Large-Vessel Stroke as a Presenting Feature of Covid-19 in the Young.
Thomas J Oxley,J Mocco,Shahram Majidi,Christopher P. Kellner,Hazem Shoirah,I. Paul Singh,Reade De Leacy,Tomoyoshi Shigematsu,Travis R. Ladner,Kurt A. Yaeger,Maryna Skliut,Jesse Weinberger,Neha S. Dangayach,Joshua B. Bederson,Stanley Tuhrim,Johanna T Fifi +15 more
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TLDR
Five patients younger than 50 years of age with large-vessel stroke and Covid-19 infection presented to a health system in New York City over a 2-week period with signs of stroke and infection.Abstract:
Stroke in Young Patients with Covid-19 Five patients younger than 50 years of age with large-vessel stroke and Covid-19 infection presented to a health system in New York City over a 2-week period....read more
Citations
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SARS-CoV-2 and the Nervous System: From Clinical Features to Molecular Mechanisms.
TL;DR: It is reported that patients with COVID-19 may exhibit a wide range of neurological manifestations, including encephalopathy, encephalitis, seizures, cerebrovascular events, acute polyneuropathy, headache, hypogeusia, and hyposmia, as well as some non-specific symptoms.
Journal ArticleDOI
SARS-CoV-2 and nervous system: From pathogenesis to clinical manifestation.
Kiandokht Keyhanian,Raffaella Pizzolato Umeton,Babak Mohit,Vahid Davoudi,Fatemeh Hajighasemi,Mehdi Ghasemi +5 more
TL;DR: This Review discusses the possible neuroimmunological mechanisms underlying the nervous system and skeletal muscle involvement, and viral triggered neuroIMmunological conditions associated with SARS-CoV-2, as well as therapeutic approaches that have been considered for these specific complications worldwide.
Journal ArticleDOI
Clinical update on COVID-19 for the emergency clinician: Presentation and evaluation
Brit Long,Brandon M Carius,Summer A Chavez,Stephen Y. Liang,William J. Brady,Alex Koyfman,Michael S. Gottlieb +6 more
TL;DR: The first in a two-part series on COVID-19 updates as mentioned in this paper provides a focused overview of the presentation and evaluation of the coronavirus disease of 2019 for emergency clinicians.
Journal ArticleDOI
Stroke and mechanical thrombectomy in patients with COVID-19: technical observations and patient characteristics.
TL;DR: This group of patients with COVID-19 who presented with large vessel occlusion were younger, had tandem or multiple territory occlusions, a large clot burden, and a propensity for clot fragmentation, which present unique challenges that make successful revascularization difficult.
Journal ArticleDOI
Risk factors prediction, clinical outcomes, and mortality in COVID-19 patients.
Roohallah Alizadehsani,Zahra Alizadeh Sani,Mohaddeseh Behjati,Zahra Roshanzamir,Sadiq Hussain,Niloofar Abedini,Fereshteh Hasanzadeh,Abbas Khosravi,Afshin Shoeibi,Afshin Shoeibi,Mohamad Roshanzamir,Pardis Moradnejad,Saeid Nahavandi,Fahime Khozeimeh,Assef Zare,Maryam Panahiazar,U. Rajendra Acharya,U. Rajendra Acharya,U. Rajendra Acharya,Sheikh Mohammed Shariful Islam +19 more
TL;DR: A number of factors associated with mortality due to CO VID‐19 have been investigated for the first time in this study and might be helpful in early prediction and risk reduction of mortality in patients infected with COVID‐19.
References
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Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study.
Fei Zhou,Ting Yu,Ronghui Du,Guohui Fan,Ying Liu,Zhibo Liu,Jie Xiang,Yeming Wang,Bin Song,Xiaoying Gu,Xiaoying Gu,Lulu Guan,Yuan Wei,Li Hui,Xudong Wu,Jiuyang Xu,Shengjin Tu,Yi Zhang,Hua Chen,Bin Cao +19 more
TL;DR: Wang et al. as discussed by the authors used univariable and multivariable logistic regression methods to explore the risk factors associated with in-hospital death, including older age, high SOFA score and d-dimer greater than 1 μg/mL.
Journal ArticleDOI
Large artery ischaemic stroke in severe acute respiratory syndrome (SARS).
T. Umapathi,Ai Ching Kor,Narayanaswamy Venketasubramanian,C. C. Tchoyoson Lim,Boon Chuan Pang,Tseng Tsai Yeo,Cheng Chuan Lee,Poh Lian Lim,Poh Lian Lim,Kuperan Ponnudurai,Khoon Leong Chuah,Puay Hoon Tan,Dessmon Y.H. Tai,Sze Peng Brenda Ang +13 more
TL;DR: It is believed that increased vigilance against stroke and other thrombotic complications among critically-ill SARS patients in future outbreaks is needed, especially if treatment such as intravenous immunoglobulin, that increases pro-thrombosis tendency, is contemplated.
Journal ArticleDOI
Erythropoietin as candidate for supportive treatment of severe COVID-19.
Hannelore Ehrenreich,Karin Weissenborn,Martin Begemann,Martin Begemann,Markus Busch,Eduard Vieta,Kamilla W. Miskowiak +6 more
TL;DR: Evidence that supports the use of human recombinant erythropoietin (EPO) for ameliorating course and outcome of seriously ill COVID-19 patients is recap here and the research design for a double-blind placebo-controlled randomized clinical trial including severely affected patients is planned to start shortly.
Journal ArticleDOI
Revisiting the Protein C Pathway: An Opportunity for Adjunctive Intervention in COVID-19?
TL;DR: The objective of this study was to establish a baseline for the evaluation of the Recombinant Human Activated Protein C Worldwide Evaluation in Severe Sepsis.
Journal ArticleDOI
COVID-19-associated pulmonary and cerebral thromboembolic disease
TL;DR: A case of a 79-year-old woman that presented with stroke and was found to have COVID-19 pneumonia and concomitant large burden pulmonary arterial clot is reported.
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