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Journal ArticleDOI

.alpha.-Methoxy-.alpha.-trifluoromethylphenylacetic acid, a versatile reagent for the determination of enantiomeric composition of alcohols and amines

James A. Dale, +2 more
- 01 Sep 1969 - 
- Vol. 34, Iss: 9, pp 2543-2549
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This article is published in Journal of Organic Chemistry.The article was published on 1969-09-01. It has received 2312 citations till now. The article focuses on the topics: Reagent.

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Journal ArticleDOI

Accurate determination of the extent to which the SE2' reactions of an allenylsilane are stereospecifically anti

Michael J. C. Buckle, +1 more
- 02 Apr 1993 - 
TL;DR: The allenylsilane 1 has been prepared in high enantiomeric purity (98% e.g. as discussed by the authors ) and its SE2′ reaction with adamantyl chloride and isobutyraldehyde are stereospecifically anti to a very high degree (>99:1).
Journal ArticleDOI

Diastereo‐ and Enantioselective Synthesis of Carbocyclic and Heterocyclic β‐Amino Acids by Tandem Aza Michael Addition/Intramolecular Cyclization

Dieter Enders, +1 more
- 01 Apr 1997 - 
TL;DR: In this paper, the stereoselective conjugate addition of (S)-(−)-1-(trimethylsilylamino)-2-(methoxymethyl)pyrrolidine (TMS-SAMP) to ω-halide-substituted α,β-unsaturated esters 1 is utilized to prepare carbocyclic and heterocyCLic β-amino acids 2 and 5 of high diastereo- and enantiomeric purity via the corresponding β-hydrazino esters by selective intramole
Journal ArticleDOI

Determination of the absolute stereochemistry of alcohols and amines by NMR of the group directly linked to the chiral derivatizing reagent

Shamil K. Latypov, +4 more
- 10 Mar 2001 - 
TL;DR: In this article, it was shown that the asymmetry of the substrate (alcohol or amine) leads to the redistribution of the conformer populations of their methoxyphenylacetic acid (MPA) or methoxytrifluoromethylphenylacetamide (MTPA) derivatives rather than to the distortion of conformer geometry as was postulated by Mosher.
Journal ArticleDOI

Chirality sensing by nonchiral porphines

Jan Labuta, +7 more
- 21 Mar 2011 - 
Journal ArticleDOI

Enantioselective Preparation of 2‘,3‘-Dideoxynucleosides and Their Analogues from Ring-Expansion of Cyclobutanones. 2. Synthesis of 2‘,3‘-Dideoxyribosides and (1S,3R)-1- Amino-3-(hydroxymethyl)cyclopentane1

Edward Lee-Ruff, +2 more
- 23 Feb 1996 - 
Related Papers (5)

Nuclear magnetic resonance enantiomer regents. Configurational correlations via nuclear magnetic resonance chemical shifts of diastereomeric mandelate, O-methylmandelate, and .alpha.-methoxy-.alpha.-trifluoromethylphenylacetate (MTPA) esters

James A. Dale, +1 more
- 01 Jan 1973 - 

High-field FT NMR application of Mosher's method. The absolute configurations of marine terpenoids

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