University of Nebraska Omaha

About: University of Nebraska Omaha is a education organization based out in Omaha, Nebraska, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 4526 authors who have published 8905 publications receiving 213914 citations. The organization is also known as: UNO & University of Omaha.

Rules of Crowdsourcing: Models, Issues, and Systems of Control

Abstract: In this article, the authors first provide a practical yet rigorous definition of crowdsourcing that incorporates “crowds,” outsourcing, and social web technologies. They then analyze 103 well-known crowdsourcing web sites using content analysis methods and the hermeneutic reading principle. Based on their analysis, they develop a “taxonomic theory” of crowdsourcing by organizing the empirical variants in nine distinct forms of crowdsourcing models. They also discuss key issues and directions, concentrating on the notion of managerial control systems.

Physiological demands of competitive basketball.

Abstract: The aim of this study was to assess physiological demands of competitive basketball by measuring oxygen consumption (VO2) and other variables during practice games. Each of 12 players (20.4 � 1.1 years) was monitored in a 20-min practice game, which was conducted in the same way as actual games with the presence of referees and coaches. VO2 was measured by a portable system during the game and blood lactate concentration (LA) was measured in brief breaks. Subjects were also videotaped for time-motion analysis. Female and male players demonstrated respective VO2 of 33.4 � 4.0 and 36.9 � 2.6 mL/kg/min and LA of 3.2 � 0.9 and 4.2 � 1.3 mmol/L in the practice games (P40.05). They spent 34.1% of play time running and jumping, 56.8% walking, and 9.0% standing. Pre-obtained VO2max was correlated to VO2 during play (r 5 0.673) and to percent of duration for running and jumping (r 5 0.935 and 0.962 for females and males, respectively). This study demonstrated a greater oxygen uptake for competitive basketball than that estimated based on a previous compendium. The correlation between aerobic capacity and activity level suggests the potential benefit of aerobic conditioning in basketball.

CD4+ regulatory and effector/memory T cell subsets profile motor dysfunction in Parkinson's disease.

Abstract: Animal models and clinical studies have linked the innate and adaptive immune system to the pathology of Parkinson’s disease (PD). Despite such progress, the specific immune responses that influence disease progression have eluded investigators. Herein, we assessed relationships between T cell phenotype and function with PD progression. Peripheral blood lymphocytes from two separate cohorts, a discovery cohort and a validation cohort, totaling 113 PD patients and 96 age- and environment-matched caregivers were examined by flow cytometric analysis and T cell proliferation assays. Increased effector/memory T cells (Tem), defined as CD45RO+ and FAS+ CD4+ T cells and decreased CD31+ and α4β7+ CD4+ T cells were associated with progressive Unified Parkinson’s Disease Rating Scale III scores. However, no associations were seen between immune biomarkers and increased age or disease duration. Impaired abilities of regulatory T cells (Treg) from PD patients to suppress effector T cell function was observed. These data support the concept that chronic immune stimulation, notably Tem activation and Treg dysfunction is linked to PD pathobiology and disease severity, but not disease duration. The association of T cell phenotypes with motor symptoms provides fresh avenues for novel biomarkers and therapeutic designs.