Journal ArticleDOI
.alpha.-Methoxy-.alpha.-trifluoromethylphenylacetic acid, a versatile reagent for the determination of enantiomeric composition of alcohols and amines
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This article is published in Journal of Organic Chemistry.The article was published on 1969-09-01. It has received 2312 citations till now. The article focuses on the topics: Reagent.read more
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Synthesis of (−)-(4R,5R)-muricatacin using a regio- and stereospecific ring-opening of a vinyl epoxide
TL;DR: In this paper, the total synthesis of (−)-muricatacin, a natural acetogenin, has been achieved using as a key step a regio-and stereospecific ring-opening of a substituted vinyl epoxide under Lewis acid catalysis.
Journal ArticleDOI
Asymmetric synthesis of 4-[(t-butoxycarbonyl)amino]-pyrazolidin-3-one : precursor to bicyclic pyrazolidinone antibacterials
TL;DR: In this paper, the preparation of chiral pyrazolidin-3-one 1 was described, and the key step was cyclization via a Mitsunobu reaction using the trifluoroacetyl group to activate the terminal nitrogen.
Journal ArticleDOI
Stereoselective alkylation of chiral glycine enolate synthons. The enantioselective synthesis of α-amino acid derivatives.
TL;DR: In this article, the highly stereoselective alkylation of a chiral glycine enolate synthon derived from D-2-phenylglycinol is described.
Journal ArticleDOI
The chemistry of substituted pyrazolidinones; applications to the synthesis of bicyclic derivatives
TL;DR: In this article, the selective chemical derivatizations of substituted pyrazolidinones are described, and the application of these methods to the preparation of [4.3.0] and bicyclic systems is also discussed.
Journal ArticleDOI
Enantioselective trimethylsilylcyanation of some aldehydes promoted by modified sharpless catalyst
TL;DR: In this paper, a highly enantioselective method for trimethylsilylcyanation of a variety of aldehydes was developed using a modified Sharpless reagent.
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Nuclear magnetic resonance enantiomer regents. Configurational correlations via nuclear magnetic resonance chemical shifts of diastereomeric mandelate, O-methylmandelate, and .alpha.-methoxy-.alpha.-trifluoromethylphenylacetate (MTPA) esters
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