Loic Le Marchand

TL;DR: This work builds a genetic map measuring the probability of crossing over at each position in the genome, based on about 2.1 million crossovers in 30,000 unrelated African Americans, and identifies about 2,500 recombination hotspots that are active in people of West African ancestry but nearly inactive in Europeans.

TL;DR: In this article, the authors used stepwise linear regression and polytomous logistic regression to identify persons at risk for low vitamin D status for both clinical and research purposes, and found significant positive and significant inverse correlates of 25(OH)D included male sex, summer blood draw, vigorous physical activity, vitamin D intake, fish intake, multivitamin use, and calcium supplement use.

TL;DR: There is strong evidence that adult height is a risk factor for breast cancer in women and certain genetic factors and biological pathways affecting adult height have an important role in the etiology of breast cancer.

TL;DR: Common genetic variation in these two genes might play at best a limited role in breast and prostate cancers.

TL;DR: Data support the clinical significance of the CHRNA5 variant rs16969968, which predicts delayed smoking cessation and an earlier age of lung cancer diagnosis in this meta-analysis, and underscore the potential clinical and public health importance of this variant.