Journal ArticleDOI
.alpha.-Methoxy-.alpha.-trifluoromethylphenylacetic acid, a versatile reagent for the determination of enantiomeric composition of alcohols and amines
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This article is published in Journal of Organic Chemistry.The article was published on 1969-09-01. It has received 2312 citations till now. The article focuses on the topics: Reagent.read more
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α-Amino-α-trifluoromethyl-phenylacetonitrile: A potential reagent for 19F NMR determination of enantiomeric purity of acids
TL;DR: In this article, the amino group is used as a potential reagent for the 19 F NMR determination of enantiomeric purity of chiral acids by conversion to their corresponding diastereomeric amides.
Journal ArticleDOI
Stereospecific Synthesis of Chlamydocin
TL;DR: In this paper, a stereospecific synthesis of the cyclic tetrapeptide chlamydocin via free radical homologation from a (S )-2-amino-5-iodopentanoic acid containing cyclic peptide is described.
Journal ArticleDOI
A convenient “one-pot” synthesis of epoxy alcohols via photooxygenation of olefins in the presence of titanium(IV) catalyst
TL;DR: The ene reaction of singlet oxygen with alkenes in the presence of titanium alkoxides was employed to prepare epoxy alcohols in high diastereoselectivity.
Journal ArticleDOI
Stereoselektive Synthese von Alkoholen, XVIII. Synthese von (3S,4S)-4-Methyl-3-heptanol und von (5S,6S)-Anhydroserricornin
TL;DR: In this paper, a reduction of methyl tetrahydro-4-oxo-2H-thiopyran-3-carboxylate (5) led to the β-hydroxy ester 6 of 98% diastereomeric and ca. 85% enantiomeric purity.
Journal ArticleDOI
Intramolecular aromatic nucleophilic substitution of the benzimidazole-activated nitro group.
TL;DR: A wide range of 2-(2-nitrophenyl)-1H-benzimidazoles undergo high-yielding intramolecular S(N)Ar of nitrite with N-pendant alkoxides under mild conditions (DMF, rt) and are converted to the corresponding N-vinyl-substituted 2-hydroxyphenyl-1H, via base-catalyzed isomerization.
Related Papers (5)
Nuclear magnetic resonance enantiomer regents. Configurational correlations via nuclear magnetic resonance chemical shifts of diastereomeric mandelate, O-methylmandelate, and .alpha.-methoxy-.alpha.-trifluoromethylphenylacetate (MTPA) esters
James A. Dale,Harry S. Mosher +1 more