Showing papers by "Lancaster University published in 2014"
University of Strathclyde1, Lancaster University2, University of Manchester3, University of Illinois at Urbana–Champaign4, University of Central Lancashire5, Robert Koch Institute6, University of Reims Champagne-Ardenne7, Keele University8, University of Illinois at Chicago9, Monash University, Clayton campus10
TL;DR: This manuscript brings together some of the leaders in this field to allow the standardization of methods and procedures for adapting a multistage approach to a methodology that can be applied to a variety of cell biological questions or used within a clinical setting for disease screening or diagnosis.
Abstract: IR spectroscopy is an excellent method for biological analyses. It enables the nonperturbative, label-free extraction of biochemical information and images toward diagnosis and the assessment of cell functionality. Although not strictly microscopy in the conventional sense, it allows the construction of images of tissue or cell architecture by the passing of spectral data through a variety of computational algorithms. Because such images are constructed from fingerprint spectra, the notion is that they can be an objective reflection of the underlying health status of the analyzed sample. One of the major difficulties in the field has been determining a consensus on spectral pre-processing and data analysis. This manuscript brings together as coauthors some of the leaders in this field to allow the standardization of methods and procedures for adapting a multistage approach to a methodology that can be applied to a variety of cell biological questions or used within a clinical setting for disease screening or diagnosis. We describe a protocol for collecting IR spectra and images from biological samples (e.g., fixed cytology and tissue sections, live cells or biofluids) that assesses the instrumental options available, appropriate sample preparation, different sampling modes as well as important advances in spectral data acquisition. After acquisition, data processing consists of a sequence of steps including quality control, spectral pre-processing, feature extraction and classification of the supervised or unsupervised type. A typical experiment can be completed and analyzed within hours. Example results are presented on the use of IR spectra combined with multivariate data processing.
1,340 citations
TL;DR: The first definition of palliative care in dementia based on evidence and consensus is provided, a framework to provide guidance for clinical practice, policy and research.
Abstract: Background: Dementia is a life-limiting disease without curative treatments. Patients and families may need palliative care specific to dementia. Aim: To define optimal palliative care in dementia. Methods: Five-round Delphi study. Based on literature, a core group of 12 experts from 6 countries drafted a set of core domains with salient recommendations for each domain. We invited 89 experts from 27 countries to evaluate these in a two-round online survey with feedback. Consensus was determined according to predefined criteria. The fourth round involved decisions by the core team, and the fifth involved input from the European Association for Palliative Care. Results: A total of 64 (72%) experts from 23 countries evaluated a set of 11 domains and 57 recommendations. There was immediate and full consensus on the following eight domains, including the recommendations: person-centred care, communication and shared decision-making; optimal treatment of symptoms and providing comfort (these two identified as central to care and research); setting care goals and advance planning; continuity of care; psychosocial and spiritual support; family care and involvement; education of the health care team; and societal and ethical issues. After revision, full consensus was additionally reached for prognostication and timely recognition of dying. Recommendations on nutrition and dehydration (avoiding overly aggressive, burdensome or futile treatment) and on dementia stages in relation to care goals (applicability of palliative care) achieved moderate consensus. Conclusion: We have provided the first definition of palliative care in dementia based on evidence and consensus, a framework to provide guidance for clinical practice, policy and research.
709 citations
TL;DR: In this article, the authors show that enabling camera self-calibration as part of the bundle adjustment process inherently leads to erroneous radial distortion estimates and associated digital elevation models (DEMs).
Abstract: High resolution digital elevation models (DEMs) are increasingly produced from photographs acquired with consumer cameras, both from the ground and from unmanned aerial vehicles (UAVs). However, although such DEMs may achieve centimetric detail, they can also display systematic broad-scale error that estricts their wider use. Such errors which, in typical UAV data are expressed as a vertical ‘doming’ of the surface, result from a combination of near-parallel imaging directions and inaccurate correction of radial lens distortion. Using simulations of multi-image networks with near-parallel viewing directions, we show that enabling camera self-calibration as part of the bundle adjustment process inherently leads to erroneous radial distortion estimates and associated DEM error. This effect is relevant whether a traditional photogrammetric or newer structure-from-motion (SfM) approach is used, but errors are expected to be more pronounced in SfM-based DEMs, for which use of control and check point measurements are typically more limited. Systematic DEM error can be significantly reduced by the additional capture and inclusion of oblique images in the image network; we provide practical flight plan solutions for fixed wing or rotor-based UAVs that, in the absence of control points, can reduce DEM error by up to two orders of magnitude. The magnitude of doming error shows a linear relationship with radial distortion and we show how characterisation of this relationship allows an improved distortion estimate and, hence, existing datasets to be optimally reprocessed. Although focussed on UAV surveying, our results are also relevant to ground-based image capture.
656 citations
University of Minnesota1, University of Maryland, College Park2, Iowa State University3, University of Oldenburg4, Utah State University5, Spanish National Research Council6, Wake Forest University7, University of Washington8, United States Department of Agriculture9, Colorado State University10, Michigan State University11, Trinity College, Dublin12, University of Queensland13, University of Toronto14, Lanzhou University15, University of California, San Diego16, Imperial College London17, University of Wisconsin-Madison18, University of Colorado Boulder19, United States Geological Survey20, Queensland University of Technology21, University of North Carolina at Chapel Hill22, University of Oxford23, University of Nebraska–Lincoln24, University of California, Berkeley25, University of Illinois at Urbana–Champaign26, University of Guelph27, University of Kentucky28, University of Melbourne29, Oregon State University30, Commonwealth Scientific and Industrial Research Organisation31, Swiss Federal Institute for Forest, Snow and Landscape Research32, Lancaster University33, Duke University34, University of California, Davis35
TL;DR: Testing the hypothesis that herbaceous plant species losses caused by eutrophication may be offset by increased light availability due to herbivory demonstrates that nutrients and herbivores can serve as counteracting forces to control local plant diversity through light limitation, independent of site productivity, soil nitrogen, herbivore type and climate.
Abstract: Human alterations to nutrient cycles and herbivore communities are affecting global biodiversity dramatically. Ecological theory predicts these changes should be strongly counteractive: nutrient addition drives plant species loss through intensified competition for light, whereas herbivores prevent competitive exclusion by increasing ground-level light, particularly in productive systems. Here we use experimental data spanning a globally relevant range of conditions to test the hypothesis that herbaceous plant species losses caused by eutrophication may be offset by increased light availability due to herbivory. This experiment, replicated in 40 grasslands on 6 continents, demonstrates that nutrients and herbivores can serve as counteracting forces to control local plant diversity through light limitation, independent of site productivity, soil nitrogen, herbivore type and climate. Nutrient addition consistently reduced local diversity through light limitation, and herbivory rescued diversity at sites where it alleviated light limitation. Thus, species loss from anthropogenic eutrophication can be ameliorated in grasslands where herbivory increases ground-level light.
639 citations
TL;DR: The IoT experimentation facility described in this paper is conceived to provide a suitable platform for large scale experimentation and evaluation of IoT concepts under real-life conditions to influence the definition and specification of Future Internet architecture design.
622 citations
TL;DR: In this article, the dispersion of the valence and conduction bands at their extrema (the $K, $Q, $Gamma, and $M$ points of the hexagonal Brillouin zone) in atomic crystals of semiconducting monolayer transition metal dichalcogenides is described.
Abstract: We present $\mathbf{k}\cdotp\mathbf{p}$ Hamiltonians parametrised by {\it ab initio} density functional theory calculations to describe the dispersion of the valence and conduction bands at their extrema (the $K$, $Q$, $\Gamma$, and $M$ points of the hexagonal Brillouin zone) in atomic crystals of semiconducting monolayer transition metal dichalcogenides. We review the parametrisation of the essential parts of the $\mathbf{k}\cdotp\mathbf{p}$ Hamiltonians for MoS$_2$, MoSe$_2$, WS$_2$, and WSe$_2$, including the spin-splitting and spin-polarisation of the bands, and we discuss the vibrational properties of these materials. We then use $\mathbf{k}\cdotp\mathbf{p}$ theory to analyse optical transitions in two-dimensional transition metal dichalcogenides over a broad spectral range that covers the Van Hove singularities in the band structure (the $M$ points). We also discuss the visualisation of scanning tunnelling microscopy maps.
618 citations
TL;DR: The proposals introduce new species and genera into both subfamilies, resolve one misclassified species, and improve taxonomic clarity by employing a series of systematic changes.
Abstract: A set of proposals to rationalize and extend the taxonomy of the family Parvoviridae is currently under review by the International Committee on Taxonomy of Viruses (ICTV). Viruses in this family infect a wide range of hosts, as reflected by the longstanding division into two subfamilies: the Parvovirinae, which contains viruses that infect vertebrate hosts, and the Densovirinae, encompassing viruses that infect arthropod hosts. Using a modified definition for classification into the family that no longer demands isolation as long as the biological context is strong, but does require a near-complete DNA sequence, 134 new viruses and virus variants were identified. The proposals introduce new species and genera into both subfamilies, resolve one misclassified species, and improve taxonomic clarity by employing a series of systematic changes. These include identifying a precise level of sequence similarity required for viruses to belong to the same genus and decreasing the level of sequence similarity required for viruses to belong to the same species. These steps will facilitate recognition of the major phylogenetic branches within genera and eliminate the confusion caused by the near-identity of species and viruses. Changes to taxon nomenclature will establish numbered, non-Latinized binomial names for species, indicating genus affiliation and host range rather than recapitulating virus names. Also, affixes will be included in the names of genera to clarify subfamily affiliation and reduce the ambiguity that results from the vernacular use of “parvovirus” and “densovirus” to denote multiple taxon levels.
570 citations
TL;DR: In this paper, the use of modern 3D photo-based surface reconstruction techniques for high fidelity surveys of trenches, rock exposures and hand specimens is discussed, highlighting their potential for paleoseismology and structural geology.
548 citations
TL;DR: In this article, the authors provide guidelines for choosing the case study design, defining the unit of analysis, selecting cases (sampling), collecting information, analysing information, presenting results and ensuring validity and reliability in research findings.
545 citations
TL;DR: The T2K experiment has observed electron neutrino appearance in a muon neutrinos beam produced 295 km from the Super-Kamiokande detector with a peak energy of 0.6 GeV, corresponding to a significance of 7.3σ.
Abstract: The T2K experiment has observed electron neutrino appearance in a muon neutrino beam produced 295 km from the Super-Kamiokande detector with a peak energy of 0.6 GeV. A total of 28 electron neutrino events were detected with an energy distribution consistent with an appearance signal, corresponding to a significance of 7.3 sigma when compared to 4.92 +/- 0.55 expected background events. In the Pontecorvo-Maki-Nakagawa-Sakata mixing model, the electron neutrino appearance signal depends on several parameters including three mixing angles theta(12), theta(23), theta(13), a mass difference vertical bar Delta m(32)(2)vertical bar and a CP violating phase delta(CP). In this neutrino oscillation scenario, assuming vertical bar Delta m(32)(2)vertical bar = 2.4 x 10(-3) eV(2), sin theta(2)(23) = 0.5, and vertical bar Delta m(32)(2)vertical bar > 0 (vertical bar Delta m(32)(2)vertical bar <0), a best- fit value of sin2 theta(2)(13) = 0.140(- 0.032)(+0.038) (0.170(-0.037)(+0.045)) is obtained at delta(CP) = 0. When combining the result with the current best knowledge of oscillation parameters including the world average value of theta(13) from reactor experiments, some values of delta(CP) are disfavored at the 90% C. L.
TL;DR: In this paper, the authors develop an alternative approach, viewing energy supply and energy demand as part of the ongoing reproduction of bundles and complexes of social practice, and show how social-theoretical commitments influence the ways in which problems like those of reducing carbon emissions are framed and addressed.
Abstract: Energy has an ambivalent status in social theory, variously figuring as a driver or an outcome of social and institutional change, or as something that is woven into the fabric of society itself. In this article the authors consider the underlying models on which different approaches depend. One common strategy is to view energy as a resource base, the management and organization of which depends on various intersecting systems: political, economic and technological. This is not the only route to take. The authors develop an alternative approach, viewing energy supply and energy demand as part of the ongoing reproduction of bundles and complexes of social practice. In articulating and comparing these two positions they show how social-theoretical commitments influence the ways in which problems like those of reducing carbon emissions are framed and addressed. Whereas theories of practice highlight basic questions about what energy is for, these issues are routinely and perhaps necessarily obscured by those who see energy as an abstract resource that structures or that is structured by a range of interlocking social systems.
SupAgro1, New York University2, University of California, San Diego3, Agro ParisTech4, University of North Texas5, Lancaster University6, University of Missouri7, University of Würzburg8, Chinese Academy of Sciences9, University of Copenhagen10, University of Vermont11, University of Angers12, University of Bern13, Academia Sinica14
TL;DR: The phylogenetic tree was used to determine a unified nomenclature of this family named NPF, for NRT1/PTR FAMILY, and it is proposed that the members should be named accordingly: NPFX.
TL;DR: This paper mainly focuses on demand side management and demand response, including drivers and benefits, shiftable load scheduling methods and peak shaving techniques, and a novel electricity demand control technique using real-time pricing is proposed.
TL;DR: It is demonstrated how careful alignment of the crystallographic orientation of two graphene electrodes separated by a layer of hexagonal boron nitride in a transistor device can achieve resonant tunnelling with conservation of electron energy, momentum and, potentially, chirality.
Abstract: Recent developments in the technology of van der Waals heterostructures1, 2 made from two-dimensional atomic crystals3, 4 have already led to the observation of new physical phenomena, such as the metal–insulator transition5 and Coulomb drag6, and to the realization of functional devices, such as tunnel diodes7, 8, tunnel transistors9, 10 and photovoltaic sensors11. An unprecedented degree of control of the electronic properties is available not only by means of the selection of materials in the stack12, but also through the additional fine-tuning achievable by adjusting the built-in strain and relative orientation of the component layers13, 14, 15, 16, 17. Here we demonstrate how careful alignment of the crystallographic orientation of two graphene electrodes separated by a layer of hexagonal boron nitride in a transistor device can achieve resonant tunnelling with conservation of electron energy, momentum and, potentially, chirality. We show how the resonance peak and negative differential conductance in the device characteristics induce a tunable radiofrequency oscillatory current that has potential for future high-frequency technology.
TL;DR: Dramatic advance has been made in the anion-templated synthesis of macrocycles and interlocked molecular architectures, while the study of transmembrane anion transporters has flourished from almost nothing into a rapidly maturing field of research.
Abstract: Since the start of this millennium, remarkable progress in the binding and sensing of anions has been taking place, driven in part by discoveries in the use of hydrogen bonding, as well as the previously under-exploited anion–π interactions and halogen bonding. However, anion supramolecular chemistry has developed substantially beyond anion recognition, and now encompasses a diverse range of disciplines. Dramatic advance has been made in the anion-templated synthesis of macrocycles and interlocked molecular architectures, while the study of transmembrane anion transporters has flourished from almost nothing into a rapidly maturing field of research. The supramolecular chemistry of anions has also found real practical use in a variety of applications such as catalysis, ion extraction, and the use of anions as stimuli for responsive chemical systems.
TL;DR: A large research programme to examine culture and behaviour in the English National Health Service identified many ‘bright spots’ of excellent caring and practice and high-quality innovation across the NHS, but also considerable inconsistency.
Abstract: Background Problems of quality and safety persist in health systems worldwide. We conducted a large research programme to examine culture and behaviour in the English National Health Service (NHS). Methods Mixed-methods study involving collection and triangulation of data from multiple sources, including interviews, surveys, ethnographic case studies, board minutes and publicly available datasets. We narratively synthesised data across the studies to produce a holistic picture and in this paper present a highlevel summary. Results We found an almost universal desire to provide the best quality of care. We identified many ‘bright spots’ of excellent caring and practice and high-quality innovation across the NHS, but also considerable inconsistency. Consistent achievement of high-quality care was challenged by unclear goals, overlapping priorities that distracted attention, and compliance-oriented bureaucratised management. The institutional and regulatory environment was populated by multiple external bodies serving different but overlapping functions. Some organisations found it difficult to obtain valid insights into the quality of the care they provided. Poor organisational and information systems sometimes left staff struggling to deliver care effectively and disempowered them from initiating improvement. Good staff support and management were also highly variable, though they were fundamental to culture and were directly related to patient experience, safety and quality of care. Conclusions Our results highlight the importance of clear, challenging goals for high-quality care. Organisations need to put the patient at the centre of all they do, get smart intelligence, focus on improving organisational systems, and nurture caring cultures by ensuring that staff feel valued, respected, engaged and supported.
University of Wollongong1, University of Manchester2, University of Cambridge3, Queen's University Belfast4, Erasmus University Rotterdam5, Autonomous University of Barcelona6, King's College London7, University of London8, University of Vienna9, Concordia University10, University of Sussex11, University of Trieste12, Monash University13, University of Wisconsin-Madison14, Australian National University15, University of New South Wales16, New York University17, University of Sydney18, Institute for Advanced Study19, Royal Institute of Technology20, Columbia University21, Aberystwyth University22, Lancaster University23
TL;DR: The authors make the case for a richer conception predicated on broader intellectual engagement and identify some preconditions for its practical fulfilment, and suggest that interdisciplinary dialogue should engender plural representations of Earth's present and future that are reflective of divergent human values and aspirations.
Abstract: Calls for more broad-based, integrated, useful knowledge now abound in the world of global environmental change science. They evidence many scientists' desire to help humanity confront the momentous biophysical implications of its own actions. But they also reveal a limited conception of social science and virtually ignore the humanities. They thereby endorse a stunted conception of 'human dimensions' at a time when the challenges posed by global environmental change are increasing in magnitude, scale and scope. Here, we make the case for a richer conception predicated on broader intellectual engagement and identify some preconditions for its practical fulfilment. Interdisciplinary dialogue, we suggest, should engender plural representations of Earth's present and future that are reflective of divergent human values and aspirations. In turn, this might insure publics and decision-makers against overly narrow conceptions of what is possible and desirable as they consider the profound questions raised by global environmental change.
TL;DR: Whether the effect of ERPs on patient outcomes varies across surgical specialties or with the design of individual programmes is investigated.
Abstract: Background
Enhanced recovery programmes (ERPs) have been developed over the past 10 years to improve patient outcomes and to accelerate recovery after surgery. The existing literature focuses on specific specialties, mainly colorectal surgery. The aim of this review was to investigate whether the effect of ERPs on patient outcomes varies across surgical specialties or with the design of individual programmes.
Methods
MEDLINE, Embase, CINAHL and the Cochrane Central Register of Controlled Trials were searched from inception to January 2013 for randomized or quasi-randomized trials comparing ERPs with standard care in adult elective surgical patients.
Results
Thirty-eight trials were included in the review, with a total of 5099 participants. Study design and quality was poor. Meta-analyses showed that ERPs reduced the primary length of stay (standardized mean difference −1·14 (95 per cent confidence interval −1·45 to −0·85)) and reduced the risk of all complications within 30 days (risk ratio (RR) 0·71, 95 per cent c.i. 0·60 to 0·86). There was no evidence of a reduction in mortality (RR 0·69, 95 per cent c.i. 0·34 to 1·39), major complications (RR 0·95, 0·69 to 1·31) or readmission rates (RR 0·96, 0·59 to 1·58). The impact of ERPs was similar across specialties and there was no consistent evidence that elements included within ERPs affected patient outcomes.
Conclusion
ERPs are effective in reducing length of hospital stay and overall complication rates across surgical specialties. It was not possible to identify individual components that improved outcome. Qualitative synthesis may be more appropriate to investigate the determinants of success.
University of Minnesota1, Utah State University2, Iowa State University3, University of Oldenburg4, University of Guelph5, Lancaster University6, University of Washington7, University of Queensland8, Lanzhou University9, University of New Mexico10, Spanish National Research Council11, University of Wisconsin-Madison12, University of Colorado Boulder13, United States Department of Agriculture14, Queensland University of Technology15, University of Maryland, College Park16, Colorado State University17, University of Nebraska–Lincoln18, University of California, Berkeley19, Southwest Forestry University20, University of Kentucky21, University of Melbourne22, Oregon State University23, Commonwealth Scientific and Industrial Research Organisation24, Swiss Federal Institute for Forest, Snow and Landscape Research25, National Centre for Biological Sciences26, University of Oxford27
TL;DR: This paper analyzed diversity-stability relationships from 41 grasslands on five continents and examined how these relationships are affected by chronic fertilization, one of the strongest drivers of species loss globally.
Abstract: Studies of experimental grassland communities have demonstrated that plant diversity can stabilize productivity through species asynchrony, in which decreases in the biomass of some species are compensated for by increases in others. However, it remains unknown whether these findings are relevant to natural ecosystems, especially those for which species diversity is threatened by anthropogenic global change. Here we analyse diversity-stability relationships from 41 grasslands on five continents and examine how these relationships are affected by chronic fertilization, one of the strongest drivers of species loss globally. Unmanipulated communities with more species had greater species asynchrony, resulting in more stable biomass production, generalizing a result from biodiversity experiments to real-world grasslands. However, fertilization weakened the positive effect of diversity on stability. Contrary to expectations, this was not due to species loss after eutrophication but rather to an increase in the temporal variation of productivity in combination with a decrease in species asynchrony in diverse communities. Our results demonstrate separate and synergistic effects of diversity and eutrophication on stability, emphasizing the need to understand how drivers of global change interactively affect the reliable provisioning of ecosystem services in real-world systems.
TL;DR: In this paper, the ATLAS detector at the Large Hadron Collider is used to search for high-mass resonances decaying to dielectron or dimuon final states.
Abstract: The ATLAS detector at the Large Hadron Collider is used to search for high-mass resonances decaying to dielectron or dimuon final states. Results are presented from an analysis of proton-proton (pp) collisions at a center-of-mass energy of 8 TeV corresponding to an integrated luminosity of 20.3 fb(-1) in the dimuon channel. A narrow resonance with Standard Model Z couplings to fermions is excluded at 95% confidence level for masses less than 2.79 TeV in the dielectron channel, 2.53 TeV in the dimuon channel, and 2.90 TeV in the two channels combined. Limits on other model interpretations are also presented, including a grand-unification model based on the E-6 gauge group, Z* bosons, minimal Z' models, a spin-2 graviton excitation from Randall-Sundrum models, quantum black holes, and a minimal walking technicolor model with a composite Higgs boson.
TL;DR: In this paper, the authors demonstrate the importance of studying insecurity in relation to identities at work by drawing upon empirical research with business school academics in the context of the proliferation of managerialist controls of audit, accountability, monitoring and performativity, illustrating how insecurities in the form of fragile and insecure academic selves are variously manifested.
Abstract: This article demonstrates the importance of studying insecurity in relation to identities at work. Drawing upon empirical research with business school academics in the context of the proliferation of managerialist controls of audit, accountability, monitoring and performativity, we illustrate how insecurities in the form of fragile and insecure academic selves are variously manifested. Emerging from our data were three forms of insecurity—imposters, aspirants and those preoccupied with existential concerns, and we analyse these in the context of psychoanalytic, sociological and philosophical frameworks. In so doing, we make a three-fold contribution to the organization studies literature: first, we develop an understanding of identities whereby they are treated as a topic and not merely a resource for studying something else; second, we demonstrate how insecurity and identity are more nuanced and less monolithic concepts than has sometimes been deployed in the literature; and third, we theorize the conce...
TL;DR: In this article, the authors presented the electron and photon energy calibration achieved with the ATLAS detector using about 25 fb(-1) of LHC proton-proton collision data taken at center-of-mass energies of root s = 7 and 8 TeV.
Abstract: This paper presents the electron and photon energy calibration achieved with the ATLAS detector using about 25 fb(-1) of LHC proton-proton collision data taken at centre-of-mass energies of root s = 7 and 8 TeV. The reconstruction of electron and photon energies is optimised using multivariate algorithms. The response of the calorimeter layers is equalised in data and simulation, and the longitudinal profile of the electromagnetic showers is exploited to estimate the passive material in front of the calorimeter and reoptimise the detector simulation. After all corrections, the Z resonance is used to set the absolute energy scale. For electrons from Z decays, the achieved calibration is typically accurate to 0.05% in most of the detector acceptance, rising to 0.2% in regions with large amounts of passive material. The remaining inaccuracy is less than 0.2-1% for electrons with a transverse energy of 10 GeV, and is on average 0.3% for photons. The detector resolution is determined with a relative inaccuracy of less than 10% for electrons and photons up to 60 GeV transverse energy, rising to 40% for transverse energies above 500 GeV.
TL;DR: It is suggested that although MDE might be more widespread than commonly believed, developers rarely use it to generate whole systems.
Abstract: Despite lively debate over the past decade on the benefits and drawbacks of model-driven engineering (MDE), there have been few industry-wide studies of MDE in practice. A new study that surveyed 450 MDE practitioners and performed in-depth interviews with 22 more suggests that although MDE might be more widespread than commonly believed, developers rarely use it to generate whole systems. Rather, they apply MDE to develop key parts of a system.
TL;DR: In this paper, a measurement of the Z/gamma* boson transverse momentum spectrum using ATLAS proton-proton collision data at a centre-of-mass energy of root s = 7TeV at the LHC is described.
Abstract: This paper describes a measurement of the Z/gamma* boson transverse momentum spectrum using ATLAS proton-proton collision data at a centre-of-mass energy of root s = 7TeV at the LHC. The measurement is performed in the Z/gamma* -> e(+)e(-) and Z/gamma* -> mu(+)mu(-) channels, using data corresponding to an integrated luminosity of 4.7 fb(-1). Normalized differential cross sections as a function of the Z/gamma* boson transverse momentum are measured for transverse momenta up to 800 GeV. The measurement is performed inclusively for Z/gamma* rapidities up to 2.4, as well as in three rapidity bins. The channel results are combined, compared to perturbative and resummed QCD calculations and used to constrain the parton shower parameters of Monte Carlo generators.
TL;DR: In this article, a search for squarks and gluinos in final states containing high-p T jets, missing transverse momentum and no electrons or muons is presented.
Abstract: A search for squarks and gluinos in final states containing high-p T jets, missing transverse momentum and no electrons or muons is presented. The data were recorded in 2012 by the ATLAS experiment in s√=8 TeV proton-proton collisions at the Large Hadron Collider, with a total integrated luminosity of 20.3 fb−1. Results are interpreted in a variety of simplified and specific supersymmetry-breaking models assuming that R-parity is conserved and that the lightest neutralino is the lightest supersymmetric particle. An exclusion limit at the 95% confidence level on the mass of the gluino is set at 1330 GeV for a simplified model incorporating only a gluino and the lightest neutralino. For a simplified model involving the strong production of first- and second-generation squarks, squark masses below 850 GeV (440 GeV) are excluded for a massless lightest neutralino, assuming mass degenerate (single light-flavour) squarks. In mSUGRA/CMSSM models with tan β = 30, A 0 = −2m 0 and μ > 0, squarks and gluinos of equal mass are excluded for masses below 1700 GeV. Additional limits are set for non-universal Higgs mass models with gaugino mediation and for simplified models involving the pair production of gluinos, each decaying to a top squark and a top quark, with the top squark decaying to a charm quark and a neutralino. These limits extend the region of supersymmetric parameter space excluded by previous searches with the ATLAS detector.
TL;DR: A short-term effect on pain is found of active high-frequency stimulation of the motor cortex in single-dose studies of repetitive transcranial magnetic stimulation and this equates to a 12% reduction in pain, which does not exceed the pre-established criteria for a minimal clinically important difference.
Abstract: Copyright © 2011 The Cochrane Collaboration. This review is published as a Cochrane Review in the Cochrane Database of Systematic Reviews 2010, Issue 9. Cochrane Reviews are regularly updated as new evidence emerges and in response to comments and criticisms, and the Cochrane Database of Systematic Reviews should be consulted for the most recent version of the Review.
TL;DR: Both the high photoresponsivity and the fast response time described in the present study strongly suggest that multilayer GaTe is a promising candidate for future optoelectronic and photosensitive device applications.
Abstract: Optoelectronic devices based on layered materials such as graphene have resulted in significant interest due to their unique properties and potential technological applications. The electric and optoelectronic properties of nano GaTe flakes as layered materials are described in this article. The transistor fabricated from multilayer GaTe shows a p-type action with a hole mobility of about 0.2 cm2 V–1 s–1. The gate transistor exhibits a high photoresponsivity of 104 A/W, which is greatly better than that of graphene, MoS2, and other layered compounds. Meanwhile, the response speed of 6 ms is also very fast. Both the high photoresponsivity and the fast response time described in the present study strongly suggest that multilayer GaTe is a promising candidate for future optoelectronic and photosensitive device applications.
TL;DR: Carbon loss and subsequent emissions due to human disturbances remain largely unaccounted for in greenhouse gas inventories, but by comparing estimates of depleted carbon stocks in disturbed forests with Brazilian government assessments of the total forest area annually disturbed in the Amazon, it is shown that these emissions could represent up to 40% of the carbon loss from deforestation in the region.
Abstract: Tropical rainforests store enormous amounts of carbon, the protection of which represents a vital component of efforts to mitigate global climate change. Currently, tropical forest conservation, science, policies, and climate mitigation actions focus predominantly on reducing carbon emissions from deforestation alone. However, every year vast areas of the humid tropics are disturbed by selective logging, understory fires, and habitat fragmentation. There is an urgent need to understand the effect of such disturbances on carbon stocks, and how stocks in disturbed forests compare to those found in undisturbed primary forests as well as in regenerating secondary forests. Here, we present the results of the largest field study to date on the impacts of human disturbances on above and belowground carbon stocks in tropical forests. Live vegetation, the largest carbon pool, was extremely sensitive to disturbance: forests that experienced both selective logging and understory fires stored, on average, 40% less aboveground carbon than undisturbed forests and were structurally similar to secondary forests. Edge effects also played an important role in explaining variability in aboveground carbon stocks of disturbed forests. Results indicate a potential rapid recovery of the dead wood and litter carbon pools, while soil stocks (0–30 cm) appeared to be resistant to the effects of logging and fire. Carbon loss and subsequent emissions due to human disturbances remain largely unaccounted for in greenhouse gas inventories, but by comparing our estimates of depleted carbon stocks in disturbed forests with Brazilian government assessments of the total forest area annually disturbed in the Amazon, we show that these emissions could represent up to 40% of the carbon loss from deforestation in the region. We conclude that conservation programs aiming to ensure the long-term permanence of forest carbon stocks, such as REDD+, will remain limited in their success unless they effectively avoid degradation as well as deforestation.
TL;DR: In this paper, the sufficiency condition for family involvement to produce family-oriented particularistic behavior in a firm requires the presence of both ability and willingness, and they demonstrate how the omission of this sufficient condition in commonly used theoretical models employed to explain how family involvement affects firm behavior can result in theoretical limitations and empirical indeterminacy.
Abstract: Distinguishing sufficient conditions from necessary conditions is crucial in both theoretical and empirical studies. We propose that the sufficiency condition for family involvement to produce family-oriented particularistic behavior in a firm requires the presence of both ability and willingness. We demonstrate how the omission of this sufficiency condition in commonly used theoretical models employed to explain how family involvement affects firm behavior can result in theoretical limitations and empirical indeterminacy. Finally, we discuss how considering both ability and willingness can lead to better theory, more generalizable empirical findings, and help explain heterogeneity among firms with family involvement.