Open AccessJournal Article
Gut bacteria in health and disease.
TLDR
Although this area holds much promise, more high-quality trials of probiotics, prebiotics, and other microbiota-modifying approaches in digestive disorders are needed, as well as laboratory investigations of their mechanisms of action.About:
This article is published in Gastroenterología y Hepatología.The article was published on 2013-09-01 and is currently open access. It has received 319 citations till now. The article focuses on the topics: Gut flora.read more
Citations
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Journal ArticleDOI
Human gut microbiota/microbiome in health and diseases: a review
TL;DR: The role of gut microbiota in maintaining host health is clarified and how nutritional and environmental factors affect the gut microbial structure and function is investigated.
Journal ArticleDOI
Gut microbiome and metabolic syndrome
TL;DR: Modification of gut microbiota via prebiotics, probiotics or other dietary interventions has provided evidence to support a possible beneficial effect of interventions targeting gut microbiota modulation to treat components or complications of metabolic syndrome.
Journal ArticleDOI
Disturbance of the gut microbiota in early-life selectively affects visceral pain in adulthood without impacting cognitive or anxiety-related behaviors in male rats
Siobhain M. O'Mahony,Valeria D. Felice,Kenneth Nally,Hélène M. Savignac,Marcus J. Claesson,Paul Scully,Jerzy A. Woznicki,Niall P. Hyland,Fergus Shanahan,Eamonn Martin Quigley,Julian R. Marchesi,Paul W. O'Toole,T. L. Dinan,John F. Cryan +13 more
TL;DR: A temporary disruption of the gut microbiota in early-life results in very specific and long-lasting changes in visceral sensitivity in male rats, a hallmark of stress-related functional disorders of the brain-gut axis such as irritable bowel disorder.
Journal ArticleDOI
Repeat Treatment With Rifaximin Is Safe and Effective in Patients With Diarrhea-Predominant Irritable Bowel Syndrome
Anthony Lembo,Mark Pimentel,Satish S.C. Rao,Philip Schoenfeld,Brooks D. Cash,Leonard B. Weinstock,Craig Paterson,Enoch Bortey,William P. Forbes +8 more
TL;DR: In a phase 3 study of patients with relapsing symptoms of IBS-D, repeat rifaximin treatment was efficacious and well tolerated and significant improvements were noted for prevention of recurrence, durable response, and bowel movement urgency.
Journal ArticleDOI
Gut microbiota in neurodegenerative disorders.
TL;DR: This review summarizes the current understanding of the role of gut microbiota in neurodegenerative disorders and possible intervention strategies and reveals that intake of probiotics may help in the integrity of intestinal and BBB thus ameliorating the above neurodegenersative disorders.
References
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EDUCATION PRACTICE A 51-Year-Old With Irritable Bowel Syndrome: Test or Treat for Bacterial Overgrowth?
TL;DR: A 51-year-old self-employed male is referred for further valuation of symptoms of abdominal discomfort and bloating uggestive of irritable bowel syndrome (IBS) that have been resent intermittently for the past 20 years.
Journal ArticleDOI
The gut microbiota: a new player in the innate immune stress response?
TL;DR: Evidence is presented that mice exposed to social disruption stress display changes in composition, diversity and number of gut microorganisms, and the first evidence that the gut microbiota may also play a role in innate immunological stress responses or the sterile inflammatory response produced by stressor exposure.
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