Large-Vessel Stroke as a Presenting Feature of Covid-19 in the Young.
Thomas J Oxley,J Mocco,Shahram Majidi,Christopher P. Kellner,Hazem Shoirah,I. Paul Singh,Reade De Leacy,Tomoyoshi Shigematsu,Travis R. Ladner,Kurt A. Yaeger,Maryna Skliut,Jesse Weinberger,Neha S. Dangayach,Joshua B. Bederson,Stanley Tuhrim,Johanna T Fifi +15 more
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TLDR
Five patients younger than 50 years of age with large-vessel stroke and Covid-19 infection presented to a health system in New York City over a 2-week period with signs of stroke and infection.Abstract:
Stroke in Young Patients with Covid-19 Five patients younger than 50 years of age with large-vessel stroke and Covid-19 infection presented to a health system in New York City over a 2-week period....read more
Citations
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Heparin as a Therapy for COVID-19: Current Evidence and Future Possibilities.
Joseph A. Hippensteel,Wells B. LaRivière,James F. Colbert,Christophe Langouet-Astrie,Eric P. Schmidt,Eric P. Schmidt +5 more
TL;DR: P plausibility of heparin for COVID-19 is sufficiently robust to justify urgent randomized controlled trials to determine the safety and effectiveness of this therapy.
Journal ArticleDOI
COVID-19 related neuroimaging findings: A signal of thromboembolic complications and a strong prognostic marker of poor patient outcome.
Rajan Jain,Matthew Young,Siddhant Dogra,Helena Kennedy,Vinh Nguyen,Simon Jones,Seda Bilaloglu,Katherine Hochman,Eytan Raz,Steven L. Galetta,Leora Horwtiz +10 more
TL;DR: A retrospective cohort study of patients admitted to a major healthcare system in New York City between March 1, 2020 and April 13, 2020 demonstrates acute stroke is the most common neuroimaging finding among hospitalized COVID-19 patients.
Journal ArticleDOI
Neurological and Neuropsychiatric Impacts of COVID-19 Pandemic.
TL;DR: A wide index of suspicion is demanded for prompt diagnosis of SARS-CoV-2 to prevent further complications and mortality and most of the psychological effects are secondary to pandemic-associated regulatory, socioeconomic and psychosocial changes.
Journal ArticleDOI
Current Overview on Hypercoagulability in COVID-19.
Namrata Singhania,Saurabh Bansal,Divya P Nimmatoori,A. Ahsan Ejaz,Peter A. McCullough,Girish Singhania +5 more
TL;DR: The current literature available on COVID-19-associated coagulopathy is comprehensively reviewed and the pathogenesis, clinical features, and management of CAC are highlighted.
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Association of hypertension, diabetes, stroke, cancer, kidney disease, and high-cholesterol with COVID-19 disease severity and fatality: A systematic review.
TL;DR: It was observed that diabetes, hypertension, and cholesterol levels possess an apparent relation to COVID-19 severity, and other comorbidities, such as cancer, kidney disease, and stroke must be further evaluated to determine a strong relationship to the virus.
References
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Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study.
Fei Zhou,Ting Yu,Ronghui Du,Guohui Fan,Ying Liu,Zhibo Liu,Jie Xiang,Yeming Wang,Bin Song,Xiaoying Gu,Xiaoying Gu,Lulu Guan,Yuan Wei,Li Hui,Xudong Wu,Jiuyang Xu,Shengjin Tu,Yi Zhang,Hua Chen,Bin Cao +19 more
TL;DR: Wang et al. as discussed by the authors used univariable and multivariable logistic regression methods to explore the risk factors associated with in-hospital death, including older age, high SOFA score and d-dimer greater than 1 μg/mL.
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Large artery ischaemic stroke in severe acute respiratory syndrome (SARS).
T. Umapathi,Ai Ching Kor,Narayanaswamy Venketasubramanian,C. C. Tchoyoson Lim,Boon Chuan Pang,Tseng Tsai Yeo,Cheng Chuan Lee,Poh Lian Lim,Poh Lian Lim,Kuperan Ponnudurai,Khoon Leong Chuah,Puay Hoon Tan,Dessmon Y.H. Tai,Sze Peng Brenda Ang +13 more
TL;DR: It is believed that increased vigilance against stroke and other thrombotic complications among critically-ill SARS patients in future outbreaks is needed, especially if treatment such as intravenous immunoglobulin, that increases pro-thrombosis tendency, is contemplated.
Journal ArticleDOI
Erythropoietin as candidate for supportive treatment of severe COVID-19.
Hannelore Ehrenreich,Karin Weissenborn,Martin Begemann,Martin Begemann,Markus Busch,Eduard Vieta,Kamilla W. Miskowiak +6 more
TL;DR: Evidence that supports the use of human recombinant erythropoietin (EPO) for ameliorating course and outcome of seriously ill COVID-19 patients is recap here and the research design for a double-blind placebo-controlled randomized clinical trial including severely affected patients is planned to start shortly.
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Revisiting the Protein C Pathway: An Opportunity for Adjunctive Intervention in COVID-19?
TL;DR: The objective of this study was to establish a baseline for the evaluation of the Recombinant Human Activated Protein C Worldwide Evaluation in Severe Sepsis.
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COVID-19-associated pulmonary and cerebral thromboembolic disease
TL;DR: A case of a 79-year-old woman that presented with stroke and was found to have COVID-19 pneumonia and concomitant large burden pulmonary arterial clot is reported.
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