Journal ArticleDOI
.alpha.-Methoxy-.alpha.-trifluoromethylphenylacetic acid, a versatile reagent for the determination of enantiomeric composition of alcohols and amines
About:
This article is published in Journal of Organic Chemistry.The article was published on 1969-09-01. It has received 2312 citations till now. The article focuses on the topics: Reagent.read more
Citations
More filters
Journal ArticleDOI
Biotransformation of α- and β-ionones by immobilized cells of Nicotiana tabacum
Yi-Xiong Tang,Takayuki Suga +1 more
TL;DR: The selectivity for the reduction of the double bond adjacent to the carbonyl group could be enhanced by performing the biotransformation in medium with a pH near the optimal pH of the enone reductase which specifically catalyses the reductionof the alpha, beta-unsaturated double bond of s-trans-enones.
Journal ArticleDOI
(S)-Pyroglutamic acid, (S)-malic acid and (S)-serine as useful starting materials in the synthesis of enantiopure hydroxyamidines.
TL;DR: In this article, the synthesis of enantiopure hydroxyamidines is described, and the key step involved the addition of phenylmagnesium bromide to the corresponding ester, affording the tertiary alcohol without detectable racemization.
Journal ArticleDOI
Asymmetric synthesis of both enantiomers of vigabatrin®: An approach using methionine as the chiral pool
Wei Zhong-Yong,Edward E. Knaus +1 more
TL;DR: Both enantiomers of the potent GABA-T inhibitor, 4-amino-5-hexenoic acid (2), were prepared in five steps from (R)- or (S)-methionine using a one-pot reduction-homologation of an αamino ester as the key reaction step as discussed by the authors.
Journal ArticleDOI
Isolation, identification, synthesis, and bioassay of the pheromone of the comstock mealybug and some analogs.
B. A. Bierl-Leonhardt,D. S. Moreno,Meyer Schwarz,Harold S. Forster,J. R. Plimmer,E. D. DeVilbiss +5 more
TL;DR: The sex pheromone of the Comstock mealybug,Pseudococcus comstocki (Kuwana) was isolated from volatiles trapped from air passing over virgin female insects and the structure was 2,6-dimethyl-1,5-heptadien-3-ol acetate.
Journal ArticleDOI
Chirality transfer in palladium catalyzed reactions of allylammonium salts
TL;DR: Optically active 1-isobutyl-2(Z)-butenyltrimethylammonium iodide (10) underwent allylation with dimethyl sodiomalonate in the presence of a palladium(0) catalyst as mentioned in this paper.
Related Papers (5)
Nuclear magnetic resonance enantiomer regents. Configurational correlations via nuclear magnetic resonance chemical shifts of diastereomeric mandelate, O-methylmandelate, and .alpha.-methoxy-.alpha.-trifluoromethylphenylacetate (MTPA) esters
James A. Dale,Harry S. Mosher +1 more