Journal ArticleDOI
.alpha.-Methoxy-.alpha.-trifluoromethylphenylacetic acid, a versatile reagent for the determination of enantiomeric composition of alcohols and amines
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This article is published in Journal of Organic Chemistry.The article was published on 1969-09-01. It has received 2312 citations till now. The article focuses on the topics: Reagent.read more
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Separation of Optical Isomers as Diastereomeric Derivatives by High Performance Liquid Chromatography
TL;DR: In this paper, the authors proposed a method to distinguish or resolve enantiomeric isomers, especially in biochemical and pharmaceutical applications, using optical isomers occuring widely in nature.
Journal ArticleDOI
A New Asymmetric Carbon–Carbon Bond Forming Reaction: Four‐Component Stereoselective Synthesis of (Z)‐4,6‐Dihydroxy‐3‐methylalk‐2‐enyl Methyl Sulfones
TL;DR: In this paper, asymmetric synthesis of polyketides and sulfones was investigated. But the results were limited to the case of Hetero-Diels-Alder (HDE) and sulfur dioxide.
Journal ArticleDOI
The relation between biological activity and the degree of resolution of optical isomers.
TL;DR: This biological method for assessing stereochemical purity is likely to be at least as satisfactory as any nuclear magnetic resonance method currently in use, because of the very great sensitivity of the stereospecific index to the degree of resolution.
Journal ArticleDOI
Recent Development on Spectroscopic Methods for Chiral Analysis of Enantiomeric Compounds
TL;DR: A survey of the literature suggests that different spectroscopic methods are applied to achieve the analysis of chiral enantiomeric compounds as mentioned in this paper, which is an important task in the field of analytical chemistry.
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Nuclear magnetic resonance enantiomer regents. Configurational correlations via nuclear magnetic resonance chemical shifts of diastereomeric mandelate, O-methylmandelate, and .alpha.-methoxy-.alpha.-trifluoromethylphenylacetate (MTPA) esters
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