Large-Vessel Stroke as a Presenting Feature of Covid-19 in the Young.
Thomas J Oxley,J Mocco,Shahram Majidi,Christopher P. Kellner,Hazem Shoirah,I. Paul Singh,Reade De Leacy,Tomoyoshi Shigematsu,Travis R. Ladner,Kurt A. Yaeger,Maryna Skliut,Jesse Weinberger,Neha S. Dangayach,Joshua B. Bederson,Stanley Tuhrim,Johanna T Fifi +15 more
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TLDR
Five patients younger than 50 years of age with large-vessel stroke and Covid-19 infection presented to a health system in New York City over a 2-week period with signs of stroke and infection.Abstract:
Stroke in Young Patients with Covid-19 Five patients younger than 50 years of age with large-vessel stroke and Covid-19 infection presented to a health system in New York City over a 2-week period....read more
Citations
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COVID-19 and stroke: Experience in a Ghanaian healthcare system.
Fred Stephen Sarfo,Fred Stephen Sarfo,Naa Oboshie Mensah,Francis Agyapong Opoku,Nathaniel Adusei-Mensah,Michael Ampofo,Bruce Ovbiagele +6 more
TL;DR: The COVID-19 outbreak coincided with a comparatively significant rise in initial and recurrent stroke admissions at this Ghanaian tertiary hospital, and the influence of secular trends cannot be excluded.
Journal ArticleDOI
Coagulopathies after Vaccination against SARS-CoV-2 May Be Derived from a Combined Effect of SARS-CoV-2 Spike Protein and Adenovirus Vector-Triggered Signaling Pathways.
TL;DR: In this paper, a review summarizes current data and hypotheses for molecular and cellular mechanisms into one integrated hypothesis indicating that coagulopathies, including thromboses, throm bocytopenia, and other related side effects, are correlated to an interplay of the two components in the vaccine, i.e., the spike antigen and the adenoviral vector, with the innate and immune systems.
Journal ArticleDOI
The professional and personal impact of the coronavirus pandemic on US neurointerventional practices: a nationwide survey.
Kyle M Fargen,Thabele M Leslie-Mazwi,Richard P. Klucznik,Stacey Q Wolfe,Patrick A. Brown,Sameer A. Ansari,Guilherme Dabus,Alejandro M Spiotta,Maxim Mokin,Ameer E Hassan,David S Liebeskind,Babu G. Welch,Adnan H. Siddiqui,Joshua A Hirsch +13 more
TL;DR: This is the first study designed to understand the effects of the COVID-19 pandemic on NI physician practices, case volumes, compensation, personal/family stresses, and work-related burnout, and future studies examining these factors following the resumption of elective cases and relaxing of social distancing measures will be necessary.
Journal ArticleDOI
Covid-19 and coagulopathy.
TL;DR: In this paper, the authors reviewed the epidemiology, clinical features, mechanisms, and treatment of COVID-19-associated coagulopathy and found that the COVID19 infection has been associated with a heightened risk of thromboembolic complications such as inflammation, endotheliitis, hyperviscosity, and hypercoagulability.
Journal ArticleDOI
Inpatient Neurology Consultations During the Onset of the SARS-CoV-2 New York City Pandemic: A Single Center Case Series
Sara Radmard,Samantha Epstein,Hannah J. Roeder,Andrew J. Michalak,Steven D. Shapiro,Amelia K. Boehme,Tommy J. Wilson,Juan Carlos Duran,Jennifer M. Bain,Joshua Z. Willey,Kiran T. Thakur +10 more
TL;DR: This small case series of initial encounters with COVID-19 infection describes a range of neurological complications which are similar to presentations seen with other critical illnesses.
References
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Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study.
Fei Zhou,Ting Yu,Ronghui Du,Guohui Fan,Ying Liu,Zhibo Liu,Jie Xiang,Yeming Wang,Bin Song,Xiaoying Gu,Xiaoying Gu,Lulu Guan,Yuan Wei,Li Hui,Xudong Wu,Jiuyang Xu,Shengjin Tu,Yi Zhang,Hua Chen,Bin Cao +19 more
TL;DR: Wang et al. as discussed by the authors used univariable and multivariable logistic regression methods to explore the risk factors associated with in-hospital death, including older age, high SOFA score and d-dimer greater than 1 μg/mL.
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Large artery ischaemic stroke in severe acute respiratory syndrome (SARS).
T. Umapathi,Ai Ching Kor,Narayanaswamy Venketasubramanian,C. C. Tchoyoson Lim,Boon Chuan Pang,Tseng Tsai Yeo,Cheng Chuan Lee,Poh Lian Lim,Poh Lian Lim,Kuperan Ponnudurai,Khoon Leong Chuah,Puay Hoon Tan,Dessmon Y.H. Tai,Sze Peng Brenda Ang +13 more
TL;DR: It is believed that increased vigilance against stroke and other thrombotic complications among critically-ill SARS patients in future outbreaks is needed, especially if treatment such as intravenous immunoglobulin, that increases pro-thrombosis tendency, is contemplated.
Journal ArticleDOI
Erythropoietin as candidate for supportive treatment of severe COVID-19.
Hannelore Ehrenreich,Karin Weissenborn,Martin Begemann,Martin Begemann,Markus Busch,Eduard Vieta,Kamilla W. Miskowiak +6 more
TL;DR: Evidence that supports the use of human recombinant erythropoietin (EPO) for ameliorating course and outcome of seriously ill COVID-19 patients is recap here and the research design for a double-blind placebo-controlled randomized clinical trial including severely affected patients is planned to start shortly.
Journal ArticleDOI
Revisiting the Protein C Pathway: An Opportunity for Adjunctive Intervention in COVID-19?
TL;DR: The objective of this study was to establish a baseline for the evaluation of the Recombinant Human Activated Protein C Worldwide Evaluation in Severe Sepsis.
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COVID-19-associated pulmonary and cerebral thromboembolic disease
TL;DR: A case of a 79-year-old woman that presented with stroke and was found to have COVID-19 pneumonia and concomitant large burden pulmonary arterial clot is reported.
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