Large-Vessel Stroke as a Presenting Feature of Covid-19 in the Young.
Thomas J Oxley,J Mocco,Shahram Majidi,Christopher P. Kellner,Hazem Shoirah,I. Paul Singh,Reade De Leacy,Tomoyoshi Shigematsu,Travis R. Ladner,Kurt A. Yaeger,Maryna Skliut,Jesse Weinberger,Neha S. Dangayach,Joshua B. Bederson,Stanley Tuhrim,Johanna T Fifi +15 more
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TLDR
Five patients younger than 50 years of age with large-vessel stroke and Covid-19 infection presented to a health system in New York City over a 2-week period with signs of stroke and infection.Abstract:
Stroke in Young Patients with Covid-19 Five patients younger than 50 years of age with large-vessel stroke and Covid-19 infection presented to a health system in New York City over a 2-week period....read more
Citations
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Therapeutic potential of mesenchymal stem cells in multiple organs affected by COVID-19.
Gustavo C. Paris,Aline A. Azevedo,Adriana Ferreira,Yanca M.A. Azevedo,Mateus de Almeida Rainho,Genilza Pereira de Oliveira,Karina R Silva,Erika Cortez,Ana Carolina Stumbo,Simone Nunes de Carvalho,Laís de Carvalho,Alessandra Alves Thole +11 more
TL;DR: In this article, mesenchymal stem cells (MSCs) have emerged as potential candidates concerning the promotion of beneficial actions at different stages of COVID-19, which has been causing disorders, dysfunction and morphophysiological alterations in multiple organs as the disease evolves.
Journal ArticleDOI
Angiotensin-converting enzyme 2: from a vasoactive peptide to the gatekeeper of a global pandemic.
TL;DR: In this article, the authors provide a comprehensive overview of angiotensin-converting enzyme 2 (ACE2) as a possible candidate for pharmacological approaches to halt inflammatory processes in different pathogenic conditions.
Journal ArticleDOI
Acute Ischemic Stroke in SARS-CoV, MERS-CoV, SARS-CoV-2: Neurorehabilitation Implications of Inflammation Induced Immunological Responses Affecting Vascular Systems
TL;DR: In this article, a mini-review provides an overview of the commonalities among studies published on all three types of the coronavirus related to acute ischemic stroke (AIS).
Journal ArticleDOI
Neurological Manifestations and Outcomes in a Retrospective Cohort of Mexican Inpatients with SARS-CoV-2 Pneumonia: Design of a Risk Profile
Silvia García,Francisco Manuel Cuatepotzo-Burgos,Christian Gabriel Toledo-Lozano,Adriana Balderrama-Soto,Sofia L. Alcaraz-Estrada,Luis Montiel-López,Alberto Hilarión De la Vega-Bravo,Paul Mondragón-Terán,Maribel Santosbeña-Lagunes,Maricela Escarela-Serrano,Celia Mireya Rodríguez-Martínez,María Del Carmen Méndez-Vidrio,Sandra Muñoz-López,José A Merino-Rajme,Rodrigo Alberto Rodríguez-Briseño,Fidel Cerda-Téllez,Ramón Mauricio Coral-Vázquez,Ramón Mauricio Coral-Vázquez,Sergio Sauri-Suárez,Sandra Quiñonez-Aguilar,Juan Antonio Pineda-Juárez,Juan Antonio Suárez-Cuenca +21 more
TL;DR: In this article, the authors analyzed the neurological manifestations in Mexican patients hospitalized with pneumonia due to COVID-19 and investigated the association between demographic, clinical, and biochemical variables and outcomes, including death.
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Characterization of Hemorrhagic and Ischemic Stroke in a Diverse Cohort of COVID-19 Patients
Alexander D. Ramos,Feliks Koyfman,Kory Byrns,Alan Wu,Jay Yasen,Lauren Elreda,Srikanth R. Boddu,Sammy Pishanidar,Baxter B. Allen,Rupa Juthani +9 more
TL;DR: There is limited data on the influence of demographics, risk factors, and hematologic function on outcomes in COVID-19 strokePatients, and the need for further research is needed to assess the impact of these factors on patient outcomes.
References
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Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study.
Fei Zhou,Ting Yu,Ronghui Du,Guohui Fan,Ying Liu,Zhibo Liu,Jie Xiang,Yeming Wang,Bin Song,Xiaoying Gu,Xiaoying Gu,Lulu Guan,Yuan Wei,Li Hui,Xudong Wu,Jiuyang Xu,Shengjin Tu,Yi Zhang,Hua Chen,Bin Cao +19 more
TL;DR: Wang et al. as discussed by the authors used univariable and multivariable logistic regression methods to explore the risk factors associated with in-hospital death, including older age, high SOFA score and d-dimer greater than 1 μg/mL.
Journal ArticleDOI
Large artery ischaemic stroke in severe acute respiratory syndrome (SARS).
T. Umapathi,Ai Ching Kor,Narayanaswamy Venketasubramanian,C. C. Tchoyoson Lim,Boon Chuan Pang,Tseng Tsai Yeo,Cheng Chuan Lee,Poh Lian Lim,Poh Lian Lim,Kuperan Ponnudurai,Khoon Leong Chuah,Puay Hoon Tan,Dessmon Y.H. Tai,Sze Peng Brenda Ang +13 more
TL;DR: It is believed that increased vigilance against stroke and other thrombotic complications among critically-ill SARS patients in future outbreaks is needed, especially if treatment such as intravenous immunoglobulin, that increases pro-thrombosis tendency, is contemplated.
Journal ArticleDOI
Erythropoietin as candidate for supportive treatment of severe COVID-19.
Hannelore Ehrenreich,Karin Weissenborn,Martin Begemann,Martin Begemann,Markus Busch,Eduard Vieta,Kamilla W. Miskowiak +6 more
TL;DR: Evidence that supports the use of human recombinant erythropoietin (EPO) for ameliorating course and outcome of seriously ill COVID-19 patients is recap here and the research design for a double-blind placebo-controlled randomized clinical trial including severely affected patients is planned to start shortly.
Journal ArticleDOI
Revisiting the Protein C Pathway: An Opportunity for Adjunctive Intervention in COVID-19?
TL;DR: The objective of this study was to establish a baseline for the evaluation of the Recombinant Human Activated Protein C Worldwide Evaluation in Severe Sepsis.
Journal ArticleDOI
COVID-19-associated pulmonary and cerebral thromboembolic disease
TL;DR: A case of a 79-year-old woman that presented with stroke and was found to have COVID-19 pneumonia and concomitant large burden pulmonary arterial clot is reported.
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