Journal ArticleDOI
.alpha.-Methoxy-.alpha.-trifluoromethylphenylacetic acid, a versatile reagent for the determination of enantiomeric composition of alcohols and amines
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This article is published in Journal of Organic Chemistry.The article was published on 1969-09-01. It has received 2312 citations till now. The article focuses on the topics: Reagent.read more
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Totalsynthese des Thiazolylpeptids GE2270 A
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A versatile approach to pyrimidin-4-yl substituted α-aminoacids from alkynyl ketones; the total synthesis of l-lathyrine
TL;DR: A range of pyrimidin-4-yl substituted α-amino acids has been synthesised by the reaction of amidines with α- amino acid alkynyl ketones.
Journal ArticleDOI
Enantioselective Synthesis of (−)-Canadensolide
TL;DR: Chiral synthesis of canadensolide has been achieved by using the Sharpless kinetic resolution of the 2-furylcarbinol derivative( 11 ), followed by its oxidative conversion into the corresponding pyranone( 12 ) as key reactions.
Journal ArticleDOI
Reductive pinacol-type rearrangement of chiral α-mesyloxy ketones promoted by organoaluminum compounds
TL;DR: Reductive pinacol-type rearrangement of chiral α-mesyloxy ketones was effected by organoaluminums (DIBAL in combination with Et 3 Al or Et 2 AlCl) leading to enantiomerically pure 2-aryl- or 2-alkenyl-1-propanols.
Journal ArticleDOI
Asymmetric synthesis of primary amines from alkenes and chiral chloronitroso sugar derivatives
TL;DR: In this paper, a variety of alkenes 5 -15, 38, 39 react with chloronitroso sugar derivatives 1 - 3 regioselectively at ambient temperature to give chiral hydroxylamines m 60 - 80% yield.
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