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Alison Goate
Researcher at Icahn School of Medicine at Mount Sinai
Publications - 781
Citations - 98332
Alison Goate is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Genome-wide association study & Alzheimer's disease. The author has an hindex of 136, co-authored 721 publications receiving 85846 citations. Previous affiliations of Alison Goate include St Mary's Hospital & Brown University.
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Mutant S182(PS-1) genes
Robert Clark,Alison Goate +1 more
TL;DR: In this paper, the authors proposed a method for detecting variant PS-1 genes associated with Alzheimer's disease and methods of detecting the variant genes. But their method was not suitable for the detection of the genes.
Journal ArticleDOI
17q21.31 sub-haplotypes underlying H1-associated risk for Parkinson’s disease are associated with LRRC37A/2 expression in astrocytes
Kathryn R. Bowles,Derian A. Pugh,Yiyuan Liu,Tulsi Patel,Alan E. Renton,Sara Bandres-Ciga,Ziv Gan-Or,Peter Heutink,Ari Siitonen,Sarah Bertelsen,Jonathan D. Cherry,Celeste M. Karch,Steven J. Frucht,Brian H. Kopell,Inga Peter,Alexander W. Charney,Towfique Raj,John F. Crary,Alison Goate +18 more
TL;DR: Parkinson's disease (PD) is genetically associated with the H1 haplotype of the MAPT 17q.21.31 locus, although the causal gene and variants underlying this association have not been identified as mentioned in this paper .
Journal ArticleDOI
The association of polygenic risk for schizophrenia, bipolar disorder, and depression with neural connectivity in adolescents and young adults: examining developmental and sex differences.
Jacquelyn L. Meyers,David B. Chorlian,T. B. Bigdeli,Emma C. Johnson,Fazil Aliev,Arpana Agrawal,Laura Almasy,Andrey P. Anokhin,Howard J. Edenberg,Tatiana Foroud,Alison Goate,Chella Kamarajan,Sivan Kinreich,J. Nurnberger,Ashwini K. Pandey,Gayathri Pandey,M. H. Plawecki,M. H. Plawecki,Jessica E. Salvatore,J. Zhang,A. Fanous,Bernice Porjesz +21 more
TL;DR: Striking differences were observed between men and women throughout development, mapping onto key periods of risk for the onset of psychotic illness and underlining the critical importance of examining sex differences in associations with neuropsychiatric PRS across development.
Journal ArticleDOI
Regional localization and characterization of a DNA segment on the long arm of chromosome 21
David Neil Cooper,S. C. Niemann,John R. Gosden,A. R. Mitchell,Alison Goate,G. S. Rajendran,Dorothy A. Miller,Louis Lim,Jörg Schmidtke +8 more
TL;DR: A human genomic DNA fragment, pAM37 (HGM8; D21S22), was mapped to chromosome 21q2.1- q2.21 by in situ hybridization and will contribute to the linkage mapping of chromosome 21 and will facilitate delineation of the pathological region of Down syndrome.
Journal ArticleDOI
Genome-wide association study of age at onset of Alzheimer's disease
Denise Harold,Paul Hollingworth,Marian L. Hamshere,Peter Holmans,Richard Abraham,Rebecca Sims,Amy Gerrish,Simon Lovestone,Carol Brayne,Michael Gill,Brian A. Lawlor,Peter Passmore,Markus M. Nöthen,Wolfgang Maier,Gill Livingston,Nicola Bass,Alison Goate,Steven G. Younkin,Ammar Al-Chalabi,Rhian Gwilliam,Kevin Morgan,Panos Deloukas,Michael Conlon O'Donovan,Michael John Owen,Julie Williams +24 more
TL;DR: This book aims to provide a chronology of key events in the development of depression and its role in the lives of patients and clinicians from around the world.