Journal ArticleDOI
.alpha.-Methoxy-.alpha.-trifluoromethylphenylacetic acid, a versatile reagent for the determination of enantiomeric composition of alcohols and amines
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This article is published in Journal of Organic Chemistry.The article was published on 1969-09-01. It has received 2312 citations till now. The article focuses on the topics: Reagent.read more
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Desymmetrization of meso-1,2-diols via chiral oxazaborolidine-mediated ring-cleavage of acetal derivatives with silyl ketene S,O-acetal
TL;DR: In this paper, the asymmetrization of meso-1,2-diols leading to enantiomerically enriched MOM and MEM ethers is realized via chiral oxazaborolidine-mediated enantioselective ring-cleavage reaction of the acetal derivatives with silyl ketene.
Journal ArticleDOI
Direct transformation of 2,3-epoxy alcohols into hydroxy carbonates under mildly basic conditions
TL;DR: In this paper, 2,3-Epoxy alcohols are transformed into the corresponding C2-inverted hydroxy carbonates upon treatment with cesium carbonate-powdered 3-A molecular sieves in N,N-dimethylformamide under one atmosphere of carbon dioxide at 23 −78 °C.
Journal ArticleDOI
31P NMR assays for rapid determination of enantiomeric excess in catalytic hydrosilylations and transfer hydrogenations
TL;DR: Chiral chlorophosphine (S )-(1,1′-binaphthalen-2,2′-dioxy)chlorophosphines (S)-2 was tested for its performance as a chiral-derivatizing agent (CDA) using solutions of various alcohols, amines, and N -BOC amino acids.
Journal ArticleDOI
4-benzyl-2,3-didehydroprolinate as a homochiral template for michael additions. Synthesis of enantiopure α-allokainoids, β-kainoids, 2,3-methanoprolines and other 3,4-disubstituted prolines
TL;DR: In this paper, the enantiopure β-kainoid 5a and 2,3-methanoproline 15.10a undergoes Michael additions with stabilized carbanions and cuprates giving exclusively the all-trans 3,4-disubstituted prolinates.
Journal ArticleDOI
Studies on novel and chiral 1,4-dihydropyridines. III. Asymmetric reduction of some ketones with novel NADH model compounds, (SS)-3-(p-Tolylsulfinyl)-1,4-dihydropyridines
Satoshi Obika,Toshihiko Nishiyama,S. Tatematsu,Kazuyuki Miyashita,Chuzo Iwata,Takeshi Imanishi +5 more
TL;DR: In this article, the reactions of the novel NADH model compounds with methyl benzoylformate and some other ketonic compounds were studied and a possible transition state model was discussed.
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Nuclear magnetic resonance enantiomer regents. Configurational correlations via nuclear magnetic resonance chemical shifts of diastereomeric mandelate, O-methylmandelate, and .alpha.-methoxy-.alpha.-trifluoromethylphenylacetate (MTPA) esters
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