19 neutralizing monoclonal antibodies (mAbs) against the receptor-binding domain (RBD) and generated 50 different escape mutants.
Journal ArticleDOI
SARS-CoV-2 infection in farmed minks, the Netherlands, April and May 2020.
Nadia Oreshkova,Robert Jan Molenaar,Sandra Vreman,Frank Harders,Bas B. Oude Munnink,Renate Hakze-van der Honing,Nora M. Gerhards,Paulien Tolsma,Ruth Bouwstra,Reina S. Sikkema,Mirriam G.J. Tacken,Myrna M.T. de Rooij,Eefke Weesendorp,Marc Y. Engelsma,Christianne Bruschke,Lidwien A.M. Smit,Marion Koopmans,Wim H.M. van der Poel,Arjan Stegeman +18 more
TL;DR: Variations in mink-derived viral genomes showed between-mink transmission and no infection link between the farms, and inhalable dust contained viral RNA, indicating possible exposure of workers.
Journal ArticleDOI
Transmission of SARS-CoV-2: A Review of Viral, Host, and Environmental Factors.
TL;DR: This review summarizes current knowledge about the transmission of SARS-CoV-2 and suggests evidence-based policies and practices should incorporate the accumulating knowledge to help educate the public and slow spread of this virus.
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