scispace - formally typeset
J

Johanna I. Kiiski

Researcher at University of Helsinki

Publications -  22
Citations -  3621

Johanna I. Kiiski is an academic researcher from University of Helsinki. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 14, co-authored 20 publications receiving 2703 citations. Previous affiliations of Johanna I. Kiiski include Bashkir State University & Helsinki University Central Hospital.

Papers
More filters
Journal ArticleDOI

Association analysis identifies 65 new breast cancer risk loci

Kyriaki Michailidou, +396 more
- 02 Nov 2017 - 
TL;DR: A genome-wide association study of breast cancer in 122,977 cases and 105,974 controls of European ancestry and 14,068 cases and 13,104 controls of East Asian ancestry finds that heritability of Breast cancer due to all single-nucleotide polymorphisms in regulatory features was 2–5-fold enriched relative to the genome- wide average.
Journal ArticleDOI

RAD51B in Familial Breast Cancer

Liisa M. Pelttari, +115 more
- 05 May 2016 - 
TL;DR: It is suggested that loss-of-function mutations in RAD 51B are rare, but common variation at the RAD51B region is significantly associated with familial breast cancer risk.
Journal ArticleDOI

Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes

Nasim Mavaddat, +310 more
- 03 Jan 2019 - 
TL;DR: This PRS, optimized for prediction of estrogen receptor (ER)-specific disease, from the largest available genome-wide association dataset is developed and empirically validated and is a powerful and reliable predictor of breast cancer risk that may improve breast cancer prevention programs.
Journal ArticleDOI

Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer

Catherine M. Phelan, +443 more
- 01 May 2017 - 
TL;DR: Integrated analyses of genes and regulatory biofeatures at each locus predicted candidate susceptibility genes, including OBFC1, a new candidate susceptibility gene for low-grade and borderline serous EOC.
Journal ArticleDOI

Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.

Roger L. Milne, +512 more
- 23 Oct 2017 - 
TL;DR: A genome-wide association study (GWAS) of predominantly estrogen receptor (ER)-positive disease and BRCA1 mutation carrier GWAS observed consistent associations with ER-negative disease for 105 susceptibility variants identified by other studies, which explain approximately 16% of the familial risk of this breast cancer subtype.