G
G N Okoli
Researcher at University of Bristol
Publications - 16
Citations - 1124
G N Okoli is an academic researcher from University of Bristol. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 6, co-authored 9 publications receiving 813 citations.
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Journal ArticleDOI
Oral anticoagulants for prevention of stroke in atrial fibrillation: systematic review, network meta-analysis, and cost effectiveness analysis.
José A López-López,Jonathan A C Sterne,Jonathan A C Sterne,Howard Thom,Julian P T Higgins,Julian P T Higgins,Aroon D. Hingorani,G N Okoli,Philippa Davies,Philippa Davies,Pritesh N Bodalia,Pritesh N Bodalia,Peter Bryden,Nicky J Welton,Nicky J Welton,William Hollingworth,Deborah M Caldwell,Jelena Savović,Jelena Savović,Sofia Dias,Chris Salisbury,Diane Eaton,Annya Stephens-Boal,Reecha Sofat +23 more
TL;DR: Apixaban 5 mg twice daily was ranked the highest for most outcomes, and was cost effective compared with warfarin, and the network meta-analysis informs the choice of DOACs for prevention of stroke in patients with atrial fibrillation.
Journal ArticleDOI
Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases A Mendelian Randomization Study
Philip C Haycock,Stephen Burgess,Aayah Nounu,Jie Zheng,G N Okoli,Jack Bowden,Kaitlin H Wade,Nicholas J. Timpson,David M. Evans,Peter Willeit,Abraham Aviv,Tom R. Gaunt,Gibran Hemani,Massimo Mangino,Hayley P Ellis,Kathreena M Kurian,Karen A. Pooley,Rosalind A. Eeles,Jeffrey E. Lee,Shenying Fang,Wei V. Chen,Matthew Law,Lisa Bowdler,Mark M. Iles,Qiong Yang,Bradford B. Worrall,Hugh S. Markus,Rayjean J. Hung,Christopher I. Amos,Amanda B. Spurdle,Deborah J. Thompson,Tracy A. O'Mara,Brian M. Wolpin,Laufey T. Amundadottir,Rachael Z. Stolzenberg-Solomon,Antonia Trichopoulou,N. Charlotte Onland-Moret,Eiliv Lund,Eric J. Duell,Federico Canzian,Gianluca Severi,Kim Overvad,Marc J. Gunter,Rosario Tumino,Ulrika Svenson,Andre M. van Rij,Annette F. Baas,Matthew J. Bown,Nilesh J. Samani,Femke N G van t'Hof,Gerard Tromp,Gregory T. Jones,Helena Kuivaniemi,James R. Elmore,Mattias Johansson,James McKay,Ghislaine Scelo,Robert Carreras-Torres,Valerie Gaborieau,Paul Brennan,Paige M. Bracci,Rachel E. Neale,Sara H. Olson,Steven Gallinger,Donghui Li,Gloria M. Petersen,Harvey A. Risch,Alison P. Klein,Jiali Han,Christian C. Abnet,Neal D. Freedman,Philip R. Taylor,John M. Maris,Katja K.H. Aben,Lambertus A. Kiemeney,Sita H. Vermeulen,John K. Wiencke,Kyle M. Walsh,Margaret Wrensch,Terri Rice,Clare Turnbull,Kevin Litchfield,Lavinia Paternoster,Marie Standl,Gonçalo R. Abecasis,John Paul SanGiovanni,Yong Li,Vladan Mijatovic,Yadav Sapkota,Siew-Kee Low,Krina T. Zondervan,Grant W. Montgomery,Dale R. Nyholt,David A. van Heel,Karen A. Hunt,Dan E. Arking,Foram N. Ashar,Nona Sotoodehnia,Daniel Woo,Jonathan Rosand,Mary E. Comeau,W. Mark Brown,Edwin K. Silverman,John E. Hokanson,Michael H. Cho,Jennie Hui,Manuel A. R. Ferreira,Philip J. Thompson,Alanna C. Morrison,Janine F. Felix,Nicholas L. Smith,Angela M. Christiano,Lynn Petukhova,Regina C. Betz,Xing Fan,Xuejun Zhang,Caihong Zhu,Carl D. Langefeld,Susan D. Thompson,Feijie Wang,Xu Lin,David A. Schwartz,Tasha E. Fingerlin,Jerome I. Rotter,Mary Frances Cotch,Richard A. Jensen,Matthias Munz,Henrik Dommisch,Arne S. Schaefer,Fang Han,Hanna Ollila,Ryan P. Hillary,Omar M. E. Albagha,Stuart H. Ralston,Chenjie Zeng,Wei Zheng,Xiao-Ou Shu,André Reis,Steffen Uebe,Ulrike Hüffmeier,Yoshiya Kawamura,Takeshi Otowa,Tsukasa Sasaki,Martin L. Hibberd,Sonia Davila,Gang Xie,Katherine A. Siminovitch,Jin-Xin Bei,Yi Xin Zeng,Asta Försti,Bowang Chen,Stefano Landi,Andre Franke,Annegret Fischer,David Ellinghaus,Carlos Flores,Imre Noth,Shwu-Fan Ma,Jia Nee Foo,Jianjun Liu,Jong-Won Kim,David G. Cox,Olivier Delattre,Olivier Mirabeau,Christine F. Skibola,Clara S. Tang,Merce Garcia-Barcelo,Kai-Ping Chang,Wen-Hui Su,Yu-Sun Chang,Nicholas G. Martin,Scott D. Gordon,Tracey D. Wade,Chaeyoung Lee,Michiaki Kubo,Pei-Chieng Cha,Yusuke Nakamura,Daniel Levy,Masayuki Kimura,Shih-Jen Hwang,Steven C. Hunt,Tim D. Spector,Nicole Soranzo,Ani Manichaikul,R. Graham Barr,Bratati Kahali,Elizabeth K. Speliotes,Laura M. Yerges-Armstrong,Ching-Yu Cheng,Jost B. Jonas,Tien Yin Wong,Isabella Fogh,Kuang Lin,John Powell,Kenneth Rice,Caroline L Relton,Richard M. Martin,George Davey Smith +197 more
TL;DR: It is likely that longer telomeres increase risk for several cancers but reduce risk for some non-neoplastic diseases, including cardiovascular diseases, as well as single nucleotide polymorphisms (SNPs) that are strongly associated with telomere length in the general population.
Journal ArticleDOI
Oral anticoagulants for primary prevention, treatment and secondary prevention of venous thromboembolic disease, and for prevention of stroke in atrial fibrillation: systematic review, network meta-analysis and cost-effectiveness analysis
Jonathan A C Sterne,Pritesh N Bodalia,Peter Bryden,Philippa Davies,José A López-López,G N Okoli,Howard Thom,Deborah M Caldwell,Sofia Dias,Diane Eaton,Julian P T Higgins,William Hollingworth,Chris Salisbury,Jelena Savović,Reecha Sofat,Annya Stephens-Boal,Nicky J Welton,Aroon D. Hingorani +17 more
TL;DR: For acute treatment and secondary prevention of VTE, there is little evidence that NOACs offer an efficacy advantage over warfarin, but the risk of bleeding complications was lower for someNOACs than for warfarIn, and cost-effectiveness was lower than for other interventions.
Journal ArticleDOI
Screening strategies for atrial fibrillation: a systematic review and cost-effectiveness analysis.
Nicky J Welton,Alexandra McAleenan,Howard Thom,Philippa Davies,William Hollingworth,Julian P T Higgins,G N Okoli,Jonathan A C Sterne,Gene Feder,Diane Eaton,Aroon D. Hingorani,Christopher G. Fawsitt,Trudie Lobban,Peter Bryden,Alison Richards,Reecha Sofat +15 more
TL;DR: A systematic review of the diagnostic test accuracy (DTA) of screening tests for AF and an economic model to compare the cost-effectiveness of different screening strategies were developed, found systematic opportunistic screening was more likely to be cost-effective than systematic population screening.
Journal ArticleDOI
Control of carbapenemase-producing Enterobacteriaceae outbreaks in acute settings: an evidence review.
Clare E French,Caroline Coope,Caroline Coope,Lucy Conway,Lucy Conway,Julian P T Higgins,Janet McCulloch,G N Okoli,Bharat Patel,Isabel Oliver,Isabel Oliver +10 more
TL;DR: A systematic search of MEDLINE and EMBASE databases, abstract lists for key conferences and reference lists of key reviews was undertaken, and information on unpublished outbreaks was sought for 2000-2015 as discussed by the authors.