Journal ArticleDOI
.alpha.-Methoxy-.alpha.-trifluoromethylphenylacetic acid, a versatile reagent for the determination of enantiomeric composition of alcohols and amines
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This article is published in Journal of Organic Chemistry.The article was published on 1969-09-01. It has received 2312 citations till now. The article focuses on the topics: Reagent.read more
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The synthesis of novel heterocyclic substituted α-amino acids; further exploitation of α-amino acid alkynyl ketones as reactive substrates
TL;DR: A series of novel non-proteinogenic heterocyclic substituted α-amino acids derived from L-aspartic acid have been synthesised using the alkynyl ketone functionality as a versatile building block as discussed by the authors.
Journal ArticleDOI
Asymmetrische reduktive Aminierung von Cycloalkanonen, 5. Synthese und absolute Konfiguration 2‐substituierter Cyclopentanamine
Wolfgang Wiehl,August W. Frahm +1 more
TL;DR: In this paper, an asymmetric synthesis of 2-substituted cyclohexanamines from racemic cycloenanones by means of reductive amination in a three-step procedure is described.
Journal ArticleDOI
Synthesis of novel acridino- and phenazino-18-crown-6 ligands and their optically pure dimethyl-substituted analogues for molecular recognition studies
Péter Huszthy,Erika Samu,Borbála Vermes,Gabriella Mezey-Vándor,Mihály Nógrádi,Jerald S. Bradshaw,Reed M. Izatt +6 more
TL;DR: In this paper, a novel acridino-and phenazino-18-crown-6 ligands were obtained from tetraethylene glycol di-p-tosylate using potassium teri-butoxide as a base in THF.
Journal ArticleDOI
Asymmetric-synthesis x: a chiral pyrrolidine synthon for a new approach to the synthesis of alkaloids
TL;DR: In this article, the synthesis of chiral 2-cyano-5-oxazolopyrrolidine 3 was reported, and the optically pure ant venom alkolaid, (+)-(S)- trans -2-heptyl-5butyl-pyrrolididine 7, has been achieved from 3.
Journal ArticleDOI
The total synthesis of (+)-pectinatone: An iterative alkylation approach based on the SAMP-hydrazone method
Anthony A Birkbeck,Dieter Enders +1 more
TL;DR: The marine natural product (+)-pectinatone containing 1,3dimethyl stereocentres was synthesized via the iterative alkylation of propanal SAMP-hydrazone with β-branched iodides.
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Nuclear magnetic resonance enantiomer regents. Configurational correlations via nuclear magnetic resonance chemical shifts of diastereomeric mandelate, O-methylmandelate, and .alpha.-methoxy-.alpha.-trifluoromethylphenylacetate (MTPA) esters
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