Journal ArticleDOI
.alpha.-Methoxy-.alpha.-trifluoromethylphenylacetic acid, a versatile reagent for the determination of enantiomeric composition of alcohols and amines
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This article is published in Journal of Organic Chemistry.The article was published on 1969-09-01. It has received 2312 citations till now. The article focuses on the topics: Reagent.read more
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Highly asymmetric enzymatic hydrolysis and transesterification of meso-biscacetoxymethyl)- and bis(hydroxymethyl)cyclopentane derivatives: an insight into the active site model of Rhizopus Delemar lipase
TL;DR: In this article, the simple box-type active site model of enzyme was tentatively proposed to explain the high enantioselectivities of RDL and Pseudomonas fluorescens lipase (PFL) for meso -bis-(hydroxymethyl) cyclopentane derivatives.
Journal ArticleDOI
Synthesis of all of the four possible stereoisomers of pestalotin, a gibberellin synergist isolated from Pestalotia cryptomeriaecola Sawada
TL;DR: Pestalotin and its three other stereoisomers were synthesized either by utilizing the Sharpless asymmetric epoxidation as the keystep or by derivation from D-(+)-glyceraldehyde acetonide.
Journal ArticleDOI
Preparation of enantiomerically pure (1S,2S)-1-aminocyclopropanephosphonic acid from methylcyclopropanone acetal via spirophosphonate intermediates
Antoine Fadel,Nicolas Tesson +1 more
TL;DR: An easy and efficient one-pot reaction from readily available methylcyclopropanone acetal (2 S )- 4b gave the spirophosphonates 8a-b with excellent diastereoselectivity as mentioned in this paper.
Journal ArticleDOI
Synthesis of optically active diols using an efficient polymer bound cinchona alkaloid derivative
TL;DR: In this paper, a new insoluble polymer containing a Cinchona alkaloid derivative has been synthesized and used as chiral ligand in the heterogeneous enantioselective dihydroxylation of olefins.
Journal ArticleDOI
Synthesis of the C21-C28 segment of pectenotoxin-4
TL;DR: In this paper, the synthesis of the C21-C28 segment of pectenotoxin-4 as the Weinreb amide is described, and the feasibility studies for the union of a related Weinberger amide and a functionalized alkyne are also reported.
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Nuclear magnetic resonance enantiomer regents. Configurational correlations via nuclear magnetic resonance chemical shifts of diastereomeric mandelate, O-methylmandelate, and .alpha.-methoxy-.alpha.-trifluoromethylphenylacetate (MTPA) esters
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