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Open AccessJournal ArticleDOI

Large-Vessel Stroke as a Presenting Feature of Covid-19 in the Young.

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TLDR
Five patients younger than 50 years of age with large-vessel stroke and Covid-19 infection presented to a health system in New York City over a 2-week period with signs of stroke and infection.
Abstract
Stroke in Young Patients with Covid-19 Five patients younger than 50 years of age with large-vessel stroke and Covid-19 infection presented to a health system in New York City over a 2-week period....

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Citations
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Coronaviruses and Central Nervous System Manifestations

TL;DR: This minireview scans the literature regarding the involvement of the CNS in coronavirus infections in general, and in regard to the recent SARS-CoV-2, specifically.
Journal ArticleDOI

A Review of Pathophysiology, Clinical Features, and Management Options of COVID-19 Associated Coagulopathy.

TL;DR: In this article, the authors discuss the current literature on laboratory coagulation disruptions associated with COVID-19 and the clinical effects of thromboembolic events including pulmonary embolism (PE), deep vein thrombosis (DVT), peripheral arterial thrommosis, and acute ischemic stroke.
Journal ArticleDOI

COVID-19: A Review for the Pediatric Neurologist.

TL;DR: This review consolidates current data on the disease associated with SARS-CoV-2, called COVID-19, and information from past coronavirus epidemics, to discuss diseases of pediatric neurology including Guillain-Barre syndrome.
Journal ArticleDOI

How we should respond to the Coronavirus SARS-CoV-2 outbreak: A German perspective.

TL;DR: By normalizing daily case numbers, the plateau day of the current outbreak in Germany could be calculated to be reached at April 12, 2020 (day 103 of 2020), the time point at which no further new infections will occur if the epidemic situation remains stable.
References
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Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study.

TL;DR: Wang et al. as discussed by the authors used univariable and multivariable logistic regression methods to explore the risk factors associated with in-hospital death, including older age, high SOFA score and d-dimer greater than 1 μg/mL.
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Large artery ischaemic stroke in severe acute respiratory syndrome (SARS).

TL;DR: It is believed that increased vigilance against stroke and other thrombotic complications among critically-ill SARS patients in future outbreaks is needed, especially if treatment such as intravenous immunoglobulin, that increases pro-thrombosis tendency, is contemplated.
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Erythropoietin as candidate for supportive treatment of severe COVID-19.

TL;DR: Evidence that supports the use of human recombinant erythropoietin (EPO) for ameliorating course and outcome of seriously ill COVID-19 patients is recap here and the research design for a double-blind placebo-controlled randomized clinical trial including severely affected patients is planned to start shortly.
Journal ArticleDOI

Revisiting the Protein C Pathway: An Opportunity for Adjunctive Intervention in COVID-19?

TL;DR: The objective of this study was to establish a baseline for the evaluation of the Recombinant Human Activated Protein C Worldwide Evaluation in Severe Sepsis.
Journal ArticleDOI

COVID-19-associated pulmonary and cerebral thromboembolic disease

TL;DR: A case of a 79-year-old woman that presented with stroke and was found to have COVID-19 pneumonia and concomitant large burden pulmonary arterial clot is reported.
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