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Alison Goate
Researcher at Icahn School of Medicine at Mount Sinai
Publications - 781
Citations - 98332
Alison Goate is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Genome-wide association study & Alzheimer's disease. The author has an hindex of 136, co-authored 721 publications receiving 85846 citations. Previous affiliations of Alison Goate include St Mary's Hospital & Brown University.
Papers
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Improved Protocol for Reproducible Human Cortical Organoids Reveals Early Alterations in Metabolism with MAPT Mutations
Taylor B. Bertucci,Kathryn R. Bowles,Steven Lotz,Le-Yao Qi,Susan K. Goderie,Susan M. Borden,Laura-Maria Oja,K. Lane,Rebecca Chowdhury,Shona Joy,Brigitte L. Arduini,David C. Butler,Heide F Baron,M. Catarina Silva,Stephen J. Haggarty,Celeste M. Karch,Daniel H. Geschwind,Alison Goate,Sally Temple +18 more
TL;DR: In this article , a 96-slitwell method for efficient, scalable, reproducible cortical organoid production from human pluripotent stem cells (hPSCs) was proposed.
Journal ArticleDOI
Cross‐ancestry effect of APOE on cognitive performance
Nadia V. Harerimana,Clara Li,Carolyn W. Zhu,Mary Sano,Hillel Grossman,Alison Goate,Shea J. Andrews +6 more
TL;DR: In this article , the interactive effect of race, ancestry and APOE on episodic memory performance was investigated for Alzheimer's disease in populations of non-European ancestry, with Black and Hispanic adults 1.5 and 2.5 times more likely to develop AD respectively.
Journal ArticleDOI
Genome-wide structural variant analysis identifies risk loci for non-Alzheimer’s dementias
Karri Kaivola,Ruth Chia,Jinhui Ding,Memoona Rasheed,Masashi Fujita,Vilas Menon,Ronald L. Walton,Ryan L. Collins,Kimberley Billingsley,Harrison Brand,Michael E. Talkowski,Xuefang Zhao,Ramita Dewan,Anindita Sinha Ray,Sultana Solaiman,P. Alvarez Jerez,Lakshay Malik,Ted M. Dawson,Liana S. Rosenthal,Marilyn S. Albert,Olga Pletnikova,Juan C. Troncoso,Mario Masellis,Julia Keith,Sandra E. Black,Luigi Ferrucci,Susan M. Resnick,Toshiko Tanaka,Eric J. Topol,Ali Torkamani,Tatiana Foroud,Bernardino Ghetti,John Landers,Mina Ryten,Huw Morris,John Hardy,Letizia Mazzini,Sandra D'Alfonso,Cristina Moglia,Andrea Calvo,Geidy E. Serrano,Thomas G. Beach,Tanis J. Ferman,Neill R. Graff-Radford,Bradley F. Boeve,Zbigniew K. Wszolek,Dennis W. Dickson,Adriano Chiò,David A. Bennett,Philip L. De Jager,Owen A. Ross,Clifton L. Dalgard,J. Raphael Gibbs,Bryan J. Traynor,Anthony R. Soltis,Coralie Viollet,D. Sukumar,Camille Alba,Nathaniel M. Lott,Meila Tuck,Jatinder Singh,Dagmar Bacikova,Xijun Zhang,Daniel Hupalo,A.A. Adeleye,Matthew D. Wilkerson,Harvey B. Pollard,Ziv Gan-Or,Ekaterina Rogaeva,Alexis Brice,Suzanne Lesage,Georgia Xiromerisiou,Antonio Canosa,Giancarlo Logroscino,Gabriele Mora,Patrick May,Daniel Alcolea,Jordi Clarimón,Juan Fortea,Isabel González-Aramburu,Jon Infante,Carmen Lage,Alberto Lleó,Pau Pastor,Pascual Sánchez-Juan,Frances Brett,Dag Aarsland,Safa Al-Sarraj,Johannes Attems,Steve M. Gentleman,Angela Hodges,Seth Love,Ian G. McKeith,Christopher Morris,Laura Palmer,Stuart Pickering-Brown,Alan J. Thomas,Claire Troakes,Matthew J. Barrett,Lynn M. Bekris,Kelley Faber,Margaret E. Flanagan,Alison Goate,David Goldstein,Horacio Kaufmann,Walter A. Kukull,James B. Leverenz,Grisel Lopez,Qinwen Mao,Eliezer Masliah,Edwin S. Monuki,Kathy Newell,José M. Palma,Matthew H. Perkins,Alan E. Renton,Clemens R. Scherzer,Vikram G. Shakkottai,Ellen Sidransky,Nahid Tayebi,Randy Woltjer,Sonja W. Scholz,Robert W. Baloh,Robert A. Bowser,James Broach,William Camu,Johnathan Cooper-Knock,Carsten Drepper,Vivian E. Drory,Travis Dunckley,E. Feldman,Pietro Fratta,Glenn T Gerhard,Summer Gibson,Jonathan D. Glass,Matthew B. Harms,Terry Heiman-Patterson,Lilja Jansson,Janine Kirby,Justin Y. Kwan,Hannu Laaksovirta,Francesco P. Landi,Isabelle Le Ber,Serge Lumbroso,Daniel MacGowan,Nicholas J. Maragakis,Kevin Mouzat,Liisa Myllykangas,Richard W. Orrell,Lyle W. Ostrow,Roger Pamphlett,Erik P. Pioro,Stefan M. Pulst,John Ravits,Wim Robberecht,Jeffrey D. Rothstein,Michael Sendtner,Pamela J. Shaw,Katie C. L. Sidle,Zachary Simmons,Thor D. Stein,David J. Stone,Pentti J. Tienari,Miko Valori,Philip Van Damme,Vivianna M. Van Deerlin,Ludo Van Den Bosch,Lorne Zinman +166 more
TL;DR: In this paper , the role of structural variants, a largely unexplored type of genetic variation, in two non-Alzheimer's dementias, namely Lewy body dementia (LBD) and frontotemporal dementia (FTD)/amyotrophic lateral sclerosis (ALS), was characterized.
Involvement of vimentin in the reverse transformation
TL;DR: The results support the proposed scheme that phosphorylation of cytoskeletal elements initiates a large- scale genetic regulatory action in which a substantial change in the spectrum of genome exposure and sequestration occurs and a function for intermediate filaments in reverse transformation is implied.
Patent
Method for elucidation and detection of polymorphisms, splice variants, and proximal coding mutations using intronic sequences of the alzheimer's S182 gene
John Hardy,Alison Goate +1 more
TL;DR: In this paper, a method of detecting polymorphisms in the S182 gene by detecting mutations in the s182 gene using selected mismatched PCR primers comprising sequences derived from intronic sequences of the S 182 gene is provided.