Journal ArticleDOI
.alpha.-Methoxy-.alpha.-trifluoromethylphenylacetic acid, a versatile reagent for the determination of enantiomeric composition of alcohols and amines
About:
This article is published in Journal of Organic Chemistry.The article was published on 1969-09-01. It has received 2312 citations till now. The article focuses on the topics: Reagent.read more
Citations
More filters
Journal ArticleDOI
The palladium-catalyzed arylation of 4H-1,3-dioxin
TL;DR: In this paper, 4 H -1,3-Dioxin was firstly arylated by using Heck reaction, and the reaction in the presence of ( R )-BINAP gave enantiomerically enriched 4-phenyldioxin which was converted into optically active 1-phenyl-1, 3-propanediol.
Journal ArticleDOI
A Rapid Synthesis of Hydroxymethylacylfulvene (HMAF) Using the Allenic Pauson−Khand Reaction. A Synthetic Approach to Either Enantiomer of This Illudane Structure
TL;DR: In this article, an allenic Pauson−Khand reaction has been employed in the preparation of (±)-hydroxymethylacylfulvene (HMAF), an anticancer agent that is currently in Phase II clinical trials for a variety of solid tumor types.
Journal ArticleDOI
Phyllostictines A–D, oxazatricycloalkenones produced by Phyllosticta cirsii, a potential mycoherbicide for Cirsium arvense biocontrol
Antonio Evidente,Alessio Cimmino,Anna Andolfi,Maurizio Vurro,Maria Chiara Zonno,Charles L. Cantrell,Andrea Motta +6 more
TL;DR: In this paper, a fungal pathogen isolated from Cirsium arvense and proposed as biocontrol agent of this noxious perennial weed, produces in liquid cultures different phytotoxic metabolites with potential herbicidal activity.
Journal ArticleDOI
Biologically active glycosides from asteroidea, XV. Asymmetric synthesis of phytosphingosine and phytosphingosine anhydro base: Assignment of the absolute stereochemistry
TL;DR: The first asymmetric synthesis of a phytosphingosine, (2S,3S,4R)-2amino-1,3,4-hexadecanetriol (2), was accomplished by kinetic resolution and asymmetric epoxidation as mentioned in this paper.
Journal ArticleDOI
The synthesis of either (+) or (−) trans-2,5-dimethylpyrrolidine
TL;DR: Trans -2,5-dimethylpyrrolidine, in either optical series, is prepared starting from D or L -alanine in an efficient and reasonably brief reaction sequence as mentioned in this paper.
Related Papers (5)
Nuclear magnetic resonance enantiomer regents. Configurational correlations via nuclear magnetic resonance chemical shifts of diastereomeric mandelate, O-methylmandelate, and .alpha.-methoxy-.alpha.-trifluoromethylphenylacetate (MTPA) esters
James A. Dale,Harry S. Mosher +1 more