Southern Illinois University Carbondale

About: Southern Illinois University Carbondale is a education organization based out in Carbondale, Illinois, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 13570 authors who have published 24819 publications receiving 667385 citations. The organization is also known as: SIU Carbondale & SIUC.

Variations in Social Support Associated with Gender, Ethnicity, and Age

Abstract: Much of the research conducted on social support over the last decade has focused on specific population groups. Until recently, very little work compared social support across groups. The importance of this type of research is discussed, including the potential role of social support in explaining subpopulation differences in psychological distress. Studies are reviewed that compare support and support effects across sex, ethnic, and age groups. In general, the findings suggest that levels of some aspects of support and the effectiveness of support components vary across these subgroups. Even the stress-buffering versus direct-effect functions of social support may vary across subgroups, as illustrated by one study focusing on social class. The implications of these studies and directions for future research are discussed.

The cutaneous serotoninergic/melatoninergic system: securing a place under the sun

Abstract: It was recently discovered that mammalian skin can produce serotonin and transform it into melatonin. Pathways for the biosynthesis and biodegradation of serotonin and melatonin have been characterized in human and rodent skin and in their major cellular populations. Moreover, receptors for serotonin and melatonin receptors are expressed in keratinocytes, melanocytes, and fibroblasts and these mediate phenotypic actions on cellular proliferation and differentiation. Melatonin exerts receptor-independent effects, including activation of pathways protective of oxidative stress and the modification of cellular metabolism. While serotonin is known to have several roles in skin-e.g., pro-edema, vasodilatory, proinflammatory, and pruritogenic-melatonin has been experimentally implicated in hair growth cycling, pigmentation physiology, and melanoma control. Thus, the widespread expression of a cutaneous seorotoninergic/melatoninergic syste,m(s) indicates considerable selectivity of action to facilitate intra-, auto-, or paracrine mechanisms that define and influence skin function in a highly compartmentalized manner. Notably, the cutaneous melatoninergic system is organized to respond to continuous stimulation in contrast to the pineal gland, which (being insulated from the external environment) responds to discontinuous activation by the circadian clock. Overall, the cutaneous serotoninergic/melatoninergic system could counteract or buffer external (environmental) or internal stresses to preserve the biological integrity of the organ and to maintain its homeostasis.-Slominski, A. J., Wortsman, J., Tobin, D. J. The cutaneous serotoninergic/melatoninergic system: securing a place under the sun.

Boards of directors, ownership, and regulation

Abstract: In this paper we examine whether regulation can be used to substitute for internal monitoring mechanisms (percentage of outside directors, officer and director common stock ownership, and CEO/Chair duality) to control for agency conflicts in a firm. We find that, in general, the percentage of outside directors is negatively related to insider stock ownership, but is not affected by CEO/Chair duality. CEO/Chair duality is, however, less likely when insider stock ownership increases. We find these internal monitoring mechanisms to be significantly less related with regulated firms (banks and utilities). We conclude that to the extent that regulations reduce the impact of managerial decisions on shareholder wealth, effective internal monitoring of managers becomes less important in controlling agency conflicts. 2002 Elsevier Science B.V. All rights reserved.