University of Missouri

About: University of Missouri is a education organization based out in Columbia, Missouri, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 41427 authors who have published 83598 publications receiving 2911437 citations. The organization is also known as: Mizzou & Missouri-Columbia.

Deep Eutectic Solvents: A Review of Fundamentals and Applications.

Abstract: Deep eutectic solvents (DESs) are an emerging class of mixtures characterized by significant depressions in melting points compared to those of the neat constituent components. These materials are promising for applications as inexpensive "designer" solvents exhibiting a host of tunable physicochemical properties. A detailed review of the current literature reveals the lack of predictive understanding of the microscopic mechanisms that govern the structure-property relationships in this class of solvents. Complex hydrogen bonding is postulated as the root cause of their melting point depressions and physicochemical properties; to understand these hydrogen bonded networks, it is imperative to study these systems as dynamic entities using both simulations and experiments. This review emphasizes recent research efforts in order to elucidate the next steps needed to develop a fundamental framework needed for a deeper understanding of DESs. It covers recent developments in DES research, frames outstanding scientific questions, and identifies promising research thrusts aligned with the advancement of the field toward predictive models and fundamental understanding of these solvents.

Positive affect and the experience of meaning in life.

Abstract: Six studies examined the role of positive affect (PA) in the experience of meaning in life (MIL). Study 1 showed strong relations between measures of mood, goal appraisals, and MIL. In multivariate analyses, PA was a stronger predictor of MIL than goal appraisals. In Study 2, the most consistent predictor of the experience of meaning in a day was the PA experienced that day. Later, global MIL was predicted by average daily PA, rather than average daily MIL. Study 3 demonstrated no prospective relations between measures of MIL and PA over 2 years. In Study 4, priming positive mood concepts enhanced MIL. In Study 5, manipulated positive mood enhanced ratings of MIL for those who were not given an attributional cue for their moods. In Study 6, PA was associated with a high level of distinction between meaningful and meaningless activities. Results indicate that positive moods may predispose individuals to feel that life is meaningful. In addition, positive moods may increase sensitivity to the meaning-relevance of a situation.

Friction stir processing: a novel technique for fabrication of surface composite

Abstract: A novel surface modifying technique, friction stir processing (FSP), has been developed for fabrication of surface composite. Al–SiC surface composites with different volume fractions of particles were successfully fabricated. The thickness of the surface composite layer ranged from 50 to 200 μm. The SiC particles were uniformly distributed in the aluminum matrix. The surface composites have excellent bonding with the aluminum alloy substrate. The microhardness of the surface composite reinforced with 27vol.%SiC of 0.7 μm average particle size was ∼173 HV, almost double of the 5083Al alloy substrate (85 HV). The solid-state processing and very fine microstructure that results are also desirable for high performance surface composites.

Ventricular pacing or dual-chamber pacing for sinus-node dysfunction

Abstract: Background Dual-chamber (atrioventricular) and single-chamber (ventricular) pacing are alternative treatment approaches for sinus-node dysfunction that causes clinically significant bradycardia. However, it is unknown which type of pacing results in the better outcome. Methods We randomly assigned a total of 2010 patients with sinus-node dysfunction to dual-chamber pacing (1014 patients) or ventricular pacing (996 patients) and followed them for a median of 33.1 months. The primary end point was death from any cause or nonfatal stroke. Secondary end points included the composite of death, stroke, or hospitalization for heart failure; atrial fibrillation; heart-failure score; the pacemaker syndrome; and the quality of life. Results The incidence of the primary end point did not differ significantly between the dual-chamber group (21.5 percent) and the ventricular-paced group (23.0 percent, P=0.48). In patients assigned to dual-chamber pacing, the risk of atrial fibrillation was lower (hazard ratio, 0.79; 9...