Journal ArticleDOI
.alpha.-Methoxy-.alpha.-trifluoromethylphenylacetic acid, a versatile reagent for the determination of enantiomeric composition of alcohols and amines
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This article is published in Journal of Organic Chemistry.The article was published on 1969-09-01. It has received 2312 citations till now. The article focuses on the topics: Reagent.read more
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Chiral leaving group asymmetric synthesis of limonene and bisabolene
TL;DR: In this paper, a biogenetic-type asymmetric synthesis of limonene and bisabolenes is described, where the metal-anchimeric assistance of the aluminum reagents bound with the neighboring hydroxyl group is used for effecting the generation of the allyl cation.
Journal ArticleDOI
An Improved Synthetic Method of (S)-2-Alkoxypropanals from Ethyl (S)-Lactate
TL;DR: In this paper, the title synthetic method which undergoes without racemization, was explored employing sequential amidolysis with a secondary amine, alkylation with an alkyl halide under basic conditions, and reduction with sodium bis(methoxyethoxy)aluminium hydride.
Journal ArticleDOI
Enantioselective synthesis of (S)- and (R)-6-hydroxy-8-nonene-carboxylates by asymmetric catalysis: a formal synthesis of (R)-α-lipoic acid and its (S)-antipode
TL;DR: In this article, a short and efficient enantioselective synthesis of (S)- and (R)-configured 6-hydroxy-8-nonene-carboxylates by allylation of alkoxycarbonyl substituted aldehydes with allyltrimethylstannane and BINOL/Ti(OiPr)4 catalyst is described.
Journal ArticleDOI
Investigation of the Chemo‐ and Stereoselectivity of the Ketene‐Claisen Rearrangement
TL;DR: In this article, a novel type of ketene-Claisen rearrangement in which the precursor is generated in situ by reaction of optically active allyl thioethers with dichloroketene is described.
Journal ArticleDOI
Enantioselective 2,3 sigmatropic rearrangement mediated by a butyllithium-chiral ligand complex
TL;DR: The first enantioselective [2,3] sigmropic rearrangement of acyclic======diprop-2-ynyl ethers and alkenyl benzyl ether was achieved by a ∼BuLi−chiral ligand complex as mentioned in this paper.
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Nuclear magnetic resonance enantiomer regents. Configurational correlations via nuclear magnetic resonance chemical shifts of diastereomeric mandelate, O-methylmandelate, and .alpha.-methoxy-.alpha.-trifluoromethylphenylacetate (MTPA) esters
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