Showing papers by "University of Maryland, Baltimore County published in 2005"

A survey on routing protocols for wireless sensor networks

Abstract: Recent advances in wireless sensor networks have led to many new protocols specifically designed for sensor networks where energy awareness is an essential consideration. Most of the attention, however, has been given to the routing protocols since they might differ depending on the application and network architecture. This paper surveys recent routing protocols for sensor networks and presents a classification for the various approaches pursued. The three main categories explored in this paper are data-centric, hierarchical and location-based. Each routing protocol is described and discussed under the appropriate category. Moreover, protocols using contemporary methodologies such as network flow and quality of service modeling are also discussed. The paper concludes with open research issues. � 2003 Elsevier B.V. All rights reserved.

Genome analysis of multiple pathogenic isolates of Streptococcus agalactiae: Implications for the microbial “pan-genome”

Abstract: The development of efficient and inexpensive genome sequencing methods has revolutionized the study of human bacterial pathogens and improved vaccine design. Unfortunately, the sequence of a single genome does not reflect how genetic variability drives pathogenesis within a bacterial species and also limits genome-wide screens for vaccine candidates or for antimicrobial targets. We have generated the genomic sequence of six strains representing the five major disease-causing serotypes of Streptococcus agalactiae, the main cause of neonatal infection in humans. Analysis of these genomes and those available in databases showed that the S. agalactiae species can be described by a pan-genome consisting of a core genome shared by all isolates, accounting for ≈80% of any single genome, plus a dispensable genome consisting of partially shared and strain-specific genes. Mathematical extrapolation of the data suggests that the gene reservoir available for inclusion in the S. agalactiae pan-genome is vast and that unique genes will continue to be identified even after sequencing hundreds of genomes.

Loss of foundation species: consequences for the structure and dynamics of forested ecosystems

Abstract: In many forested ecosystems, the architecture and functional ecology of certain tree species define forest structure and their species-specific traits control ecosystem dynamics. Such foundation tree species are declining throughout the world due to introductions and outbreaks of pests and pathogens, selective removal of individual taxa, and over-harvesting. Through a series of case studies, we show that the loss of foundation tree species changes the local environment on which a variety of other species depend; how this disrupts fundamental ecosystem processes, including rates of decomposition, nutrient fluxes, carbon sequestration, and energy flow; and dramatically alters the dynamics of associated aquatic ecosystems. Forests in which dynamics are controlled by one or a few foundation species appear to be dominated by a small number of strong interactions and may be highly susceptible to alternating between stable states following even small perturbations. The ongoing decline of many foundation species provides a set of important, albeit unfortunate, opportunities to develop the research tools, models, and metrics needed to identify foundation species, anticipate the cascade of immediate, short- and long-term changes in ecosystem structure and function that will follow from their loss, and provide options for remedial conservation and management.

Analysis and quantification of the diversities of aerosol life cycles within AeroCom

Abstract: Simulation results of global aerosol models have been assembled in the framework of the AeroCom intercomparison exercise. In this paper, we analyze the life cycles of dust, sea salt, sulfate, black carbon and particulate organic matter as simulated by sixteen global aerosol models. The differences among the results (model diversities) for sources and sinks, burdens, particle sizes, water uptakes, and spatial dispersals have been established. These diversities have large consequences for the calculated radiative forcing and the aerosol concentrations at the surface. Processes and parameters are identified which deserve further research. The AeroCom all-models-average emissions are dominated by the mass of sea salt (SS), followed by dust (DU), sulfate (SO 4 ), particulate organic matter (POM), and finally black carbon (BC). Interactive parameterizations of the emissions and contrasting particles sizes of SS and DU lead generally to higher diversities of these species, and for total aerosol. The lower diversity of the emissions of the fine aerosols, BC, POM, and SO 4 , is due to the use of similar emission inventories, and does therefore not necessarily indicate a better understanding of their sources. The diversity of SO 4 -sources is mainly caused by the disagreement on depositional loss of precursor gases and on chemical production. The diversities of the emissions are passed on to the burdens, but the latter are also strongly affected by the model-specific treatments of transport and aerosol processes. The burdens of dry masses decrease from largest to smallest: DU, SS, SO 4 , POM, and BC. The all-models-average residence time is shortest for SS with about half a day, followed by SO 4 and DU with four days, and POM and BC with six and seven days, respectively. The wet deposition rate is controlled by the solubility and increases from DU, BC, POM to SO 4 and SS. It is the dominant sink for SO 4 , BC, and POM, and contributes about one third to the total removal of SS and DU species. For SS and DU we find high diversities for the removal rate coefficients and deposition pathways. Models do neither agree on the split between wet and dry deposition, nor on that between sedimentation and other dry deposition processes. We diagnose an extremely high diversity for the uptake of ambient water vapor that influences the particle size and thus the sink rate coefficients. Furthermore, we find little agreement among the model results for the partitioning of wet removal into scavenging by convective and stratiform rain. Large differences exist for aerosol dispersal both in the vertical and in the horizontal direction. In some models, a minimum of total aerosol concentration is simulated at the surface. Aerosol dispersal is most pronounced for SO 4 and BC and lowest for SS. Diversities are higher for meridional than for vertical dispersal, they are similar for the individual species and highest for SS and DU. For these two components we do not find a correlation between vertical and meridional aerosol dispersal. In addition the degree of dispersals of SS and DU is not related to their residence times. SO 4 , BC, and POM, however, show increased meridional dispersal in models with larger vertical dispersal, and dispersal is larger for longer simulated residence times.

Recent trends in vegetation dynamics in the African Sahel and their relationship to climate

Abstract: Contrary to assertions of widespread irreversible desertification in the African Sahel, a recent increase in seasonal greenness over large areas of the Sahel has been observed, which has been interpreted as a recovery from the great Sahelian droughts. This research investigates temporal and spatial patterns of vegetation greenness and rainfall variability in the African Sahel and their interrelationships based on analyses of Normalized Difference Vegetation Index (NDVI) time series for the period 1982–2003 and gridded satellite rainfall estimates. While rainfall emerges as the dominant causative factor for the increase in vegetation greenness, there is evidence of another causative factor, hypothetically a human-induced change superimposed on the climate trend. r 2005 Elsevier Ltd. All rights reserved.

Increased salinization of fresh water in the northeastern United States

Abstract: Chloride concentrations are increasing at a rate that threatens the availability of fresh water in the northeastern United States. Increases in roadways and deicer use are now salinizing fresh waters, degrading habitat for aquatic organisms, and impacting large supplies of drinking water for humans throughout the region. We observed chloride concentrations of up to 25% of the concentration of seawater in streams of Maryland, New York, and New Hampshire during winters, and chloride concentrations remaining up to 100 times greater than unimpacted forest streams during summers. Mean annual chloride concentration increased as a function of impervious surface and exceeded tolerance for freshwater life in suburban and urban watersheds. Our analysis shows that if salinity were to continue to increase at its present rate due to changes in impervious surface coverage and current management practices, many surface waters in the northeastern United States would not be potable for human consumption and would become toxic to freshwater life within the next century.

A review of measurement-based assessments of the aerosol direct radiative effect and forcing

Abstract: Aerosols affect the Earth's energy budget directly by scattering and absorbing radiation and indirectly by acting as cloud condensation nuclei and, thereby, affecting cloud properties. However, large uncertainties exist in current estimates of aerosol forcing because of incomplete knowledge concerning the distribution and the physical and chemical properties of aerosols as well as aerosol-cloud interactions. In recent years, a great deal of effort has gone into improving measurements and datasets. It is thus feasible to shift the estimates of aerosol forcing from largely model-based to increasingly measurement-based. Our goal is to assess current observational capabilities and identify uncertainties in the aerosol direct forcing through comparisons of different methods with independent sources of uncertainties. Here we assess the aerosol optical depth (τ), direct radiative effect (DRE) by natural and anthropogenic aerosols, and direct climate forcing (DCF) by anthropogenic aerosols, focusing on satellite and ground-based measurements supplemented by global chemical transport model (CTM) simulations. The multi-spectral MODIS measures global distributions of aerosol optical depth (τ) on a daily scale, with a high accuracy of ±0.03±0.05τ over ocean. The annual average τ is about 0.14 over global ocean, of which about 21%±7% is contributed by human activities, as estimated by MODIS fine-mode fraction. The multi-angle MISR derives an annual average AOD of 0.23 over global land with an uncertainty of ~20% or ±0.05. These high-accuracy aerosol products and broadband flux measurements from CERES make it feasible to obtain observational constraints for the aerosol direct effect, especially over global the ocean. A number of measurement-based approaches estimate the clear-sky DRE (on solar radiation) at the top-of-atmosphere (TOA) to be about -5.5±0.2 Wm -2 (median ± standard error from various methods) over the global ocean. Accounting for thin cirrus contamination of the satellite derived aerosol field will reduce the TOA DRE to -5.0 Wm -2 . Because of a lack of measurements of aerosol absorption and difficulty in characterizing land surface reflection, estimates of DRE over land and at the ocean surface are currently realized through a combination of satellite retrievals, surface measurements, and model simulations, and are less constrained. Over the oceans the surface DRE is estimated to be -8.8±0.7 Wm -2 . Over land, an integration of satellite retrievals and model simulations derives a DRE of -4.9±0.7 Wm -2 and -11.8±1.9 Wm -2 at the TOA and surface, respectively. CTM simulations derive a wide range of DRE estimates that on average are smaller than the measurement-based DRE by about 30-40%, even after accounting for thin cirrus and cloud contamination. A number of issues remain. Current estimates of the aerosol direct effect over land are poorly constrained. Uncertainties of DRE estimates are also larger on regional scales than on a global scale and large discrepancies exist between different approaches. The characterization of aerosol absorption and vertical distribution remains challenging. The aerosol direct effect in the thermal infrared range and in cloudy conditions remains relatively unexplored and quite uncertain, because of a lack of global systematic aerosol vertical profile measurements. A coordinated research strategy needs to be developed for integration and assimilation of satellite measurements into models to constrain model simulations. Enhanced measurement capabilities in the next few years and high-level scientific cooperation will further advance our knowledge.

An AeroCom Initial Assessment - Optical Properties in Aerosol Component Modules of Global Models

Abstract: The AeroCom exercise diagnoses multi-component aerosol modules in global modeling. In an initial assessment simulated global distributions for mass and mid-visible aerosol optical thickness (aot) were compared among 20 different modules. Model diversity was also explored in the context of previous comparisons. For the component combined aot general agreement has improved for the annual global mean. At 0.11 to 0.14, simulated aot values are at the lower end of global averages suggested by remote sensing from ground (AERONET ca. 0.135) and space (satellite composite ca. 0.15). More detailed comparisons, however, reveal that larger differences in regional distribution and significant differences in compositional mixture remain. Of particular concern are large model diversities for contributions by dust and carbonaceous aerosol, because they lead to significant uncertainty in aerosol absorption (aab). Since aot and aab, both, influence the aerosol impact on the radiative energy-balance, the aerosol (direct) forcing uncertainty in modeling is larger than differences in aot might suggest. New diagnostic approaches are proposed to trace model differences in terms of aerosol processing and transport: These include the prescription of common input (e.g. amount, size and injection of aerosol component emissions) and the use of observational capabilities from ground (e.g. measurements networks) or space (e.g. correlations between aerosol and clouds).

Advancing E-Government at the Grassroots: Tortoise or Hare?

Abstract: American grassroots governments have rushed to join the e-government revolution. Although there is a growing body of e-government literature, little of it is empirical. Using data from two nationwide surveys, we conduct a longitudinal examination of local government adoption of e-government, Web site sophistication, the perceived impacts of e-government, and barriers to the adoption and sophistication of e-government. We also discuss correlates of e-government adoption and sophistication with selected institutional factors. We find that e-government adoption at the grassroots is progressing rapidly (if measured solely by deployment of Web sites). However, the movement toward integrated and transactional e-government is progressing much more slowly. Continuing research, particularly longitudinal study, is needed to monitor the evolution of e-government among U.S. local governments, especially to keep pace with the practice and to ascertain the actual impacts of e-government.

Two-photon imaging with thermal light.

Abstract: We report the first experimental demonstration of two-photon imaging with a pseudothermal source. Similarly to the case of entangled states, a two-photon Gaussian thin lens equation is observed, indicating EPR type correlation in position. We introduce the concepts of two-photon coherent and two-photon incoherent imaging. The differences between the entangled and the thermal cases are explained in terms of these concepts.

A short γ-ray burst apparently associated with an elliptical galaxy at redshift z = 0.225

Abstract: Gamma-ray bursts (GRBs) are either ‘long and soft’, or ‘short and hard’. The long-duration type leave a strong afterglow and have been extensively studied. So we have a good idea of what causes them: explosions of massive stars in distant star-forming galaxies. Short GRBs, with no strong afterglow, were harder to pin down. The Swift satellite, launched last November, is designed to study bursts as soon as they happen. Having shown its worth with long GRBs (reported in the 18 August issue of Nature), Swift has now bagged a short burst, GRB 050509B, precisely measured its location and detected the X-ray afterglow. Four papers this week report on this and another recent short burst. Now, over 20 years after they were first recognized, the likely origin of the short GRBs is revealed as a merger between neutron stars of a binary system and the instantaneous production of a black hole. Gamma-ray bursts (GRBs) come in two classes1: long (> 2 s), soft-spectrum bursts and short, hard events. Most progress has been made on understanding the long GRBs, which are typically observed at high redshift (z ≈ 1) and found in subluminous star-forming host galaxies. They are likely to be produced in core-collapse explosions of massive stars2. In contrast, no short GRB had been accurately (< 10″) and rapidly (minutes) located. Here we report the detection of the X-ray afterglow from—and the localization of—the short burst GRB 050509B. Its position on the sky is near a luminous, non-star-forming elliptical galaxy at a redshift of 0.225, which is the location one would expect3,4 if the origin of this GRB is through the merger of neutron-star or black-hole binaries. The X-ray afterglow was weak and faded below the detection limit within a few hours; no optical afterglow was detected to stringent limits, explaining the past difficulty in localizing short GRBs.

Aerosol invigoration and restructuring of Atlantic convective clouds

Abstract: [1] Clouds and precipitation play crucial roles in the Earth's energy balance, global atmospheric circulation and the availability of fresh water. Aerosols may modify cloud properties and precipitation formation by modifying the concentration and size of cloud droplets, and consequently the strength of cloud convection, and height of glaciation levels thus affecting precipitation patterns. Here we evaluate the aerosol effect on clouds, using large statistics of daily satellite data over the North Atlantic Ocean. We found a strong correlation between the presence of aerosols and the structural properties of convective clouds. These correlations suggest systematic invigoration of convective clouds by pollution, desert dust and biomass burning aerosols. On average increase in the aerosol concentration from a baseline to the average values is associated with a 0.05 ± 0.01 increase in the cloud fraction and a 40 ± 5mb decrease in the cloud top pressure.

Reduction of Myeloid-Derived Suppressor Cells and Induction of M1 Macrophages Facilitate the Rejection of Established Metastatic Disease

Abstract: More than 60% of STAT6(-/-) mice immunologically reject spontaneous metastatic mammary carcinoma and survive indefinitely if their primary tumors are removed, whereas 95% of STAT6-competent BALB/c mice succumb to metastatic disease. BALB/c and STAT6-deficient mice with primary tumors have elevated levels of Gr1(+)CD11b(+) myeloid suppressor cells (MSCs), which inhibit T cell activation. After removal of primary tumor, MSC levels revert to baseline in STAT6-deficient mice, but remain elevated in BALB/c mice. The decrease is IFN-gamma dependent, as is the reduction in metastatic disease. Neither BALB/c nor STAT6-deficient MSCs produce inducible NO synthase; however, both produce arginase and reactive oxygen species. STAT6-deficient mice produce M1 macrophages, which contain high levels of NO and are tumoricidal, whereas BALB/c mice produce M2 macrophages, which make arginase and are not tumoricidal. Immunity in STAT6-deficient mice requires the activation of NO-producing M1 macrophages that are tumoricidal, the reduction in MSC levels to baseline after surgical removal of primary tumor, and the activation of tumor-specific T cells. These mechanisms occur in STAT6(-/-) mice because STAT6 deficiency prevents signaling through the type 2 IL-4Ralpha, thereby blocking the production of arginase and promoting the synthesis of NO.

Does managerial orientation matter? The adoption of reinventing government and e-government at the municipal level*

Abstract: . This paper explores the effect of managerial innovativeness in municipal government on the adoption of e-government, and it examines the association between the adoption of e-government and its outcome. The authors posit an exploratory model: The first part of the model shows how adoption of municipal e-government is determined by managerial innovativeness orientation, government capacity and institutional characteristics such as city size and government type. The second part suggests how e-government outcomes are associated with the adoption of e-government, government capacity and institutional characteristics. Analysing two different survey data sets of American municipal reinvention and e-government, this study finds that managerial innovativeness orientation and city size are the most compelling determinants of municipal e-government adoption. Different levels of e-government adoption may yield different outcomes.

Columnar aerosol optical properties at AERONET sites in central eastern Asia and aerosol transport to the tropical mid‐Pacific

Abstract: [1] The column-integrated optical properties of aerosol in the central eastern region of Asia and midtropical Pacific were investigated based on Sun/sky radiometer measurements made at Aerosol Robotic Network (AERONET) sites in these regions. Characterization of aerosol properties in the Asian region is important due to the rapid growth of both population and economic activity, with associated increases in fossil fuel combustion, and the possible regional and global climatic impacts of related aerosol emissions. Multiyear monitoring over the complete annual cycle at sites in China, Mongolia, South Korea, and Japan suggest spring and/or summer maximum in aerosol optical depth (τa) and a winter minimum; however, more monitoring is needed to establish accurate climatologies. The annual cycle of Angstrom wavelength exponent (α) showed a springtime minimum associated with dust storm activity; however, the monthly mean α440–870 was >0.8 even for the peak dust season at eastern Asian sites suggesting that fine mode pollution aerosol emitted from population centers in eastern Asia dominates the monthly aerosol optical influence even in spring as pollution aerosol mixes with coarse mode dust originating in western source regions. Aerosol optical depth peaks in spring in the tropical mid-Pacific Ocean associated with seasonal shifts in atmospheric transport from Asia, and ∼35% of the springtime τa500 enhancement occurs at altitudes above 3.4 km. For predominately fine mode aerosol pollution cases, the average midvisible (∼550 nm) single scattering albedo (ω0) at two continental urban sites in China averaged ∼0.89, while it was significantly higher, ∼0.93, at two relatively rural coastal sites in South Korea and Japan. Differences in fine mode absorption between these regions may result from a combination of factors including aerosol aging during transport, relative humidity differences, sea salt at coastal sites, and fuel type and combustion differences in the two regions. For cases where τa was predominately coarse mode dust aerosol in the spring of 2001, the absorption was greater in eastern Asia compared to the source regions, with ω0 at Dunhuang, China (near to the major Taklamakan dust source), ∼0.04 higher than at Beijing at all wavelengths, and Anmyon, South Korea, showing an intermediate level of absorption. Possible reasons for differences in dust absorption magnitude include interactions between dust and fine mode pollution aerosol and also variability of dust optical properties from different source regions in China and Mongolia.

Movie Review Mining: a Comparison between Supervised and Unsupervised Classification Approaches

Abstract: Web content mining is intended to help people discover valuable information from large amount of unstructured data on the web. Movie review mining classifies movie reviews into two polarities: positive and negative. As a type of sentiment-based classification, movie review mining is different from other topic-based classifications. Few empirical studies have been conducted in this domain. This paper investigates movie review mining using two approaches: machine learning and semantic orientation. The approaches are adapted to movie review domain for comparison. The results show that our results are comparable to or even better than previous findings. We also find that movie review mining is a more challenging application than many other types of review mining. The challenges of movie review mining lie in that factual information is always mixed with real-life review data and ironic words are used in writing movie reviews. Future work for improving existing approaches is also suggested.

Social networks applied

Abstract: Social networks have interesting properties. They influence our lives enormously without us being aware of the implications they raise. The authors investigate the following areas concerning social networks: how to exploit our unprecedented wealth of data and how we can mine social networks for purposes such as marketing campaigns; social networks as a particular form of influence, i.e.., the way that people agree on terminology and this phenomenon's implications for the way we build ontologies and the Semantic Web; social networks as something we can discover from data; the use of social network information to offer a wealth of new applications such as better recommendations for restaurants, trustworthy email senders, or (maybe) blind dates; investigation of the richness and difficulty of harvesting FOAF (friend-of-a-friend) information; and by looking at how information processing is bound to social context, the resulting ways that network topology's definition determines its outcomes.

How retroviruses select their genomes

Abstract: As retroviruses assemble in infected cells, two copies of their full-length, unspliced RNA genomes are selected for packaging from a cellular milieu that contains a substantial excess of non-viral and spliced viral RNAs. Understanding the molecular details of genome packaging is important for the development of new antiviral strategies and to enhance the efficacy of retroviral vectors used in human gene therapy. Recent studies of viral RNA structure in vitro and in vivo and high-resolution studies of RNA fragments and protein–RNA complexes are helping to unravel the mechanism of genome packaging and providing the first glimpses of the initial stages of retrovirus assembly.

Development of global aerosol models using cluster analysis of Aerosol Robotic Network (AERONET) measurements

Abstract: [1] We use radiance measurements and inversions of the Aerosol Robotic Network (AERONET) (Dubovik and King, 2000; Holben et al., 1998; Holben et al., 2001) to classify global atmospheric aerosols using the complete archive of the AERONET data set as of December 2002 and dating back to 1993 for some sites. More than 143,000 records of AERONET solar radiance measurements, derived aerosol size distributions, and complex refractive indices are used to generate the optical properties of the aerosol at more than 250 sites worldwide. Each record is used in a clustering algorithm as an object, with 26 variables comprising both microphysical and optical properties to obtain six significant clusters. Using the mean values of the optical and microphysical properties together with the geographic locations, we identified these clusters as desert dust, biomass burning, urban industrial pollution, rural background, polluted marine, and dirty pollution. When the records in each cluster are subdivided by optical depth class, the trends of the class size distributions show that the extensive properties (mode amplitude and total volume) vary by optical depth, while the intensive properties (mean radius and standard deviation) are relatively constant. Seasonal variations of aerosol types are consistent with observed trends. In particular, the periods of intense biomass burning activity and desert dust generation can be discerned from the data and the results of the analyses. Sensitivity and uncertainty analyses show that the clustering algorithm is quite robust. When subsets of the data set are randomly created and the clustering algorithm applied, we found that more than 94% of the records retain their classification. Adding 10% random noise to the microphysical properties and propagating this error through the scattering calculations, followed by the clustering algorithm, results in a misclassification rate of less than 9% when compared with the noise-free data.

Interleukin-13-regulated M2 macrophages in combination with myeloid suppressor cells block immune surveillance against metastasis.

Abstract: CD1-deficient mice reject established, disseminated 4T1 metastatic mammary cancer and survive indefinitely if their primary mammary tumors are surgically removed. This highly effective immune surveillance is due to three interacting mechanisms: (a) the generation of inducible nitric oxide synthase (iNOS)-producing M1 macrophages that are tumoricidal for 4T1 tumor cells; (b) a rapid decrease in myeloid-derived Gr1(+)CD11b(+) suppressor cells that are elevated and down-regulate the CD3zeta chain when primary tumor is present and that suppress T cells by producing arginase; and (c) production of activated lymphocytes. Macrophages from wild-type BALB/c mice are polarized by interleukin-13 (IL-13) towards a tumor-promoting M2 phenotype, thereby inhibiting the generation of tumoricidal M1 macrophages. In contrast, CD1(-/-) mice, which are deficient for IL-13 because they lack IL-13-producting NKT cells, generate M1 macrophages that are cytotoxic for 4T1 via the production of nitric oxide. Although tumoricidal macrophages are a necessary component of immune surveillance in CD1(-/-) mice, they alone are not sufficient for tumor resistance because IL-4Ralpha(-/-) mice have M1 macrophages and retain high levels of myeloid suppressor cells after surgery; in addition, they are susceptible to 4T1 metastatic disease. These results show that effective immune surveillance against established metastatic disease is negatively regulated by IL-13 and requires the induction of tumoricidal M1 macrophages and lymphocytes combined with a reduction in tumor-induced myeloid suppressor cells.

Interpolating implicit surfaces from scattered surface data using compactly supported radial basis functions

Abstract: We describe algebraic methods for creating implicit surfaces using linear combinations of radial basis interpolants to form complex models from scattered surface points. Shapes with arbitrary topology are easily represented without the usual interpolation or aliasing errors arising from discrete sampling. These methods were first applied to implicit surfaces by Savchenko, et al. and later developed independently by Turk and O'Brien as a means of performing shape interpolation. Earlier approaches were limited as a modeling mechanism because of the order of the computational complexity involved. We explore and extend these implicit interpolating methods to make them suitable for systems of large numbers of scattered surface points by using compactly supported radial basis interpolants. The use of compactly supported elements generates a sparse solution space, reducing the computational complexity and making the technique practical for large models. The local nature of compactly supported radial basis functions permits the use of computational techniques and data structures such as k-d trees for spatial subdivision, promoting fast solvers and methods to divide and conquer many of the subproblems associated with these methods. Moreover, the representation of complex models permits the exploration of diverse surface geometry. This reduction in computational complexity enables the application of these methods to the study of shape properties of large complex shapes.

Growing typhoon influence on east Asia

Abstract: Numerical model studies have suggested that the ongoing global warming will likely affect tropical cyclone activity. But so far little observed evidence has been detected to support the projected future changes. Using satellite-supported best-track data from 1965 to 2003, we show for the first time that over the past four decades the two prevailing typhoon tracks in the western North Pacific (WNP) have shifted westward significantly; the typhoon activity over the South China Sea has considerably decreased; and East Asia has experienced increasing typhoon influence. Our trajectory model simulation indicates that the long-term shifts in the typhoon tracks result primarily from the changes in the mean translation velocity of typhoons or the large-scale steering flow, which is associated with the westward expansion and strengthening of the WNP subtropical high.

Long-term follow-up to a randomized clinical trial of multisystemic therapy with serious and violent juvenile offenders.

Abstract: In this study, the authors examined the long-term criminal activity of 176 youths who had participated in either multisystemic therapy (MST) or individual therapy (IT) in a randomized clinical trial (C. M. Borduin et al., 1995). Arrest and incarceration data were obtained on average 13.7 (range = 10.2-15.9) years later when participants were on average 28.8 years old. Results show that MST participants had significantly lower recidivism rates at follow-up than did their counterparts who participated in IT (50% vs. 81%, respectively). Moreover, MST participants had 54% fewer arrests and 57% fewer days of confinement in adult detention facilities. This investigation represents the longest follow-up to date of a MST clinical trial and suggests that MST is relatively effective in reducing criminal activity among serious and violent juvenile offenders.

Online Communities: Design, Theory, and Practice

Abstract: This special thematic section of the Journal of Computer-Mediated Communication brings together nine articles that provide a rich composite of the current research in online communities. The articles cover a range of topics, methodologies, theories and practices. Indirectly they all speak to design since they aim to extend our understanding of the field. The variety shown in these articles illustrates how broad the definition is of this rapidly growing field known as ‘online communities.’

A nonclassical non-Vα14Jα18 CD1d-restricted (type II) NKT cell is sufficient for down-regulation of tumor immunosurveillance

Abstract: The importance of immunoregulatory T cells has become increasingly apparent. Both CD4+CD25+ T cells and CD1d-restricted NKT cells have been reported to down-regulate tumor immunity in mouse tumor models. However, the relative roles of both T cell populations have rarely been clearly distinguished in the same tumor models. In addition, CD1d-restricted NKT cells have been reported to play a critical role not only in the down-regulation of tumor immunity but also in the promotion of the immunity. However, the explanation for these apparently opposite roles in different tumor models remains unclear. We show that in four mouse tumor models in which CD1d-restricted NKT cells play a role in suppression of tumor immunity, depletion of CD4+CD25+ T cells did not induce enhancement of immunosurveillance. Surprisingly, among the two subpopulations of CD1d-restricted NKT cells, Valpha14Jalpha18+ (type I) and Valpha14Jalpha18- (type II) NKT cells, type I NKT cells were not necessary for the immune suppression. These unexpected results may now resolve the paradox in the role of CD1d-restricted NKT cells in the regulation of tumor immunity, in that type II NKT cells may be sufficient for negative regulation, whereas protection has been found to be mediated by alpha-galactosylceramide-responsive type I NKT cells.