Journal ArticleDOI
.alpha.-Methoxy-.alpha.-trifluoromethylphenylacetic acid, a versatile reagent for the determination of enantiomeric composition of alcohols and amines
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This article is published in Journal of Organic Chemistry.The article was published on 1969-09-01. It has received 2312 citations till now. The article focuses on the topics: Reagent.read more
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Enzymatic kinetic resolution of a functionalized 4-hydroxy-cyclopentenone: synthesis of the key intermediates in the total synthesis of isoprostanes
TL;DR: In this paper, the enzymatic kinetic resolution of racemic alcohol 4-hydroxy-cyclopentenone was investigated using four different lipases for enantioselective transacetylation, as well as for enantislective hydrolysis, leading to the pure (R)- and (S)-enantiomers.
Journal ArticleDOI
Preparation of the enantiomers of the analgesic E-3710.
TL;DR: In this paper, the enantiomers of E-3710, a novel analgesic, were prepared by a practical resolution method and their absollute stereochemistries assigned by asymmetric synthesis from ethyl (R) -mandelate.
Journal Article
Disinction of enantiomers by NMR spectroscopy using chiral orienting media
TL;DR: A review of the techniques being developed for enantiomeric differentiation by virtue of chiral alignment media and their induction of anisotropic NMR parameters like residual dipolar couplings can be found in this article.
Journal ArticleDOI
Stereoselective synthesis of (2S,3S)-3-N-benzylaminoprolinol and (7S,8R)-7-N-benzylaminopyrrolizidin-3-one
TL;DR: In this paper, the synthesis of (2S, 3S)-3S)-N-benzylaminoprolinol and derivatives involved the conjugate addition of N-benzine to α,β-unsaturated lactam 2.
Journal ArticleDOI
Kinetic Resolution of α-Arylcarboxylic Acid Derivatives by a Catalytic Use of a Chiral Titanium Alkoxide
TL;DR: In this article, a catalytic use of titanium tetraisopropoxide and a chiral 1,4-diol in the reaction of the corresponding 2-pyridinethiol esters and isopropyl alcohol is described.
Related Papers (5)
Nuclear magnetic resonance enantiomer regents. Configurational correlations via nuclear magnetic resonance chemical shifts of diastereomeric mandelate, O-methylmandelate, and .alpha.-methoxy-.alpha.-trifluoromethylphenylacetate (MTPA) esters
James A. Dale,Harry S. Mosher +1 more