Journal ArticleDOI
.alpha.-Methoxy-.alpha.-trifluoromethylphenylacetic acid, a versatile reagent for the determination of enantiomeric composition of alcohols and amines
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This article is published in Journal of Organic Chemistry.The article was published on 1969-09-01. It has received 2312 citations till now. The article focuses on the topics: Reagent.read more
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A Highly Diastereoselective Synthesis of (1R)-(+)-Camphor-Based Chiral Allenes and Their Asymmetric Hydroboration−Oxidation Reactions†
TL;DR: Reaction of (1R)-(+)-camphor with alkynyllithium followed by the reduction of the resulted propargyl alcohol derivatives using AlH3 furnished chiral allenes 2a-g in excellent yields with high diastereoselectivity are described.
Journal ArticleDOI
Stereoselectivity of hydrogen transfer with chiral NADH models as a function of configuration and conformation
TL;DR: In this paper, the NMR spectra of these compounds and their precursors were studied from which it could be assumed that model 2 and its derivatives could have two conformers due to the restricted rotation of the amide moiety.
Journal ArticleDOI
A modified synthesis of mosher's acid and its use in a sensitive stereoisomer analysis of amino acid derivatives
TL;DR: In this article, a method for stereoisomer analysis of amino acid derivatives is described based on 19 F NMR-analysis of mixtures containing epimers of N-methoxy-.-trifluoromethyl-phenylacetyl alanine (MTPA).
Journal ArticleDOI
Branched chain mono-glycerol ethers from a taiwanese marine sponge of the genus Aaptos
Muu N. Do,Karen L. Erickson +1 more
TL;DR: In this article, 3-(13-Methylhexadecyloxy)-1,2-(S)-propanediol (6 ) and 3-(15-methyl octadecyloxyloxy)- 1,2-S)-polypropanediol (7 ) were isolated from an Aaptos species of marine sponge from Taiwanese waters and characterized by spectroscopic methods.
Journal ArticleDOI
Enantioselective total synthesis of (+)-nitramine
David Tanner,Hua Ming He +1 more
TL;DR: In this paper, a short enantioselective synthesis of the spirocyclic alkaloid (+)-Nitramine (1) was reported, the azaspiro ring system being formed via intramolecular ring-opening of the chiral epoxy sulfone 7
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Nuclear magnetic resonance enantiomer regents. Configurational correlations via nuclear magnetic resonance chemical shifts of diastereomeric mandelate, O-methylmandelate, and .alpha.-methoxy-.alpha.-trifluoromethylphenylacetate (MTPA) esters
James A. Dale,Harry S. Mosher +1 more