Journal ArticleDOI
.alpha.-Methoxy-.alpha.-trifluoromethylphenylacetic acid, a versatile reagent for the determination of enantiomeric composition of alcohols and amines
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This article is published in Journal of Organic Chemistry.The article was published on 1969-09-01. It has received 2312 citations till now. The article focuses on the topics: Reagent.read more
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Enantio- and Diastereo-Selective Synthesis of (+)-Grandisol
TL;DR: In this article, Grandisol, an insect pheromone having cyclobutane skeleton, is synthesized enantio- and diastereo selectively, using the asymmetric [2+2] cycloaddition reaction.
Journal ArticleDOI
A practical synthesis of (S)-HPMPC
TL;DR: Synthesis of the title nucleotide was accomplished in high yield starting from (S)-tritylglycidol (5 ) and N-benzoylcytosine (9 ) as mentioned in this paper.
Journal ArticleDOI
Preparation of optically active 2-aminoalkylphosphinic and phosphonic acids
TL;DR: The reaction of sodium alkylphosphinates with tosylamino tosylates of amino alcohols derived from 1-aminoalkylcar☐ylic acids gives high yields of optically active 2-tosylamino-alkylphosphinic or phosphonic esters.
Journal ArticleDOI
Preparative-scale kinetic resolutions catalysed by microbial lipases immobilised in AOT-stabilised microemulsion-based organogels: cryoenzymology as a tool for improving enantioselectivity
TL;DR: Gelatin-containing microemulsion based organogels have been used as an immobilisation matrix for lipases from a number of different sources and selectively esterified the (R)-(-) isomer of racemic octan-3-ol, yielding product with an enantiomeric excess of 90%.
Journal ArticleDOI
Total synthesis of an enantiomeric pair of FR900482. 2. Syntheses of the aromatic and the optically active aliphatic segments
TL;DR: In this paper, the synthesis of the aromatic segment 4 was achieved starting from commercially available 5-hydroxyisophthalic acid (6) by utilizing Claisen rearrangement of 9, bromolactonization of 12, and modified Curtius rearrangements of 16 as the key steps.
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Nuclear magnetic resonance enantiomer regents. Configurational correlations via nuclear magnetic resonance chemical shifts of diastereomeric mandelate, O-methylmandelate, and .alpha.-methoxy-.alpha.-trifluoromethylphenylacetate (MTPA) esters
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