Large-Vessel Stroke as a Presenting Feature of Covid-19 in the Young.
Thomas J Oxley,J Mocco,Shahram Majidi,Christopher P. Kellner,Hazem Shoirah,I. Paul Singh,Reade De Leacy,Tomoyoshi Shigematsu,Travis R. Ladner,Kurt A. Yaeger,Maryna Skliut,Jesse Weinberger,Neha S. Dangayach,Joshua B. Bederson,Stanley Tuhrim,Johanna T Fifi +15 more
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TLDR
Five patients younger than 50 years of age with large-vessel stroke and Covid-19 infection presented to a health system in New York City over a 2-week period with signs of stroke and infection.Abstract:
Stroke in Young Patients with Covid-19 Five patients younger than 50 years of age with large-vessel stroke and Covid-19 infection presented to a health system in New York City over a 2-week period....read more
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Neurological Disorders associated with COVID-19 Hospital Admissions : Experience of a Single Tertiary Healthcare Centre
Permesh Singh Dhillon,Robert A. Dineen,Haley Morris,Radu Tanasescu,Esmaeil Nikfekr,Jonathan Evans,Cris S. Constantinescu,Akram A. Hosseini +7 more
TL;DR: Although the exact prevalence and aetiology remains unclear, non- sporadic new onset of neurological disorders, in addition to anosmia, occurs during the acute COVID-19-infection.
Posted ContentDOI
Investigation of the relationship between inherited thrombophilia and novel coronavirus pneumonia
TL;DR: This study is the first to rule out the relationship of rs1799963 (FII), rs6025 (FV) andrs1799768 (PAI-1) with severe NCP, a disease caused by severe acute respiratory syndrome coronavirus 2 virus.
Journal ArticleDOI
A case of malignant cerebral infarction associated with COVID-19 infection.
TL;DR: A case of a 46-year-old healthcare worker with COVID-19 who developed malignant cerebral infarction requiring emergency decompressive craniectomy is described, illustrating the neurosurgical implications associated with inflammatory and pro-coagulopathic derangements in CO VID-19 disease.
Journal ArticleDOI
Delirium and Cognitive Impairment as Predisposing Factors of COVID-19 Infection in Neuropsychiatric Patients: A Narrative Review.
Michele Fabrazzo,Antonio Russo,Alessio Camerlengo,Claudia Tucci,Mario Luciano,Valeria De Santis,Francesco Perris,Francesco Catapano,Nicola Coppola +8 more
TL;DR: In this article, the authors discuss the mechanisms underlying the neuroinvasive/neurotropic properties of SARS-CoV-2 and the subsequent mental complications, which may underlie delirium onset and neuropsychiatric outcomes.
Journal ArticleDOI
Serum neurofilament light chain levels in Covid-19 patients without major neurological manifestations
Federico Verde,Ilaria Milone,I. Bulgarelli,Silvia Peverelli,Claudia Colombrita,Alessio Maranzano,Narghes Calcagno,Nicola Ticozzi,Giovanni Battista Perego,Gianfranco Parati,Erminio Torresani,Antonia Ratti,Vincenzo Silani +12 more
TL;DR: In this paper , the authors investigated whether sNFL is increased in Covid-19 patients without major neurological manifestations, is associated with disease severity, respiratory and routine blood parameters, and changes longitudinally in the short term.
References
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Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study.
Fei Zhou,Ting Yu,Ronghui Du,Guohui Fan,Ying Liu,Zhibo Liu,Jie Xiang,Yeming Wang,Bin Song,Xiaoying Gu,Xiaoying Gu,Lulu Guan,Yuan Wei,Li Hui,Xudong Wu,Jiuyang Xu,Shengjin Tu,Yi Zhang,Hua Chen,Bin Cao +19 more
TL;DR: Wang et al. as discussed by the authors used univariable and multivariable logistic regression methods to explore the risk factors associated with in-hospital death, including older age, high SOFA score and d-dimer greater than 1 μg/mL.
Journal ArticleDOI
Large artery ischaemic stroke in severe acute respiratory syndrome (SARS).
T. Umapathi,Ai Ching Kor,Narayanaswamy Venketasubramanian,C. C. Tchoyoson Lim,Boon Chuan Pang,Tseng Tsai Yeo,Cheng Chuan Lee,Poh Lian Lim,Poh Lian Lim,Kuperan Ponnudurai,Khoon Leong Chuah,Puay Hoon Tan,Dessmon Y.H. Tai,Sze Peng Brenda Ang +13 more
TL;DR: It is believed that increased vigilance against stroke and other thrombotic complications among critically-ill SARS patients in future outbreaks is needed, especially if treatment such as intravenous immunoglobulin, that increases pro-thrombosis tendency, is contemplated.
Journal ArticleDOI
Erythropoietin as candidate for supportive treatment of severe COVID-19.
Hannelore Ehrenreich,Karin Weissenborn,Martin Begemann,Martin Begemann,Markus Busch,Eduard Vieta,Kamilla W. Miskowiak +6 more
TL;DR: Evidence that supports the use of human recombinant erythropoietin (EPO) for ameliorating course and outcome of seriously ill COVID-19 patients is recap here and the research design for a double-blind placebo-controlled randomized clinical trial including severely affected patients is planned to start shortly.
Journal ArticleDOI
Revisiting the Protein C Pathway: An Opportunity for Adjunctive Intervention in COVID-19?
TL;DR: The objective of this study was to establish a baseline for the evaluation of the Recombinant Human Activated Protein C Worldwide Evaluation in Severe Sepsis.
Journal ArticleDOI
COVID-19-associated pulmonary and cerebral thromboembolic disease
TL;DR: A case of a 79-year-old woman that presented with stroke and was found to have COVID-19 pneumonia and concomitant large burden pulmonary arterial clot is reported.
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