University of Missouri

About: University of Missouri is a education organization based out in Columbia, Missouri, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 41427 authors who have published 83598 publications receiving 2911437 citations. The organization is also known as: Mizzou & Missouri-Columbia.

Corporate Divestiture Intensity in Restructuring Firms: Effects of Governance, Strategy, and Performance

Abstract: Both inadequate governance and inappropriate strategy have been proposed as antecedents of the divestment activity of restructuring firms in the 1980s. We combined both views in a structural equati...

Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways

Abstract: Genome-wide association studies (GWAS) of psychiatric disorders have identified multiple genetic associations with such disorders, but better methods are needed to derive the underlying biological mechanisms that these signals indicate. We sought to identify biological pathways in GWAS data from over 60,000 participants from the Psychiatric Genomics Consortium. We developed an analysis framework to rank pathways that requires only summary statistics. We combined this score across disorders to find common pathways across three adult psychiatric disorders: schizophrenia, major depression and bipolar disorder. Histone methylation processes showed the strongest association, and we also found statistically significant evidence for associations with multiple immune and neuronal signaling pathways and with the postsynaptic density. Our study indicates that risk variants for psychiatric disorders aggregate in particular biological pathways and that these pathways are frequently shared between disorders. Our results confirm known mechanisms and suggest several novel insights into the etiology of psychiatric disorders.

Radio tracking and animal populations

Abstract: Publisher Summary Steady technological advancements including subminiaturization of telemetry components, smaller and more accurate global positioning systems (GPSs), and increasingly available geographic information systems (GISs) continue to influence the way researchers collect and analyze wildlife radio-tracking data. These developments have increased the diversity of animals that can be studied and have boosted the number and accuracy of location estimates, within a framework of contemporary conservation issues. This chapter conducts a literature review using the Wildlife Worldwide (WW) database to assess the specific topics and number of studies using radiotelemetry in wildlife research. Databases within the WW search engine include Wildlife Review Abstracts (formerly Wildlife Review), Swiss Wildlife Information Service, Wildlife Database, BIODOC, and the Waterfowl and Wetlands database. The most critical assumption in any radiotelemetry study is that the transmitter has no appreciable effect on the study animal. One can assume that a marked animal behaves, functions, and survives in a manner similar to that of an unmarked animal. Despite this critical assumption, the impact of radio marking of animals has often been subjectively evaluated. Generally, researchers assume that large animals are not affected by radio marking, whereas smaller animals, particularly birds, are impacted more.