Institution
University of Missouri
Education•Columbia, Missouri, United States•
About: University of Missouri is a education organization based out in Columbia, Missouri, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 41427 authors who have published 83598 publications receiving 2911437 citations. The organization is also known as: Mizzou & Missouri-Columbia.
Topics: Population, Poison control, Gene, Context (language use), Health care
Papers published on a yearly basis
Papers
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TL;DR: In this article, the authors present TMT as a way to understand how the human awareness of death affects materialism, conspicuous consumption, and consumer decisions, and the challenges for future research to discover ways to alleviate them.
377 citations
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TL;DR: The metabolism of triglyceride and of cholesteryl ester, in so far as both can be used as core lipids for apoB-containing LPs, are inextricably linked, and the shortage of one or both of these lipids could, by "allowing" increased intracellular degradation in the ER, inhibit the secretion of apo B.
377 citations
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TL;DR: Tolerance, physical dependency, and withdrawal can occur after the prolonged administration of any agent used for sedation and analgesia in the PICU population and treatment options include slowly tapering the intravenous administration or switching to subcutaneous or oral administration.
Abstract: ObjectiveTo describe the consequences of the prolonged administration of sedative and analgesic agents to the pediatric intensive care unit (PICU) patient. The problems to be investigated include tolerance, physical dependency, and withdrawal.Data SourcesA MEDLINE search was performed of literature
377 citations
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TL;DR: A systematic review and meta‐analysis of the oncology‐related literature excluding breast cancer was performed to derive estimates of lymphedema incidence and to identify potential risk factors among various malignancies.
Abstract: BACKGROUND:
Secondary lymphedema is a debilitating, chronic, progressive condition that commonly occurs after the treatment of breast cancer. The purpose of the current study was to perform a systematic review and meta-analysis of the oncology-related literature excluding breast cancer to derive estimates of lymphedema incidence and to identify potential risk factors among various malignancies.
METHODS:
The authors systematically reviewed 3 major medical indices (MEDLINE, Cochrane Library databases, and Scopus) to identify studies (1972-2008) that included a prospective assessment of lymphedema after cancer treatment. Studies were categorized according to malignancy, and data included treatment, complications, lymphedema measurement criteria, lymphedema incidence, and follow-up interval. A quality assessment of individual studies was performed using established criteria for systematic reviews. Bayesian meta-analytic techniques were applied to derive summary estimates when sufficient data were available.
RESULTS:
A total of 47 studies (7779 cancer survivors) met inclusion criteria: melanoma (n = 15), gynecologic malignancies (n = 22), genitourinary cancers (n = 8), head/neck cancers (n = 1), and sarcomas (n = 1). The overall incidence of lymphedema was 15.5% and varied by malignancy (P < .001): melanoma, 16% (upper extremity, 5%; lower extremity, 28%); gynecologic, 20%; genitourinary, 10%; head/neck, 4%; and sarcoma, 30%. Increased lymphedema risk was also noted for patients undergoing pelvic dissections (22%) and radiation therapy (31%). Objective measurement methods and longer follow-up were both associated with increased lymphedema incidence.
CONCLUSIONS:
Lymphedema is a common condition affecting cancer survivors with various malignancies. The incidence of lymphedema is related to the type and extent of treatment, anatomic location, heterogeneity of assessment methods, and length of follow-up. Cancer 2010. © 2010 American Cancer Society.
376 citations
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TL;DR: Results indicate that auxin induces lateral roots and leaf expansion by activating NPH4/ARF7 and ARF19, suggesting that a positive feedback loop regulates leaf expansion and/or lateral root induction.
Abstract: Auxin response factors (ARFs) bind auxin response promoter elements and mediate transcriptional responses to auxin. Five of the 22 ARF genes in Arabidopsis thaliana encode ARFs with glutamine-rich middle domains. Four of these can activate transcription and have been ascribed developmental functions. We show that ARF19, the fifth Q-rich ARF, also activates transcription. Mutations in ARF19 have little effect on their own, but in combination with mutations in NPH4/ARF7, encoding the most closely related ARF, they cause several phenotypes including a drastic decrease in lateral and adventitious root formation and a decrease in leaf cell expansion. These results indicate that auxin induces lateral roots and leaf expansion by activating NPH4/ARF7 and ARF19. Auxin induces the ARF19 gene, and NPH4/ARF7 and ARF19 together are required for expression of one of the arf19 mutant alleles, suggesting that a positive feedback loop regulates leaf expansion and/or lateral root induction.
376 citations
Authors
Showing all 41750 results
Name | H-index | Papers | Citations |
---|---|---|---|
Walter C. Willett | 334 | 2399 | 413322 |
Meir J. Stampfer | 277 | 1414 | 283776 |
Russel J. Reiter | 169 | 1646 | 121010 |
Chad A. Mirkin | 164 | 1078 | 134254 |
Robert Stone | 160 | 1756 | 167901 |
Howard I. Scher | 151 | 944 | 101737 |
Rajesh Kumar | 149 | 4439 | 140830 |
Joseph T. Hupp | 141 | 731 | 82647 |
Lihong V. Wang | 136 | 1118 | 72482 |
Stephen R. Carpenter | 131 | 464 | 109624 |
Jan A. Staessen | 130 | 1137 | 90057 |
Robert S. Brown | 130 | 1243 | 65822 |
Mauro Giavalisco | 128 | 412 | 69967 |
Kenneth J. Pienta | 127 | 671 | 64531 |
Matthew W. Gillman | 126 | 529 | 55835 |