Journal ArticleDOI
.alpha.-Methoxy-.alpha.-trifluoromethylphenylacetic acid, a versatile reagent for the determination of enantiomeric composition of alcohols and amines
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This article is published in Journal of Organic Chemistry.The article was published on 1969-09-01. It has received 2312 citations till now. The article focuses on the topics: Reagent.read more
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Asymmetric synthesis via chiral acetal templates. 7. Further studies on the cyanation reaction. The use of acetals derived from diols with one chiral center
TL;DR: New examples of the cyanation reaction are described in this article, including one that affords the cyanochydrin 8, an intermediate for synthesizing pyrethroid insecticides.
Journal ArticleDOI
Chemical and Electrochemical Asymmetric Dihydroxylation of Olefins in I(2)-K(2)CO(3)-K(2)OsO(2)(OH)(4) and I(2)-K(3)PO(4)/K(2)HPO(4)-K(2)OsO(2)(OH)(4) Systems with Sharpless' Ligand.
TL;DR: In this article, the potentiality of I(2) as a co-oxidant under stoichiometric conditions has been proven to be effective as an oxidizing mediator in electrolysis systems.
Journal ArticleDOI
Synthesis of 3-substituted benzamides and 5-substituted isoquinolin-1(2H)-ones and preliminary evaluation as inhibitors of poly(ADP-ribose)polymerase (PARP).
TL;DR: 3-Oxiranylbenzamide, 5-bromoisoquinolin-1-one and 5-iodoisoquolin- 1-one were among the most potent inhibitors of PARP activity in a preliminary screen in vitro.
Journal ArticleDOI
Enzymatic resolution of norbornane-type esters
TL;DR: In this article, a short and efficient access to a number of chiral building blocks on a molar scale for the synthesis of optically active cyclopentane systems was presented.
Journal ArticleDOI
Total Synthesis of Tricolorin A.
TL;DR: Tricolorin A (1) is a novel tetrasaccharide macrolactone that is a natural herbicide that can be synthesized in 14 steps as discussed by the authors.
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Nuclear magnetic resonance enantiomer regents. Configurational correlations via nuclear magnetic resonance chemical shifts of diastereomeric mandelate, O-methylmandelate, and .alpha.-methoxy-.alpha.-trifluoromethylphenylacetate (MTPA) esters
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